Molecular mechanisms underlying RB protein function FA Dick, SM Rubin Nature reviews Molecular cell biology 14 (5), 297-306, 2013 | 678 | 2013 |
Functionalized xenon as a biosensor MM Spence, SM Rubin, IE Dimitrov, EJ Ruiz, DE Wemmer, A Pines, ... Proceedings of the National Academy of Sciences 98 (19), 10654-10657, 2001 | 419 | 2001 |
Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release SM Rubin, AL Gall, N Zheng, NP Pavletich Cell 123 (6), 1093-1106, 2005 | 327 | 2005 |
Deciphering the retinoblastoma protein phosphorylation code SM Rubin Trends in biochemical sciences 38 (1), 12-19, 2013 | 291 | 2013 |
Cyclin D-Cdk4, 6 drives cell-cycle progression via the retinoblastoma protein’s C-terminal helix BR Topacio, E Zatulovskiy, S Cristea, S Xie, CS Tambo, SM Rubin, ... Molecular cell 74 (4), 758-770. e4, 2019 | 279 | 2019 |
Methylation of the retinoblastoma tumor suppressor by SMYD2 LA Saddic, LE West, A Aslanian, JR Yates, SM Rubin, O Gozani, J Sage Journal of Biological Chemistry 285 (48), 37733-37740, 2010 | 264 | 2010 |
Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase M Kõivomägi, E Valk, R Venta, A Iofik, M Lepiku, ERM Balog, SM Rubin, ... Nature 480 (7375), 128-131, 2011 | 261 | 2011 |
Integrating old and new paradigms of G1/S control SM Rubin, J Sage, JM Skotheim Molecular cell 80 (2), 183-192, 2020 | 220 | 2020 |
p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition KZ Guiley, JW Stevenson, K Lou, KJ Barkovich, V Kumarasamy, ... Science 366 (6471), eaaw2106, 2019 | 202 | 2019 |
Development of a functionalized xenon biosensor MM Spence, EJ Ruiz, SM Rubin, TJ Lowery, N Winssinger, PG Schultz, ... Journal of the American Chemical Society 126 (46), 15287-15294, 2004 | 191 | 2004 |
An RB-EZH2 complex mediates silencing of repetitive DNA sequences CA Ishak, AE Marshall, DT Passos, CR White, SJ Kim, MJ Cecchini, ... Molecular cell 64 (6), 1074-1087, 2016 | 177 | 2016 |
Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding JR Burke, AJ Deshong, JG Pelton, SM Rubin Journal of Biological Chemistry 285 (21), 16286-16293, 2010 | 175 | 2010 |
A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression MM Schachter, KA Merrick, S Larochelle, A Hirschi, C Zhang, KM Shokat, ... Molecular cell 50 (2), 250-260, 2013 | 166 | 2013 |
Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control JR Burke, GL Hura, SM Rubin Genes & development 26 (11), 1156-1166, 2012 | 159 | 2012 |
Multisite phosphorylation networks as signal processors for Cdk1 M Kõivomägi, M Örd, A Iofik, E Valk, R Venta, I Faustova, R Kivi, ... Nature structural & molecular biology 20 (12), 1415-1424, 2013 | 146 | 2013 |
Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy SM Rubin, SY Lee, EJ Ruiz, A Pines, DE Wemmer Journal of molecular biology 322 (2), 425-440, 2002 | 140 | 2002 |
An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein A Hirschi, M Cecchini, R Steinhardt, FA Dick, SM Rubin Biophysical Journal 98 (3), 248a, 2010 | 126 | 2010 |
Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions T Shi, RD Bunker, S Mattarocci, C Ribeyre, M Faty, H Gut, A Scrima, ... Cell 153 (6), 1340-1353, 2013 | 122 | 2013 |
Structural mechanisms of DREAM complex assembly and regulation KZ Guiley, TJ Liban, JG Felthousen, P Ramanan, L Litovchick, SM Rubin Genes & development 29 (9), 961-974, 2015 | 121 | 2015 |
Cks confers specificity to phosphorylation-dependent CDK signaling pathways DA McGrath, ERM Balog, M Kõivomägi, R Lucena, MV Mai, A Hirschi, ... Nature structural & molecular biology 20 (12), 1407-1414, 2013 | 106 | 2013 |