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Luke Tweedy
Luke Tweedy
Geverifieerd e-mailadres voor glasgow.ac.uk
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Seeing around corners: Cells solve mazes and respond at a distance using attractant breakdown
L Tweedy, PA Thomason, PI Paschke, K Martin, LM Machesky, M Zagnoni, ...
Science 369 (6507), eaay9792, 2020
1572020
Self-generated chemoattractant gradients: attractant depletion extends the range and robustness of chemotaxis
L Tweedy, DA Knecht, GM Mackay, RH Insall
PLoS biology 14 (3), e1002404, 2016
1512016
Distinct cell shapes determine accurate chemotaxis
L Tweedy, B Meier, J Stephan, D Heinrich, RG Endres
Scientific reports 3 (1), 2606, 2013
862013
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions
L Fort, JM Batista, PA Thomason, HJ Spence, JA Whitelaw, L Tweedy, ...
Nature cell biology 20 (10), 1159-1171, 2018
802018
Self-generated chemotactic gradients—cells steering themselves
L Tweedy, O Susanto, RH Insall
Current opinion in cell biology 42, 46-51, 2016
642016
LPP3 mediates self-generation of chemotactic LPA gradients by melanoma cells
O Susanto, YWH Koh, N Morrice, S Tumanov, PA Thomason, M Nielson, ...
Journal of cell science 130 (20), 3455-3466, 2017
532017
Self-generated gradients yield exceptionally robust steering cues
L Tweedy, RH Insall
Frontiers in Cell and Developmental Biology 8, 133, 2020
492020
Memory improves precision of cell sensing in fluctuating environments
G Aquino, L Tweedy, D Heinrich, RG Endres
Scientific reports 4 (1), 5688, 2014
432014
The atypical MAP kinase ErkB transmits distinct chemotactic signals through a core signaling module
JME Nichols, P Paschke, S Peak-Chew, TD Williams, L Tweedy, M Skehel, ...
Developmental Cell 48 (4), 491-505. e9, 2019
342019
Steering yourself by the bootstraps: how cells create their own gradients for chemotaxis
RH Insall, P Paschke, L Tweedy
Trends in Cell Biology 32 (7), 585-596, 2022
212022
Screening by changes in stereotypical behavior during cell motility
L Tweedy, P Witzel, D Heinrich, RH Insall, RG Endres
Scientific reports 9 (1), 8784, 2019
132019
Competition between chemoattractants causes unexpected complexity and can explain negative chemotaxis
A Dowdell, PI Paschke, PA Thomason, L Tweedy, RH Insall
Current Biology 33 (9), 1704-1715. e3, 2023
102023
Simulation of melanoblast displacements reveals new features of developmental migration
P Laurent-Gengoux, V Petit, Z Aktary, S Gallagher, L Tweedy, L Machesky, ...
Development 145 (12), dev160200, 2018
92018
The Scar/WAVE complex drives normal actin protrusions without the Arp2/3 complex, but proline-rich domains are required
S Buracco, S Singh, S Claydon, P Paschke, L Tweedy, J Whitelaw, ...
bioRxiv, 2022.05. 14.491902, 2022
52022
AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/3 complex recruitment
SP Singh, P Paschke, L Tweedy, RH Insall
Frontiers in Molecular Biosciences 9, 965921, 2022
42022
Seeing around corners: Cells create chemotactic gradients to solve mazes and respond to distant cues in complex environments
L Tweedy, PA Thomason, K Martin, M Zagnoni, LM Machesky, RH Insall
bioRxiv, 836056, 2019
22019
The Chemoattractant Glorin Is Inactivated by Ester Cleavage during Early Multicellular Development of Polysphondylium pallidum
D Heinrich, R Barnett, L Tweedy, R Insall, P Stallforth, T Winckler
ACS Chemical Biology 13 (6), 1506-1513, 2018
12018
Meinhart Simulations on an Evolving Line
L Tweedy
Technical Report, Cside 2018 Supplementary Notes, 2018
12018
Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains
S Buracco, H Döring, S Engelbart, SP Singh, P Paschke, J Whitelaw, ...
Current Biology 34 (19), 4436-4451. e9, 2024
2024
A Reliable System for Quantitative G-Protein Activation Imaging in Cancer Cells
E Mandrou, PA Thomason, PI Paschke, NR Paul, L Tweedy, RH Insall
Cells 13 (13), 1114, 2024
2024
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Artikelen 1–20