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Joseph E Powell
Joseph E Powell
Garvan Institute of Medical Research and University of New South Wales
Geverifieerd e-mailadres voor garvan.org.au
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Biological insights from 108 schizophrenia-associated genetic loci
C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ...
Nature 511 (7510), 421-427, 2014
77332014
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
Nature medicine 26 (5), 681-687, 2020
30202020
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
29302018
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell 181 (5), 1016-1035. e19, 2020
24932020
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Z Zhu, F Zhang, H Hu, A Bakshi, MR Robinson, JE Powell, ...
Nature genetics 48 (5), 481-487, 2016
24232016
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
21962014
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
19382013
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
1671*2021
A single-cell and spatially resolved atlas of human breast cancers
SZ Wu, G Al-Eryani, DL Roden, S Junankar, K Harvey, A Andersson, ...
Nature genetics 53 (9), 1334-1347, 2021
9812021
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ...
Nature communications 9 (1), 2941, 2018
8092018
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ...
The EMBO journal 39 (19), e104063, 2020
752*2020
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ...
Nature genetics 51 (2), 245-257, 2019
7142019
The transcriptional landscape of age in human peripheral blood
MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ...
Nature communications 6 (1), 8570, 2015
6792015
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
601*2021
FTO genotype is associated with phenotypic variability of body mass index
J Yang, RJF Loos, JE Powell, SE Medland, EK Speliotes, DI Chasman, ...
Nature 490 (7419), 267-272, 2012
5172012
An integrated cell atlas of the lung in health and disease
L Sikkema, C Ramírez-Suástegui, DC Strobl, TE Gillett, L Zappia, ...
Nature medicine 29 (6), 1563-1577, 2023
434*2023
Benchmarking of cell type deconvolution pipelines for transcriptomics data
F Avila Cobos, J Alquicira-Hernandez, JE Powell, P Mestdagh, ...
Nature communications 11 (1), 5650, 2020
4022020
Reconciling the analysis of IBD and IBS in complex trait studies
JE Powell, PM Visscher, ME Goddard
Nature Reviews Genetics 11 (11), 800-805, 2010
4002010
scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data
J Alquicira-Hernandez, A Sathe, HP Ji, Q Nguyen, JE Powell
Genome biology 20, 1-17, 2019
3812019
Signatures of negative selection in the genetic architecture of human complex traits
J Zeng, R De Vlaming, Y Wu, MR Robinson, LR Lloyd-Jones, L Yengo, ...
Nature genetics 50 (5), 746-753, 2018
3742018
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Artikelen 1–20