HIV-1 Nef targets MHC-I and CD4 for degradation via a final common β-COP–dependent pathway in T cells MR Schaefer, ER Wonderlich, JF Roeth, JA Leonard, KL Collins PLoS pathogens 4 (8), e1000131, 2008 | 195 | 2008 |
The tyrosine binding pocket in the adaptor protein 1 (AP-1) μ1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail ER Wonderlich, M Williams, KL Collins Journal of Biological Chemistry 283 (6), 3011-3022, 2008 | 112 | 2008 |
Blocking TLR7-and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection M Kader, AP Smith, C Guiducci, ER Wonderlich, D Normolle, SC Watkins, ... PLoS pathogens 9 (7), e1003530, 2013 | 74 | 2013 |
A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir CN Levy, SM Hughes, P Roychoudhury, DB Reeves, C Amstuz, H Zhu, ... Cell Reports Medicine 2 (4), 2021 | 70 | 2021 |
Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques ER Wonderlich, ZD Swan, SJ Bissel, AL Hartman, JP Carney, KJ O’Malley, ... The Journal of Immunology 198 (4), 1616-1626, 2017 | 61 | 2017 |
HIV immune evasion: disruption of antigen presentation by the HIV Nef protein ER Wonderlich, JA Leonard, KL Collins Advances in virus research 80, 103-127, 2011 | 61 | 2011 |
Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates J Corry, G Kettenburg, AA Upadhyay, M Wallace, MM Marti, ... PLoS Pathogens 18 (3), e1010395, 2022 | 47 | 2022 |
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals ER Wonderlich, K Subramanian, B Cox, A Wiegand, C Lackman-Smith, ... PLoS pathogens 15 (10), e1008074, 2019 | 43 | 2019 |
Peripheral blood biomarkers of disease outcome in a monkey model of Rift Valley fever encephalitis ER Wonderlich, AL Caroline, CM McMillen, AW Walters, DS Reed, ... Journal of virology 92 (3), 10.1128/jvi. 01662-17, 2018 | 40 | 2018 |
ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1 … ER Wonderlich, JA Leonard, DA Kulpa, KE Leopold, JM Norman, ... Journal of virology 85 (23), 12216-12226, 2011 | 40 | 2011 |
Macrophages and Myeloid Dendritic Cells Lose T Cell–Stimulating Function in Simian Immunodeficiency Virus Infection Associated with Diminished IL-12 and IFN-α Production ER Wonderlich, WC Wu, DP Normolle, SM Barratt-Boyes The Journal of Immunology 195 (7), 3284-3292, 2015 | 22 | 2015 |
Persistent accumulation of gut macrophages with impaired phagocytic function correlates with SIV disease progression in macaques ZD Swan, AL Bouwer, ER Wonderlich, SM Barratt‐Boyes European journal of immunology 47 (11), 1925-1935, 2017 | 19 | 2017 |
Macrophage accumulation in gut mucosa differentiates AIDS from chronic SIV infection in rhesus macaques ZD Swan, ER Wonderlich, SM Barratt‐Boyes European journal of immunology 46 (2), 446-454, 2016 | 19 | 2016 |
Virus-encoded TLR ligands reveal divergent functional responses of mononuclear phagocytes in pathogenic simian immunodeficiency virus infection ER Wonderlich, V Wijewardana, X Liu, SM Barratt-Boyes The Journal of Immunology 190 (5), 2188-2198, 2013 | 19 | 2013 |
Dissecting the role of dendritic cells in simian immunodeficiency virus infection and AIDS ER Wonderlich, M Kader, V Wijewardana, SM Barratt-Boyes Immunologic research 50, 228-234, 2011 | 19 | 2011 |
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection MYH Lee, AA Upadhyay, H Walum, CN Chan, RA Dawoud, C Grech, ... PLoS pathogens 17 (6), e1009674, 2021 | 14 | 2021 |
Predictors of HIV rebound differ by timing of antiretroviral therapy initiation JZ Li, M Melberg, A Kittilson, M Abdel-Mohsen, Y Li, E Aga, RJ Bosch, ... JCI insight 9 (3), e173864, 2024 | 11 | 2024 |
Inhibitors of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck block HIV-1 replication in macrophages and disrupt MHC-I downregulation LA Emert-Sedlak, O Moukha-Chafiq, H Shi, S Du, JJ Alvarado, V Pathak, ... ACS infectious diseases 8 (1), 91-105, 2022 | 11 | 2022 |
Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo NW Cummins, J Baker, R Chakraborty, PG Dean, E Garcia-Rivera, ... EClinicalMedicine 42, 2021 | 9 | 2021 |
A dendrite in every pie: myeloid dendritic cells in HIV and SIV infection ER Wonderlich, SM Barratt-Boyes Virulence 3 (7), 647-653, 2012 | 9 | 2012 |