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MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
SQ Zheng, E Palovcak, JP Armache, KA Verba, Y Cheng, DA Agard
Nature methods 14 (4), 331-332, 2017
68612017
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
47512020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6942020
Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase
KA Verba, RYR Wang, A Arakawa, Y Liu, M Shirouzu, S Yokoyama, ...
Science 352 (6293), 1542-1547, 2016
4372016
How Hsp90 and Cdc37 lubricate kinase molecular switches
KA Verba, DA Agard
Trends in biochemical sciences 42 (10), 799-811, 2017
1032017
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes
M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ...
Research square, rs. 3. rs-515215, 2021
882021
Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface
D Diwanji, R Trenker, TM Thaker, F Wang, DA Agard, KA Verba, N Jura
Nature 600 (7888), 339-343, 2021
842021
Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity
TO Street, LA Lavery, KA Verba, CT Lee, MP Mayer, DA Agard
Journal of molecular biology 415 (1), 3-15, 2012
662012
SARS-CoV-2 variants evolve convergent strategies to remodel the host response
M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ...
Cell 186 (21), 4597-4614. e26, 2023
612023
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583, 459-468, 2020
612020
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM
M Sun, CM Azumaya, E Tse, DP Bulkley, MB Harrington, G Gilbert, A Frost, ...
Journal of structural biology 213 (3), 107745, 2021
572021
Drugging the “undruggable” MYCN oncogenic transcription factor: overcoming previous obstacles to impact childhood cancers
AJ Wolpaw, R Bayliss, G Büchel, CV Dang, M Eilers, WC Gustafson, ...
Cancer research 81 (7), 1627-1632, 2021
502021
Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories
M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne, MR Ummadi, C Ye, ...
bioRxiv, 2022.10. 19.512927, 2022
142022
Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4
X Zhou, S Kong, A Maker, SG Remesh, KK Leung, KA Verba, JA Wells
Nature Chemical Biology 20 (6), 742-750, 2024
122024
Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3
CE Peters, U Schulze-Gahmen, M Eckhardt, GM Jang, J Xu, EH Pulido, ...
Nature Communications 13 (1), 5282, 2022
112022
Atomic structure of Hsp90: Cdc37: Cdk4 reveals Hsp90 regulates kinase via dramatic unfolding
KA Verba, RYR Wang, A Arakawa, Y Liu, M Shirouzu, S Yokoyama, ...
Science (New York, NY) 352 (6293), 1542, 2016
72016
Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
R Trenker, D Diwanji, T Bingham, KA Verba, N Jura
Elife 12, RP92873, 2024
52024
Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3
H Torosyan, MD Paul, A Forget, M Lo, D Diwanji, K Pawłowski, NJ Krogan, ...
Nature communications 14 (1), 3543, 2023
52023
Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps
SG Remesh, GE Merz, AF Brilot, US Chio, AN Rizo, TH Pospiech, I Lui, ...
Structure 31 (3), 253-264. e6, 2023
42023
Structures of the active HER2/HER3 receptor complex reveal dynamics at the dimerization interface induced by binding of a single ligand
D Diwanji, R Trenker, TM Thaker, F Wang, DA Agard, KA Verba, N Jura
bioRxiv, 2021.05. 03.442258, 2021
42021
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Artikelen 1–20