| Cancer stem cells—perspectives on current status and future directions: AACR Workshop on cancer stem cells MF Clarke, JE Dick, PB Dirks, CJ Eaves, CHM Jamieson, DL Jones, ... Cancer research 66 (19), 9339-9344, 2006 | 4093 | 2006 |
| The clonal and mutational evolution spectrum of primary triple-negative breast cancers SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ... Nature 486 (7403), 395-399, 2012 | 2362 | 2012 |
| Purification and unique properties of mammary epithelial stem cells J Stingl, P Eirew, I Ricketson, M Shackleton, F Vaillant, D Choi, HI Li, ... Nature 439 (7079), 993-997, 2006 | 1947 | 2006 |
| Cancer stem cells: an evolving concept LV Nguyen, R Vanner, P Dirks, CJ Eaves Nature Reviews Cancer 12 (2), 133-143, 2012 | 1419 | 2012 |
| Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells RD Morin, MD O’Connor, M Griffith, F Kuchenbauer, A Delaney, ... Genome research 18 (4), 610-621, 2008 | 1382 | 2008 |
| Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro HJ Sutherland, CJ Eaves, AC Eaves, W Dragowska, PM Lansdorp | 929 | 1989 |
| Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. HJ Sutherland, PM Lansdorp, DH Henkelman, AC Eaves, CJ Eaves Proceedings of the National Academy of Sciences 87 (9), 3584-3588, 1990 | 903 | 1990 |
| Cancer stem cell definitions and terminology: the devil is in the details P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ... Nature Reviews Cancer 12 (11), 767-775, 2012 | 849 | 2012 |
| Long-term propagation of distinct hematopoietic differentiation programs in vivo B Dykstra, D Kent, M Bowie, L McCaffrey, M Hamilton, K Lyons, SJ Lee, ... Cell stem cell 1 (2), 218-229, 2007 | 774 | 2007 |
| Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. G Sauvageau, U Thorsteinsdottir, CJ Eaves, HJ Lawrence, C Largman, ... Genes & development 9 (14), 1753-1765, 1995 | 774 | 1995 |
| Correction of sickle cell disease in transgenic mouse models by gene therapy R Pawliuk, KA Westerman, ME Fabry, E Payen, R Tighe, EE Bouhassira, ... Science 294 (5550), 2368-2371, 2001 | 747 | 2001 |
| Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia M Škrtić, S Sriskanthadevan, B Jhas, M Gebbia, X Wang, Z Wang, ... Cancer cell 20 (5), 674-688, 2011 | 720 | 2011 |
| Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines. JS Greenberger, MA Sakakeeny, RK Humphries, CJ Eaves, RJ Eckner Proceedings of the National Academy of Sciences 80 (10), 2931-2935, 1983 | 690 | 1983 |
| Hematopoietic stem cells: concepts, definitions, and the new reality CJ Eaves Blood, The Journal of the American Society of Hematology 125 (17), 2605-2613, 2015 | 688 | 2015 |
| Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. G Sauvageau, PM Lansdorp, CJ Eaves, DE Hogge, WH Dragowska, ... Proceedings of the National Academy of Sciences 91 (25), 12223-12227, 1994 | 685 | 1994 |
| Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ... Nature 518 (7539), 422-426, 2015 | 679 | 2015 |
| Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia T Holyoake, X Jiang, C Eaves, A Eaves Blood, The Journal of the American Society of Hematology 94 (6), 2056-2064, 1999 | 673 | 1999 |
| Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal I Fares, J Chagraoui, Y Gareau, S Gingras, R Ruel, N Mayotte, E Csaszar, ... Science 345 (6203), 1509-1512, 2014 | 660 | 2014 |
| Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin KG Leong, K Niessen, I Kulic, A Raouf, C Eaves, I Pollet, A Karsan The Journal of experimental medicine 204 (12), 2935-2948, 2007 | 612 | 2007 |
| Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy. SJ Szilvassy, RK Humphries, PM Lansdorp, AC Eaves, CJ Eaves Proceedings of the National Academy of Sciences 87 (22), 8736-8740, 1990 | 611 | 1990 |
