Signalling through C-type lectin receptors: shaping immune responses TBH Geijtenbeek, SI Gringhuis Nature Reviews Immunology 9 (7), 465-479, 2009 | 1726 | 2009 |
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-κB SI Gringhuis, J den Dunnen, M Litjens, B van Het Hof, Y van Kooyk, ... Immunity 26 (5), 605-616, 2007 | 771 | 2007 |
Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk SI Gringhuis, J Den Dunnen, M Litjens, M Van Der Vlist, B Wevers, ... Nature immunology 10 (2), 203-213, 2009 | 625 | 2009 |
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome SI Gringhuis, TM Kaptein, BA Wevers, B Theelen, M Van Der Vlist, ... Nature immunology 13 (3), 246-254, 2012 | 576 | 2012 |
Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori SI Gringhuis, J Den Dunnen, M Litjens, M Van Der Vlist, TBH Geijtenbeek Nature immunology 10 (10), 1081-1088, 2009 | 534 | 2009 |
Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling G Schreibelt, G Kooij, A Reijerkerk, R Van Doorn, SI Gringhuis, ... The FASEB Journal 21 (13), 3666-3676, 2007 | 415 | 2007 |
HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells SI Gringhuis, M Van Der Vlist, LM Van Den Berg, J Den Dunnen, M Litjens, ... Nature immunology 11 (5), 419-426, 2010 | 334 | 2010 |
C-type lectin receptors in the control of T helper cell differentiation TBH Geijtenbeek, SI Gringhuis Nature Reviews Immunology 16 (7), 433-448, 2016 | 258 | 2016 |
Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45 SJ van Vliet, SI Gringhuis, TBH Geijtenbeek, Y van Kooyk Nature immunology 7 (11), 1200-1208, 2006 | 255 | 2006 |
Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization JWR Hovius, MAWP de Jong, J den Dunnen, M Litjens, E Fikrig, ... PLoS pathogens 4 (2), e31, 2008 | 226 | 2008 |
Innate signaling and regulation of dendritic cell immunity SJ Van Vliet, J den Dunnen, SI Gringhuis, TBH Geijtenbeek, Y van Kooyk Current opinion in immunology 19 (4), 435-440, 2007 | 221 | 2007 |
Innate signaling by the C-type lectin DC-SIGN dictates immune responses J Den Dunnen, SI Gringhuis, TBH Geijtenbeek Cancer Immunology, Immunotherapy 58, 1149-1157, 2009 | 215 | 2009 |
Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2 SI Gringhuis, BA Wevers, TM Kaptein, TMM van Capel, B Theelen, ... PLoS pathogens 7 (1), e1001259, 2011 | 203 | 2011 |
Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets CMS Ribeiro, R Sarrami-Forooshani, LC Setiawan, EM Zijlstra-Willems, ... Nature 540 (7633), 448-452, 2016 | 188 | 2016 |
TNF-α and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo MAWP de Jong, L de Witte, MJ Oudhoff, SI Gringhuis, P Gallay, ... The Journal of clinical investigation 118 (10), 3440-3452, 2008 | 175 | 2008 |
Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity BA Wevers, TM Kaptein, EM Zijlstra-Willems, B Theelen, T Boekhout, ... Cell host & microbe 15 (4), 494-505, 2014 | 170 | 2014 |
Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε-and CYLD-dependent Bcl3 activation SI Gringhuis, TM Kaptein, BA Wevers, AW Mesman, TBH Geijtenbeek Nature communications 5 (1), 3898, 2014 | 168 | 2014 |
Displacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in … SI Gringhuis, A Leow, EAM Papendrecht-van der Voort, PHJ Remans, ... The Journal of Immunology 164 (4), 2170-2179, 2000 | 156 | 2000 |
Antagonism of the phosphatase PP1 by the measles virus V protein is required for innate immune escape of MDA5 ME Davis, MK Wang, LJ Rennick, F Full, S Gableske, AW Mesman, ... Cell host & microbe 16 (1), 19-30, 2014 | 152 | 2014 |
Expression of the thioredoxin–thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis MM Maurice, H Nakamura, S Gringhuis, T Okamoto, S Yoshida, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1999 | 150 | 1999 |