Eradication of T-ALL cells by CD7-targeted universal CAR-T cells and initial test of ruxolitinib-based CRS management S Li, X Wang, Z Yuan, L Liu, L Luo, Y Li, K Wu, J Liu, C Yang, Z Li, ... Clinical Cancer Research 27 (5), 1242-1246, 2021 | 98 | 2021 |
Development of a chimeric antigen receptor targeting C-type lectin-like molecule-1 for human acute myeloid leukemia E Laborda, M Mazagova, S Shao, X Wang, H Quirino, AK Woods, ... International journal of molecular sciences 18 (11), 2259, 2017 | 82 | 2017 |
IL-17A–induced PLET1 expression contributes to tissue repair and colon tumorigenesis JA Zepp, J Zhao, C Liu, K Bulek, L Wu, X Chen, Y Hao, Z Wang, X Wang, ... The Journal of Immunology 199 (11), 3849-3857, 2017 | 69 | 2017 |
Identification of FABP5 as an immunometabolic marker in human hepatocellular carcinoma F Liu, W Liu, S Zhou, C Yang, M Tian, G Jia, H Wang, B Zhu, M Feng, Y Lu, ... Journal for immunotherapy of cancer 8 (2), e000501, 2020 | 49 | 2020 |
Lipid and protein co-regulation of PI3K effectors Akt and Itk in lymphocytes X Wang, LB Hills, YH Huang Frontiers in immunology 6, 117, 2015 | 45 | 2015 |
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells BB Madison, D Patil, M Richter, X Li, M Tong, S Cranert, X Wang, R Martin, ... Molecular Therapy-Nucleic Acids 29, 979-995, 2022 | 36 | 2022 |
Mst1 kinase regulates the actin-bundling protein L-plastin to promote T cell migration X Xu, X Wang, EM Todd, ER Jaeger, JL Vella, OL Mooren, Y Feng, J Hu, ... The Journal of Immunology 197 (5), 1683-1691, 2016 | 36 | 2016 |
Abstract CT052: Clinical safety and efficacy study of TruUCAR™ GC027: The first-in-human, universal CAR-T therapy for adult relapsed/refractory T-cell acute lymphoblastic … X Wang, S Li, L Gao, Z Yuan, K Wu, L Liu, L Luo, Y Liu, C Zhang, J Liu, ... Cancer Research 80 (16_Supplement), CT052-CT052, 2020 | 31 | 2020 |
A novel BCMA-specific, centyrin-based CAR-T product for the treatment of multiple myeloma DL Hermanson, BE Barnett, S Rengarajan, R Codde, X Wang, Y Tan, ... Blood 128 (22), 2127, 2016 | 30 | 2016 |
Exploiting T cell signaling to optimize engineered T cell therapies H Wang, X Song, L Shen, X Wang, C Xu Trends in Cancer 8 (2), 123-134, 2022 | 24 | 2022 |
piggyBacTM-produced CAR-T cells exhibit stem-cell memory phenotype BE Barnett, DL Hermanson, JB Smith, X Wang, Y Tan, CE Martin, ... Blood 128 (22), 2167, 2016 | 24 | 2016 |
Calmodulin and PI(3,4,5)P3 cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production X Wang, SE Boyken, J Hu, X Xu, RP Rimer, MA Shea, AS Shaw, ... Science signaling 7 (337), ra74-ra74, 2014 | 24 | 2014 |
Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration X Xu, ER Jaeger, X Wang, E Lagler-Ferrez, S Batalov, NL Mathis, ... PloS one 9 (8), e105561, 2014 | 22 | 2014 |
Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor OY Lubman, M Cella, X Wang, K Monte, DJ Lenschow, YH Huang, ... Journal of virology 88 (1), 538-546, 2014 | 21 | 2014 |
CD7 targeted “off-the-shelf” CAR-T demonstrates robust in vivo expansion and high efficacy in the treatment of patients with relapsed and refractory T cell malignancies S Li, X Wang, L Liu, J Liu, J Rao, Z Yuan, L Gao, Y Li, L Luo, G Li, Z Li, ... Leukemia 37 (11), 2176-2186, 2023 | 14 | 2023 |
Safety and efficacy results of GC027: The first-in-human, universal CAR-T cell therapy for adult relapsed/refractory T-cell acute lymphoblastic leukemia (r/r T-ALL). X Wang, S Li, L Gao, Z Yuan, K Wu, L Liu, L Luo, Y Liu, C Zhang, J Liu, ... Journal of Clinical Oncology 38 (15_suppl), 3013-3013, 2020 | 13 | 2020 |
An accurate quantitative method for screening effective siRNA probes targeting a Hepatitis B virus transcript in single living cells W Tong, Y Zhou, X Wang, F Yang, KL Wu, J Wu, Y Zhang Biochemical and biophysical research communications 367 (4), 866-873, 2008 | 10 | 2008 |
B-Cell Maturation Antigen (BCMA)-Specific, CentyrinTM-Based, PiggyBacTM-Transposed CAR-T Memory Stem Cells Are Effective Against p53-/- and Patient … R Mathur, BE Barnett, D Hermanson, J He, Z Zhang, S Rengarajan, ... Blood, The Journal of the American Society of Hematology 130 (Suppl_1), 3068 …, 2017 | 9 | 2017 |
Abstract LB147: Updates on clinical safety and efficacy result of GC027, the first-in-human,“Off-the-Shelf” CD7 CAR-T stand-alone therapy for adult patients with relapsed … S Li, L Gao, Z Yuan, K Wu, L Liu, L Luo, Y Liu, C Zhang, Y Li, D Wang, Z Li, ... Cancer Research 81 (13_Supplement), LB147-LB147, 2021 | 7 | 2021 |
Production of universal anti-Bcma CAR-T cells with reduced alloreactivity, but potent effector function for the treatment of multiple myeloma X Wang, BE Barnett, C Martin, D Hermanson, X Li, J Smith, J Wu, ... Blood 130, 503, 2017 | 5 | 2017 |