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Ruth Clifford
Ruth Clifford
Consultant Haematologist, University Hospital Limerick
Geverifieerd e-mailadres voor hse.ie
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Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns
A Schuh, J Becq, S Humphray, A Alexa, A Burns, R Clifford, SM Feller, ...
Blood, The Journal of the American Society of Hematology 120 (20), 4191-4196, 2012
3892012
SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage
R Clifford, T Louis, P Robbe, S Ackroyd, A Burns, AT Timbs, ...
Blood, The Journal of the American Society of Hematology 123 (7), 1021-1031, 2014
2642014
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
V Ljungström, D Cortese, E Young, T Pandzic, L Mansouri, K Plevova, ...
Blood, The Journal of the American Society of Hematology 127 (8), 1007-1016, 2016
1682016
Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL
R Guièze, P Robbe, R Clifford, S De Guibert, B Pereira, A Timbs, ...
Blood, The Journal of the American Society of Hematology 126 (18), 2110-2117, 2015
1402015
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
H Parker, MJJ Rose-Zerilli, M Larrayoz, R Clifford, J Edelmann, ...
Leukemia 30 (11), 2179-2186, 2016
852016
Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups
A Burns, R Alsolami, J Becq, B Stamatopoulos, A Timbs, D Bruce, ...
Leukemia 32 (2), 332-342, 2018
832018
Targeted deep sequencing reveals clinically relevant subclonal IgHV rearrangements in chronic lymphocytic leukemia
B Stamatopoulos, A Timbs, D Bruce, T Smith, R Clifford, P Robbe, A Burns, ...
Leukemia 31 (4), 837-845, 2017
802017
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia
SJL Knight, C Yau, R Clifford, AT Timbs, E Sadighi Akha, HM Dreau, ...
Leukemia 26 (7), 1564-1575, 2012
802012
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia
E Young, D Noerenberg, L Mansouri, V Ljungström, M Frick, LA Sutton, ...
Leukemia 31 (7), 1547-1554, 2017
762017
NCRI phase II study of CHOP in combination with ofatumumab in induction and maintenance in newly diagnosed Richter syndrome
TA Eyre, R Clifford, A Bloor, L Boyle, C Roberts, M Cabes, GP Collins, ...
British journal of haematology 175 (1), 43-54, 2016
692016
Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial
SJ Blakemore, R Clifford, H Parker, P Antoniou, E Stec-Dziedzic, ...
Leukemia 34 (7), 1760-1774, 2020
612020
Impact of isolated germline JAK2V617I mutation on human hematopoiesis
AJ Mead, O Chowdhury, C Pecquet, A Dusa, P Woll, D Atkinson, A Burns, ...
Blood, The Journal of the American Society of Hematology 121 (20), 4156-4165, 2013
552013
Diagnostic dilemmas of high‐grade transformation (Richter's syndrome) of chronic lymphocytic leukaemia: results of the phase II National Cancer Research Institute CHOP‐OR …
EJ Soilleux, A Wotherspoon, TA Eyre, R Clifford, M Cabes, AH Schuh
Histopathology 69 (6), 1066-1076, 2016
532016
The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia: results of a multicenter study
B Stamatopoulos, T Smith, E Crompot, K Pieters, R Clifford, M Mraz, ...
Clinical Cancer Research 24 (20), 5048-5057, 2018
522018
Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features
P Robbe, KE Ridout, DV Vavoulis, H Dréau, B Kinnersley, N Denny, ...
Nature genetics 54 (11), 1675-1689, 2022
482022
Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials
TK Wojdacz, HE Amarasinghe, L Kadalayil, A Beattie, J Forster, ...
Blood advances 3 (16), 2474-2481, 2019
312019
Transposon mutagenesis reveals fludarabine resistance mechanisms in chronic lymphocytic leukemia
T Pandzic, J Larsson, L He, S Kundu, K Ban, M Akhtar-Ali, AR Hellström, ...
Clinical Cancer Research 22 (24), 6217-6227, 2016
292016
Relevance of TP53 for CLL diagnostics
MA Catherwood, D Gonzalez, D Donaldson, R Clifford, K Mills, ...
Journal of clinical pathology 72 (5), 343-346, 2019
282019
Clinical‐grade validation of whole genome sequencing reveals robust detection of low‐frequency variants and copy number alterations in CLL
J Klintman, K Barmpouti, SJL Knight, P Robbe, H Dreau, R Clifford, ...
British journal of haematology 182 (3), 412-417, 2018
212018
Treatment patterns and outcomes of unfit and elderly patients with Mantle cell lymphoma unfit for standard immunochemotherapy: a UK and Ireland analysis
A Rampotas, MR Wilson, O Lomas, N Denny, H Leary, G Ferguson, ...
British Journal of Haematology 194 (2), 365-377, 2021
172021
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Artikelen 1–20