Transition of mesenchymal and epithelial cancer cells depends on α1-4 galactosyltransferase-mediated glycosphingolipids F Jacob, S Alam, M Konantz, CY Liang, RS Kohler, AV Everest-Dass, ... Cancer research 78 (11), 2952-2965, 2018 | 57 | 2018 |
The glycosphingolipid P1 is an ovarian cancer-associated carbohydrate antigen involved in migration F Jacob, M Anugraham, T Pochechueva, BWC Tse, S Alam, R Guertler, ... British journal of cancer 111 (8), 1634-1645, 2014 | 54 | 2014 |
Glucosylceramide synthase inhibitors differentially affect expression of glycosphingolipids S Alam, A Fedier, RS Kohler, F Jacob Glycobiology 25 (4), 351-356, 2015 | 36 | 2015 |
Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways C Cumin, YL Huang, C Rossdam, F Ruoff, SP Cespedes, CY Liang, ... Cell Reports 40 (7), 2022 | 34 | 2022 |
Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells S Alam, M Anugraham, YL Huang, RS Kohler, T Hettich, K Winkelbach, ... Scientific reports 7 (1), 45367, 2017 | 34 | 2017 |
Naturally occurring anti-glycan antibodies binding to Globo H-expressing cells identify ovarian cancer patients T Pochechueva, S Alam, A Schötzau, A Chinarev, NV Bovin, NF Hacker, ... Journal of ovarian research 10, 1-6, 2017 | 27 | 2017 |
Exploring the signaling space of a GPCR using bivalent ligands with a rigid oligoproline backbone N Romantini, S Alam, S Dobitz, M Spillmann, M De Foresta, R Schibli, ... Proceedings of the National Academy of Sciences 118 (48), e2108776118, 2021 | 11 | 2021 |
Evaluation of bivalent peptides as radioligands for peptide receptor radionuclide therapy of prostate cancer N Romantini, S Dobitz, S Alam, M Spillmann, R Schibli, X Deupi, ... JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 62, S559-S559, 2019 | | 2019 |
A4GALT-related glycosphingolipids play a pivotal role in the reversible transition of mesenchymal and epithelial ovarian cancer cells and hence are important regulators of … F Jacob, S Alam, CY Liang, R Kohler, M Nonantz, A Everest-Dass, ... Geburtshilfe und Frauenheilkunde 78 (10), P 152, 2018 | | 2018 |
Glycosphingolipids trigger reversible transition of mesenchymal and epithelial ovarian cancer cells F Jacob, S Alam, CY Liang, M Konantz, YL Huang, A Fedier, N Rimmer, ... CLINICAL & EXPERIMENTAL METASTASIS 34 (8), 504-504, 2017 | | 2017 |
Neolacto glycosphingolipids promote Doxorubicin, Epirubicin, and organoarsenic PENAO sensitivity and hypoxia-induced HIF-1a accumulation in ovarian cancer cells A Fedier, S Alam, K Winkelbach, R Kohler, V Heinzelmann-Schwarz, ... Geburtshilfe und Frauenheilkunde 76 (10), P070, 2016 | | 2016 |
Genetic disruption of the A4GALT (α-1-4-galactosyltransferase) gene depletes globosides and P1 in IGROV1 ovarian cancer cells. S Alam, R Kohler, S, M Lopez, N, A Fedier, V Heinzelmann, F Jacob Glycoconjugate Journal 32, 173-342, 2015 | | 2015 |
Abstract POSTER-BIOL-1322: Natural anti-glycan IgM recognize P1 glycosphingolipid expressed on ovarian cancer cells F Jacob, M Anugraham, T Pochechueva, BWC Tse, S Alam, R Guertler, ... Clinical Cancer Research 21 (16_Supplement), POSTER-BIOL-1322-POSTER-BIOL-1322, 2015 | | 2015 |
P1 glycosphingolipid is an ovarian cancer-associated carbohydrate antigen and enhances cell migration F Jacob, M Anugraham, T Pochechueva, BWC Tse, S Alam, R Guertler, ... International Journal of Gynecological Cancer 24 (S2 8), 240-241, 2014 | | 2014 |
Abstract B23: P1 glycosphingolipid is expressed on ovarian cancer cells recognized by naturally occurring anti-P1 antibodies F Jacob, M Anugraham, A Shahidul, N Bovin, N Packer, N Hacker, ... Clinical Cancer Research 19 (19_Supplement), B23-B23, 2013 | | 2013 |