| Chronic peroxisome proliferator-activated receptor γ (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1 … N Petrovic, TB Walden, IG Shabalina, JA Timmons, B Cannon, ... Journal of Biological Chemistry 285 (10), 7153-7164, 2010 | 1583 | 2010 |
| UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic IG Shabalina, N Petrovic, JMA de Jong, AV Kalinovich, B Cannon, ... Cell reports 5 (5), 1196-1203, 2013 | 760 | 2013 |
| Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice D Edgar, I Shabalina, Y Camara, A Wredenberg, MA Calvaruso, ... Cell metabolism 10 (2), 131-138, 2009 | 284 | 2009 |
| Uncoupling proteins: a role in protection against reactive oxygen species—or not? B Cannon, IG Shabalina, TV Kramarova, N Petrovic, J Nedergaard Biochimica et Biophysica Acta (BBA)-Bioenergetics 1757 (5-6), 449-458, 2006 | 241 | 2006 |
| Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids IG Shabalina, A Jacobsson, B Cannon, J Nedergaard Journal of Biological Chemistry 279 (37), 38236-38248, 2004 | 197 | 2004 |
| Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen … T Panaretakis, IG Shabalina, D Grandér, MC Shoshan, JW DePierre Toxicology and applied pharmacology 173 (1), 56-64, 2001 | 187 | 2001 |
| Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARγ agonist N Petrovic, IG Shabalina, JA Timmons, B Cannon, J Nedergaard American journal of physiology-endocrinology and metabolism 295 (2), E287-E296, 2008 | 178 | 2008 |
| ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue R Westerberg, JE Månsson, V Golozoubova, IG Shabalina, EC Backlund, ... Journal of Biological Chemistry 281 (8), 4958-4968, 2006 | 172 | 2006 |
| Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents VN Anisimov, MV Egorov, MS Krasilshchikova, KG Lyamzaev, ... Aging (Albany NY) 3 (11), 1110, 2011 | 158 | 2011 |
| Ultraendurance exercise increases the production of reactive oxygen species in isolated mitochondria from human skeletal muscle K Sahlin, IG Shabalina, CM Mattsson, L Bakkman, M Fernström, ... Journal of applied physiology 108 (4), 780-787, 2010 | 158 | 2010 |
| Mitochondrial (‘mild’) uncoupling and ROS production: physiologically relevant or not? IG Shabalina, J Nedergaard Biochemical Society Transactions 39 (5), 1305-1309, 2011 | 136 | 2011 |
| SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity JP Silva, IG Shabalina, E Dufour, N Petrovic, EC Backlund, K Hultenby, ... The EMBO journal 24 (23), 4061-4070, 2005 | 124 | 2005 |
| Cidea improves the metabolic profile through expansion of adipose tissue G Abreu-Vieira, AW Fischer, C Mattsson, JM De Jong, IG Shabalina, ... Nature Communications 6 (1), 7433, 2015 | 115 | 2015 |
| Increased fatigue resistance linked to Ca2+‐stimulated mitochondrial biogenesis in muscle fibres of cold‐acclimated mice JD Bruton, J Aydin, T Yamada, IG Shabalina, N Ivarsson, SJ Zhang, ... The Journal of physiology 588 (21), 4275-4288, 2010 | 114 | 2010 |
| Uncoupling protein-1 is not leaky IG Shabalina, M Ost, N Petrovic, M Vrbacky, J Nedergaard, B Cannon Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 773-784, 2010 | 112 | 2010 |
| In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice A Logan, IG Shabalina, TA Prime, S Rogatti, AV Kalinovich, RC Hartley, ... Aging Cell 13 (4), 765-768, 2014 | 108 | 2014 |
| Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced … IG Shabalina, TV Kramarova, J Nedergaard, B Cannon Biochemical Journal 399 (3), 405-414, 2006 | 108 | 2006 |
| Cold tolerance of UCP1-ablated mice: a skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid … IG Shabalina, J Hoeks, TV Kramarova, P Schrauwen, B Cannon, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 968-980, 2010 | 107 | 2010 |
| The GPR 120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat M Schilperoort, AD van Dam, G Hoeke, IG Shabalina, A Okolo, ... EMBO molecular medicine 10 (3), e8047, 2018 | 105 | 2018 |
| Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1 IG Shabalina, MY Vyssokikh, N Gibanova, RI Csikasz, D Edgar, ... Aging (Albany NY) 9 (2), 315, 2017 | 104 | 2017 |
Jan Nedergaardprofessor of physiology, Stockholm UniversityGeverifieerd e-mailadres voor su.se
