Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns A Schuh, J Becq, S Humphray, A Alexa, A Burns, R Clifford, SM Feller, ... Blood, The Journal of the American Society of Hematology 120 (20), 4191-4196, 2012 | 389 | 2012 |
SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage R Clifford, T Louis, P Robbe, S Ackroyd, A Burns, AT Timbs, ... Blood, The Journal of the American Society of Hematology 123 (7), 1021-1031, 2014 | 264 | 2014 |
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations V Ljungström, D Cortese, E Young, T Pandzic, L Mansouri, K Plevova, ... Blood, The Journal of the American Society of Hematology 127 (8), 1007-1016, 2016 | 168 | 2016 |
Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL R Guièze, P Robbe, R Clifford, S De Guibert, B Pereira, A Timbs, ... Blood, The Journal of the American Society of Hematology 126 (18), 2110-2117, 2015 | 140 | 2015 |
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia H Parker, MJJ Rose-Zerilli, M Larrayoz, R Clifford, J Edelmann, ... Leukemia 30 (11), 2179-2186, 2016 | 85 | 2016 |
Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups A Burns, R Alsolami, J Becq, B Stamatopoulos, A Timbs, D Bruce, ... Leukemia 32 (2), 332-342, 2018 | 83 | 2018 |
Targeted deep sequencing reveals clinically relevant subclonal IgHV rearrangements in chronic lymphocytic leukemia B Stamatopoulos, A Timbs, D Bruce, T Smith, R Clifford, P Robbe, A Burns, ... Leukemia 31 (4), 837-845, 2017 | 80 | 2017 |
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia SJL Knight, C Yau, R Clifford, AT Timbs, E Sadighi Akha, HM Dreau, ... Leukemia 26 (7), 1564-1575, 2012 | 80 | 2012 |
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia E Young, D Noerenberg, L Mansouri, V Ljungström, M Frick, LA Sutton, ... Leukemia 31 (7), 1547-1554, 2017 | 76 | 2017 |
NCRI phase II study of CHOP in combination with ofatumumab in induction and maintenance in newly diagnosed Richter syndrome TA Eyre, R Clifford, A Bloor, L Boyle, C Roberts, M Cabes, GP Collins, ... British journal of haematology 175 (1), 43-54, 2016 | 69 | 2016 |
Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial SJ Blakemore, R Clifford, H Parker, P Antoniou, E Stec-Dziedzic, ... Leukemia 34 (7), 1760-1774, 2020 | 61 | 2020 |
Impact of isolated germline JAK2V617I mutation on human hematopoiesis AJ Mead, O Chowdhury, C Pecquet, A Dusa, P Woll, D Atkinson, A Burns, ... Blood, The Journal of the American Society of Hematology 121 (20), 4156-4165, 2013 | 55 | 2013 |
Diagnostic dilemmas of high‐grade transformation (Richter's syndrome) of chronic lymphocytic leukaemia: results of the phase II National Cancer Research Institute CHOP‐OR … EJ Soilleux, A Wotherspoon, TA Eyre, R Clifford, M Cabes, AH Schuh Histopathology 69 (6), 1066-1076, 2016 | 53 | 2016 |
The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia: results of a multicenter study B Stamatopoulos, T Smith, E Crompot, K Pieters, R Clifford, M Mraz, ... Clinical Cancer Research 24 (20), 5048-5057, 2018 | 52 | 2018 |
Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features P Robbe, KE Ridout, DV Vavoulis, H Dréau, B Kinnersley, N Denny, ... Nature genetics 54 (11), 1675-1689, 2022 | 48 | 2022 |
Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials TK Wojdacz, HE Amarasinghe, L Kadalayil, A Beattie, J Forster, ... Blood advances 3 (16), 2474-2481, 2019 | 31 | 2019 |
Transposon mutagenesis reveals fludarabine resistance mechanisms in chronic lymphocytic leukemia T Pandzic, J Larsson, L He, S Kundu, K Ban, M Akhtar-Ali, AR Hellström, ... Clinical Cancer Research 22 (24), 6217-6227, 2016 | 29 | 2016 |
Relevance of TP53 for CLL diagnostics MA Catherwood, D Gonzalez, D Donaldson, R Clifford, K Mills, ... Journal of clinical pathology 72 (5), 343-346, 2019 | 28 | 2019 |
Clinical‐grade validation of whole genome sequencing reveals robust detection of low‐frequency variants and copy number alterations in CLL J Klintman, K Barmpouti, SJL Knight, P Robbe, H Dreau, R Clifford, ... British journal of haematology 182 (3), 412-417, 2018 | 21 | 2018 |
Treatment patterns and outcomes of unfit and elderly patients with Mantle cell lymphoma unfit for standard immunochemotherapy: a UK and Ireland analysis A Rampotas, MR Wilson, O Lomas, N Denny, H Leary, G Ferguson, ... British Journal of Haematology 194 (2), 365-377, 2021 | 17 | 2021 |