| Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A VG Sankaran, TF Menne, J Xu, TE Akie, G Lettre, B Van Handel, ... Science 322 (5909), 1839-1842, 2008 | 1085 | 2008 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 844 | 2021 |
| Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia M Uda, R Galanello, S Sanna, G Lettre, VG Sankaran, W Chen, G Usala, ... Proceedings of the National Academy of Sciences 105 (5), 1620-1625, 2008 | 816 | 2008 |
| DNA polymorphisms at the BCL11A, HBS1L-MYB, and β-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease G Lettre, VG Sankaran, MAC Bezerra, AS Araújo, M Uda, S Sanna, A Cao, ... Proceedings of the National Academy of Sciences 105 (33), 11869-11874, 2008 | 692 | 2008 |
| Inherited causes of clonal haematopoiesis in 97,691 whole genomes AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ... Nature 586 (7831), 763-768, 2020 | 574 | 2020 |
| The polygenic and monogenic basis of blood traits and diseases D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ... Cell 182 (5), 1214-1231. e11, 2020 | 561 | 2020 |
| Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ... Cell 182 (5), 1198-1213. e14, 2020 | 522 | 2020 |
| Developmental and species-divergent globin switching are driven by BCL11A VG Sankaran, J Xu, T Ragoczy, GC Ippolito, CR Walkley, SD Maika, ... Nature 460 (7259), 1093-1097, 2009 | 489 | 2009 |
| Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics LS Ludwig, CA Lareau, JC Ulirsch, E Christian, C Muus, LH Li, K Pelka, ... Cell 176 (6), 1325-1339. e22, 2019 | 487 | 2019 |
| Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6 J Xu, VG Sankaran, M Ni, TF Menne, RV Puram, W Kim, SH Orkin Genes & development 24 (8), 783-798, 2010 | 479 | 2010 |
| Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease CR Walkley, R Qudsi, VG Sankaran, JA Perry, M Gostissa, SI Roth, ... Genes & development 22 (12), 1662-1676, 2008 | 429 | 2008 |
| The switch from fetal to adult hemoglobin VG Sankaran, SH Orkin Cold Spring Harbor perspectives in medicine 3 (1), a011643, 2013 | 423 | 2013 |
| Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains KM Ferguson, JM Kavran, VG Sankaran, E Fournier, SJ Isakoff, ... Molecular cell 6 (2), 373-384, 2000 | 418 | 2000 |
| Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia VG Sankaran, R Ghazvinian, R Do, P Thiru, JA Vergilio, AH Beggs, ... The Journal of clinical investigation 122 (7), 2439-2443, 2012 | 399 | 2012 |
| Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis RK Khajuria, M Munschauer, JC Ulirsch, C Fiorini, LS Ludwig, ... Cell 173 (1), 90-103. e19, 2018 | 382 | 2018 |
| Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing J Xu, C Peng, VG Sankaran, Z Shao, EB Esrick, BG Chong, GC Ippolito, ... Science 334 (6058), 993-996, 2011 | 381 | 2011 |
| Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells EP Mimitou, CA Lareau, KY Chen, AL Zorzetto-Fernandes, Y Hao, ... Nature biotechnology 39 (10), 1246-1258, 2021 | 375 | 2021 |
| Coronavirus disease 2019 in patients with inborn errors of immunity: an international study I Meyts, G Bucciol, I Quinti, B Neven, A Fischer, E Seoane, ... Journal of Allergy and Clinical Immunology 147 (2), 520-531, 2021 | 374 | 2021 |
| Systematic functional dissection of common genetic variation affecting red blood cell traits JC Ulirsch, SK Nandakumar, L Wang, FC Giani, X Zhang, P Rogov, ... Cell 165 (6), 1530-1545, 2016 | 359 | 2016 |
| Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation G Galarneau, CD Palmer, VG Sankaran, SH Orkin, JN Hirschhorn, ... Nature genetics 42 (12), 1049-1051, 2010 | 334 | 2010 |
Stuart OrkinGeverifieerd e-mailadres voor dfci.harvard.edu