| Cancer-associated IDH1 mutations produce 2-hydroxyglutarate L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ... Nature 462 (7274), 739-744, 2009 | 4865 | 2009 |
| Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ... New England Journal of Medicine 353 (19), 2012-2024, 2005 | 1741 | 2005 |
| Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma TF Cloughesy, AY Mochizuki, JR Orpilla, W Hugo, AH Lee, TB Davidson, ... Nature medicine 25 (3), 477-486, 2019 | 1277 | 2019 |
| Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ... Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007 | 1259 | 2007 |
| High-throughput oncogene mutation profiling in human cancer RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ... Nature genetics 39 (3), 347-351, 2007 | 1176 | 2007 |
| Intertumoral heterogeneity within medulloblastoma subgroups FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ... Cancer cell 31 (6), 737-754. e6, 2017 | 1165 | 2017 |
| The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 1076 | 2017 |
| Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 1014 | 2012 |
| Gene expression profiling of gliomas strongly predicts survival WA Freije, FE Castro-Vargas, Z Fang, S Horvath, T Cloughesy, LM Liau, ... Cancer research 64 (18), 6503-6510, 2004 | 898 | 2004 |
| Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target S Horvath, B Zhang, M Carlson, KV Lu, S Zhu, RM Felciano, MF Laurance, ... Proceedings of the National Academy of Sciences 103 (46), 17402-17407, 2006 | 767 | 2006 |
| Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma TF Cloughesy, K Yoshimoto, P Nghiemphu, K Brown, J Dang, S Zhu, ... PLoS medicine 5 (1), e8, 2008 | 679 | 2008 |
| Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment LM Liau, RM Prins, SM Kiertscher, SK Odesa, TJ Kremen, AJ Giovannone, ... Clinical Cancer Research 11 (15), 5515-5525, 2005 | 646 | 2005 |
| First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma LM Liau, K Ashkan, DD Tran, JL Campian, JE Trusheim, CS Cobbs, ... Journal of translational medicine 16, 1-9, 2018 | 595 | 2018 |
| Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme A Lai, A Tran, PL Nghiemphu, WB Pope, OE Solis, M Selch, E Filka, ... Journal of clinical oncology 29 (2), 142-148, 2011 | 569 | 2011 |
| Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG W Chen, T Cloughesy, N Kamdar, N Satyamurthy, M Bergsneider, L Liau, ... Journal of Nuclear Medicine 46 (6), 945-952, 2005 | 562 | 2005 |
| Evidence for Sequenced Molecular Evolution of IDH1 Mutant Glioblastoma From a Distinct Cell of Origin A Lai, S Kharbanda, WB Pope, A Tran, OE Solis, F Peale, WF Forrest, ... Journal of clinical oncology 29 (34), 4482-4490, 2011 | 546 | 2011 |
| Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ... Journal of Clinical Oncology 31 (23), 2927-2935, 2013 | 541 | 2013 |
| Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy RM Prins, H Soto, V Konkankit, SK Odesa, A Eskin, WH Yong, SF Nelson, ... Clinical cancer research 17 (6), 1603-1615, 2011 | 538 | 2011 |
| Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ... Nature genetics 45 (3), 253-261, 2013 | 458 | 2013 |
| Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies S Veeriah, BS Taylor, S Meng, F Fang, E Yilmaz, I Vivanco, ... Nature genetics 42 (1), 77-82, 2010 | 440 | 2010 |
Timothy CloughesyUCLAGeverifieerd e-mailadres voor mednet.ucla.edu