Metal complexes for therapeutic applications J Karges, RW Stokes, SM Cohen Trends in chemistry 3 (7), 523-534, 2021 | 143 | 2021 |
Expanding medicinal chemistry into 3D space: Metallofragments as 3D scaffolds for fragment-based drug discovery CN Morrison, KE Prosser, RW Stokes, A Cordes, N Metzler-Nolte, ... Chemical science 11 (5), 1216-1225, 2020 | 141 | 2020 |
Evaluation of 3-dimensionality in approved and experimental drug space KE Prosser, RW Stokes, SM Cohen ACS medicinal chemistry letters 11 (6), 1292-1298, 2020 | 61 | 2020 |
Structure–activity relationships in metal-binding pharmacophores for influenza endonuclease CV Credille, BL Dick, CN Morrison, RW Stokes, RN Adamek, NC Wu, ... Journal of medicinal chemistry 61 (22), 10206-10217, 2018 | 57 | 2018 |
SAR exploration of tight-binding inhibitors of influenza virus PA endonuclease CV Credille, CN Morrison, RW Stokes, BL Dick, Y Feng, J Sun, Y Chen, ... Journal of medicinal chemistry 62 (21), 9438-9449, 2019 | 45 | 2019 |
Allylic Aminations with Hindered Secondary Amine Nucleophiles Catalyzed by Heterobimetallic Pd–Ti Complexes WK Walker, DL Anderson, RW Stokes, SJ Smith, DJ Michaelis Organic letters 17 (3), 752-755, 2015 | 45 | 2015 |
4-Cyanobenzenesulfonamides: amine synthesis and protecting strategy to compliment the nosyl group MA Schmidt, RW Stokes, ML Davies, F Roberts The Journal of Organic Chemistry 82 (9), 4550-4560, 2017 | 31 | 2017 |
Electrophilic activation of alkynes for enyne cycloisomerization reactions with in situ generated early/late heterobimetallic Pt–Ti catalysts MR Talley, RW Stokes, WK Walker, DJ Michaelis Dalton Transactions 45 (24), 9770-9773, 2016 | 18 | 2016 |
Direct synthesis of 5-acyl-3-oxy-4-pyrones based on acid-catalyzed acylation of enaminodiones with acylbenzotriazoles via soft enolization DL Obydennov, VV Viktorova, EV Chernyshova, AS Shirinkin, ... Synthesis 52 (15), 2267-2276, 2020 | 14 | 2020 |
Photorelease of a metal-binding pharmacophore from a Ru (ii) polypyridine complex J Karges, RW Stokes, SM Cohen Dalton Transactions 50 (8), 2757-2765, 2021 | 12 | 2021 |
Hydroxypyridinethione Inhibitors of Human Insulin‐Degrading Enzyme RN Adamek, CN Suire, RW Stokes, MK Brizuela, SM Cohen, ... ChemMedChem 16 (11), 1776-1788, 2021 | 10 | 2021 |
Exploration of the 2, 3-dihydroisoindole pharmacophore for inhibition of the influenza virus PA endonuclease D Rogolino, L Naesens, J Bartoli, M Carcelli, L De Luca, G Pelosi, ... Bioorganic chemistry 116, 105388, 2021 | 9 | 2021 |
Synthesis of chiral titanium-containing phosphinoamide ligands for enantioselective heterobimetallic catalysis CC Ence, WK Walker, RW Stokes, EE Martinez, SM Sarager, SJ Smith, ... Tetrahedron 75 (24), 3341-3347, 2019 | 8 | 2019 |
Computational prediction of the binding pose of metal-binding pharmacophores J Karges, RW Stokes, SM Cohen ACS Medicinal Chemistry Letters 13 (3), 428-435, 2022 | 7 | 2022 |
Carboxylic acid isostere derivatives of hydroxypyridinones as core scaffolds for influenza endonuclease inhibitors RW Stokes, AJ Kohlbrand, H Seo, B Sankaran, J Karges, SM Cohen ACS Medicinal Chemistry Letters 14 (1), 75-82, 2022 | 6 | 2022 |
Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants AJ Kohlbrand, RW Stokes, B Sankaran, SM Cohen Biochemistry 63 (3), 264-272, 2024 | 3 | 2024 |
Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs H Seo, AJ Kohlbrand, RW Stokes, J Chung, SM Cohen Chemical Communications 59 (16), 2283-2286, 2023 | 3 | 2023 |
Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs (vol 59, pg 2283, 2023) H Seo, AJJ Kohlbrand, RWW Stokes, J Chung, SMM Cohen CHEMICAL COMMUNICATIONS 59 (24), 3614-3614, 2023 | | 2023 |
Metal complexes for therapeutic applications:(Trends in Chemistry 3, 523–534; 2021) J Karges, RW Stokes, SM Cohen Trends in Chemistry 5 (2), 162, 2023 | | 2023 |
Further correction: Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery CN Morrison, KE Prosser, RW Stokes, A Cordes, N Metzler-Nolte, ... Chemical Science 14 (37), 10360-10362, 2023 | | 2023 |