| The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder GS Stewart, RS Maser, T Stankovic, DA Bressan, MI Kaplan, NGJ Jaspers, ... Cell 99 (6), 577-587, 1999 | 1261 | 1999 |
| MDC1 is a mediator of the mammalian DNA damage checkpoint GS Stewart, B Wang, CR Bignell, AMR Taylor, SJ Elledge Nature 421 (6926), 961-966, 2003 | 1150 | 2003 |
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage GS Stewart, S Panier, K Townsend, AK Al-Hakim, NK Kolas, ES Miller, ... Cell 136 (3), 420-434, 2009 | 886 | 2009 |
| Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia T Stankovic, P Weber, G Stewart, T Bedenham, J Murray, PJ Byrd, ... The Lancet 353 (9146), 26-29, 1999 | 442 | 1999 |
| 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair AT Noon, A Shibata, N Rief, M Löbrich, GS Stewart, PA Jeggo, ... Nature cell biology 12 (2), 177-184, 2010 | 412 | 2010 |
| p53 dysfunction in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative toTP53 mutation AR Pettitt, PD Sherrington, G Stewart, JC Cawley, AMR Taylor, ... Blood, The Journal of the American Society of Hematology 98 (3), 814-822, 2001 | 327 | 2001 |
| ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells M Kwok, N Davies, A Agathanggelou, E Smith, C Oldreive, E Petermann, ... Blood, The Journal of the American Society of Hematology 127 (5), 582-595, 2016 | 307 | 2016 |
| Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin C Spycher, ES Miller, K Townsend, L Pavic, NA Morrice, P Janscak, ... Journal of Cell Biology 181 (2), 227-240, 2008 | 299 | 2008 |
| PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation GE Ronson, AL Piberger, MR Higgs, AL Olsen, GS Stewart, PJ McHugh, ... Nature communications 9 (1), 746, 2018 | 229 | 2018 |
| A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses CE Lilley, MS Chaurushiya, C Boutell, S Landry, J Suh, S Panier, ... The EMBO journal 29 (5), 943-955, 2010 | 221 | 2010 |
| BOD1L is required to suppress deleterious resection of stressed replication forks MR Higgs, JJ Reynolds, A Winczura, AN Blackford, V Borel, ES Miller, ... Molecular cell 59 (3), 462-477, 2015 | 209 | 2015 |
| Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair SE Polo, AN Blackford, JR Chapman, L Baskcomb, S Gravel, A Rusch, ... Molecular cell 45 (4), 505-516, 2012 | 206 | 2012 |
| RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling GS Stewart, T Stankovic, PJ Byrd, T Wechsler, ES Miller, A Huissoon, ... Proceedings of the National Academy of Sciences 104 (43), 16910-16915, 2007 | 196 | 2007 |
| Ataxia telangiectasia mutated–deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired … T Stankovic, GS Stewart, C Fegan, P Biggs, J Last, PJ Byrd, RD Keenan, ... Blood, The Journal of the American Society of Hematology 99 (1), 300-309, 2002 | 195 | 2002 |
| Chromosome instability syndromes AMR Taylor, C Rothblum-Oviatt, NA Ellis, ID Hickson, S Meyer, ... Nature reviews Disease primers 5 (1), 64, 2019 | 194 | 2019 |
| Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation SY Lin, K Li, GS Stewart, SJ Elledge Proceedings of the National Academy of Sciences 101 (17), 6484-6489, 2004 | 180 | 2004 |
| The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells A Zlatanou, E Despras, T Braz-Petta, I Boubakour-Azzouz, C Pouvelle, ... Molecular cell 43 (4), 649-662, 2011 | 173 | 2011 |
| Microarray analysis reveals that TP53-and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in … T Stankovic, M Hubank, D Cronin, GS Stewart, D Fletcher, CR Bignell, ... Blood 103 (1), 291-300, 2004 | 150 | 2004 |
| PRMT5-dependent methylation of the TIP60 coactivator RUVBL1 is a key regulator of homologous recombination TL Clarke, MP Sanchez-Bailon, K Chiang, JJ Reynolds, J Herrero-Ruiz, ... Molecular cell 65 (5), 900-916. e7, 2017 | 147 | 2017 |
| The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression AS Turnell, GS Stewart, RJA Grand, SM Rookes, A Martin, H Yamano, ... Nature 438 (7068), 690-695, 2005 | 125 | 2005 |
Tatjana StankovicProfessor of Cancer GeneticsGeverifieerd e-mailadres voor bham.ac.uk