| IL-11 is a crucial determinant of cardiovascular fibrosis S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ... Nature 552 (7683), 110-115, 2017 | 588 | 2017 |
| Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ... Science translational medicine 11 (511), eaaw1237, 2019 | 251 | 2019 |
| Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ... Gastroenterology 157 (3), 777-792. e14, 2019 | 251 | 2019 |
| Characterising the loss-of-function impact of 5’untranslated region variants in 15,708 individuals N Whiffin, KJ Karczewski, X Zhang, S Chothani, MJ Smith, DG Evans, ... Nature communications 11 (1), 2523, 2020 | 154 | 2020 |
| deltaTE: Detection of translationally regulated genes by integrative analysis of Ribo‐seq and RNA‐seq data S Chothani, E Adami, JF Ouyang, S Viswanathan, N Hubner, SA Cook, ... Current protocols in molecular biology 129 (1), e108, 2019 | 118 | 2019 |
| Widespread translational control of fibrosis in the human heart by RNA-binding proteins S Chothani, S Schäfer, E Adami, S Viswanathan, AA Widjaja, SR Langley, ... Circulation 140 (11), 937-951, 2019 | 118 | 2019 |
| Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ... Nature Communications 12 (1), 66, 2021 | 106 | 2021 |
| Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity CQE Lee, B Kerouanton, S Chothani, S Zhang, Y Chen, CK Mantri, ... Nature communications 12 (1), 2130, 2021 | 87 | 2021 |
| A high-resolution map of human RNA translation SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ... Molecular cell 82 (15), 2885-2899. e8, 2022 | 78 | 2022 |
| Fibroblast‐specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease B Ng, J Dong, S Viswanathan, AA Widjaja, BS Paleja, E Adami, NSJ Ko, ... The FASEB Journal 34 (9), 11802-11815, 2020 | 58 | 2020 |
| Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ... Science translational medicine 13 (597), eaba8146, 2021 | 56 | 2021 |
| Inhibition of IL-11 signalling extends mammalian healthspan and lifespan AA Widjaja, WW Lim, S Viswanathan, S Chothani, B Corden, CM Dasan, ... Nature 632 (8023), 157-165, 2024 | 53 | 2024 |
| Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy AA Widjaja, SP Chothani, SA Cook Human vaccines & immunotherapeutics 16 (10), 2357-2362, 2020 | 51 | 2020 |
| IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts E Adami, S Viswanathan, AA Widjaja, B Ng, S Chothani, N Zhihao, J Tan, ... Rheumatology 60 (12), 5820-5826, 2021 | 50 | 2021 |
| IL11 stimulates IL33 expression and proinflammatory fibroblast activation across tissues AA Widjaja, S Chothani, S Viswanathan, JWT Goh, WW Lim, SA Cook International Journal of Molecular Sciences 23 (16), 8900, 2022 | 48 | 2022 |
| Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis B Ng, AA Widjaja, S Viswanathan, J Dong, SP Chothani, S Lim, ... Scientific Reports 11 (1), 14088, 2021 | 40 | 2021 |
| Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease AA Widjaja, S Viswanathan, SG Shekeran, E Adami, WW Lim, S Chothani, ... Nature Communications 13 (1), 7497, 2022 | 38 | 2022 |
| LASER server: ancestry tracing with genotypes or sequence reads D Taliun, SP Chothani, S Schönherr, L Forer, M Boehnke, GR Abecasis, ... Bioinformatics 33 (13), 2056-2058, 2017 | 37 | 2017 |
| Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo J Zhou, B Ng, NSJ Ko, LR Fiedler, E Khin, A Lim, NE Sahib, Y Wu, ... Human molecular genetics 28 (12), 1971-1981, 2019 | 32 | 2019 |
| Whole-genome sequencing of Finnish type 1 diabetic siblings discordant for kidney disease reveals DNA variants associated with diabetic nephropathy J Guo, OJL Rackham, N Sandholm, B He, AM Österholm, E Valo, ... Journal of the American Society of Nephrology 31 (2), 309-323, 2020 | 16 | 2020 |
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