A Computational Study of Feedback Effects on Signal Dynamics in a Mitogen‐Activated Protein Kinase (MAPK) Pathway Model AR Asthagiri, DA Lauffenburger Biotechnology Progress 17 (2), 227-239, 2001 | 262 | 2001 |
Bioengineering models of cell signaling AR Asthagiri, DA Lauffenburger Annual Review of Biomedical Engineering 2 (1), 31-53, 2000 | 226 | 2000 |
Quantitative relationship among integrin-ligand binding, adhesion, and signaling via focal adhesion kinase and extracellular signal-regulated kinase 2 AR Asthagiri, CM Nelson, AF Horwitz, DA Lauffenburger Journal of Biological Chemistry 274 (38), 27119-27127, 1999 | 135 | 1999 |
Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation JH Kim, AR Asthagiri Journal of cell science 124 (8), 1280-1287, 2011 | 126 | 2011 |
Tunable interplay between epidermal growth factor and cell–cell contact governs the spatial dynamics of epithelial growth JH Kim, K Kushiro, NA Graham, AR Asthagiri Proceedings of the National Academy of Sciences 106 (27), 11149-11153, 2009 | 84 | 2009 |
Intercellular coupling amplifies fate segregation during Caenorhabditis elegans vulval development CA Giurumescu, PW Sternberg, AR Asthagiri Proceedings of the National Academy of Sciences of the United States of …, 2006 | 69 | 2006 |
Quantitative effect of scaffold abundance on signal propagation SA Chapman, AR Asthagiri Molecular systems biology 5 (1), 2009 | 63 | 2009 |
Reprogramming directional cell motility by tuning micropattern features and cellular signals K Kushiro, S Chang, AR Asthagiri Advanced Materials 22 (40), 4516-4519, 2010 | 58 | 2010 |
The role of transient ERK2 signals in fibronectin-and insulin-mediated DNA synthesis AR Asthagiri, CA Reinhart, AF Horwitz, DA Lauffenburger Journal of cell science 113 (24), 4499-4510, 2000 | 47 | 2000 |
Collective Migration Exhibits Greater Sensitivity But Slower Dynamics of Alignment to Applied Electric Fields ML Lalli, AR Asthagiri Cellular and molecular bioengineering 8 (2), 247-257, 2015 | 42 | 2015 |
Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed … NA Graham, AR Asthagiri Journal of Biological Chemistry 279 (22), 23517-23524, 2004 | 41 | 2004 |
Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement DF Milano, NA Ngai, SK Muthuswamy, AR Asthagiri Biophysical journal 110 (8), 1886-1895, 2016 | 39 | 2016 |
Quantitatively distinct requirements for signaling-competent cell spreading on engineered versus natural adhesion ligands GP Richman, DA Tirrell, AR Asthagiri Journal of controlled release 101 (1), 3-12, 2005 | 36 | 2005 |
Modular design of micropattern geometry achieves combinatorial enhancements in cell motility K Kushiro, AR Asthagiri Langmuir 28 (9), 4357-4362, 2012 | 35 | 2012 |
Intercellular mechanotransduction during multicellular morphodynamics JH Kim, LJ Dooling, AR Asthagiri Journal of The Royal Society Interface 7 (Suppl 3), S341-S350, 2010 | 33 | 2010 |
Three-dimensional analysis of the effect of epidermal growth factor on cell-cell adhesion in epithelial cell clusters J Notbohm, JH Kim, AR Asthagiri, G Ravichandran Biophysical journal 102 (6), 1323-1330, 2012 | 30 | 2012 |
Predicting phenotypic diversity and the underlying quantitative molecular transitions CA Giurumescu, PW Sternberg, AR Asthagiri PLoS computational biology 5 (4), e1000354, 2009 | 30 | 2009 |
Resistance to signal activation governs design features of the MAP kinase signaling module S Chapman, AR Asthagiri Biotechnology and bioengineering 85 (3), 311-322, 2004 | 30 | 2004 |
A rapid and sensitive quantitative kinase activity assay using a convenient 96-well format AR Asthagiri, AF Horwitz, DA Lauffenburger Analytical biochemistry 269 (2), 342-347, 1999 | 27 | 1999 |
Cell chemotaxis on paper for diagnostics DI Walsh III, ML Lalli, JM Kassas, AR Asthagiri, SK Murthy Analytical chemistry 87 (11), 5505-5510, 2015 | 22 | 2015 |