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Chelsea R. Thorn
Chelsea R. Thorn
Principal Scientist, Genentech - Synthetic Molecule Pharmaceutical Science
Geverifieerd e-mailadres voor gene.com
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Efficacy of poly-lactic-co-glycolic acid micro-and nanoparticles of ciprofloxacin against bacterial biofilms
N Thomas, C Thorn, K Richter, B Thierry, C Prestidge
Journal of Pharmaceutical Sciences 105 (10), 3115-3122, 2016
602016
Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis‐Related Pseudomonas aeruginosa Biofilms
CR Thorn, CS Carvalho‐Wodarz, JC Horstmann, CM Lehr, CA Prestidge, ...
Small 17 (24), 2100531, 2021
572021
Enhancing the therapeutic use of biofilm-dispersing enzymes with smart drug delivery systems
CR Thorn, PL Howell, DJ Wozniak, CA Prestidge, N Thomas
Advanced Drug Delivery Reviews 179, 113916, 2021
532021
Nano-fats for bugs: The benefits of lipid nanoparticles for antimicrobial therapy
CR Thorn, N Thomas, BJ Boyd, CA Prestidge
Drug Delivery and Translational Research 11, 1598-1624, 2021
492021
Bacterial lipase triggers the release of antibiotics from digestible liquid crystal nanoparticles
CR Thorn, AJ Clulow, BJ Boyd, CA Prestidge, N Thomas
Journal of Controlled Release 319, 168-182, 2020
472020
Enzyme responsive copolymer micelles enhance the anti-biofilm efficacy of the antiseptic chlorhexidine
YN Albayaty, N Thomas, M Jambhrunkar, M Al-Hawwas, A Kral, CR Thorn, ...
International Journal of Pharmaceutics 566, 329-341, 2019
382019
The journey of a lifetime—development of Pfizer’s COVID-19 vaccine
CR Thorn, D Sharma, R Combs, S Bhujbal, J Romine, X Zheng, ...
Current opinion in biotechnology 78, 102803, 2022
342022
Protective liquid crystal nanoparticles for targeted delivery of PslG: a biofilm dispersing enzyme
CR Thorn, D Raju, I Lacdao, S Gilbert, P Sivarajah, PL Howell, ...
ACS Infectious Diseases 7 (8), 2102-2115, 2021
342021
Testing of aerosolized ciprofloxacin nanocarriers on cystic fibrosis airway cells infected with P. aeruginosa biofilms
J Juntke, X Murgia, N Günday Türeli, AE Türeli, CR Thorn, M Schneider, ...
Drug delivery and translational research 11 (4), 1752-1765, 2021
252021
Pseudomonas Infection Responsive Liquid Crystals for Glycoside Hydrolase and Antibiotic Combination
CR Thorn, CA Prestidge, BJ Boyd, N Thomas
ACS Applied Bio Materials 1 (2), 281-288, 2018
212018
A translational framework to DELIVER nanomedicines to the clinic
P Joyce, CJ Allen, MJ Alonso, M Ashford, MS Bradbury, M Germain, ...
Nature Nanotechnology 19 (11), 1597-1611, 2024
202024
Antibiotic resistance and tolerance: What can drug delivery do against this global threat?
J Aparicio-Blanco, N Vishwakarma, CM Lehr, CA Prestidge, N Thomas, ...
Drug Delivery and Translational Research 14 (6), 1725-1734, 2024
152024
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells in vitro
JC Horstmann, CR Thorn, P Carius, F Graef, X Murgia, ...
Frontiers in Bioengineering and Biotechnology 9, 643491, 2021
132021
Liquid Crystal Nanoparticles Enhance Tobramycin Efficacy in a Murine Model of Pseudomonas aeruginosa Biofilm Wound Infection
CR Thorn, A Wignall, Z Kopecki, A Kral, CA Prestidge, N Thomas
ACS Infectious Diseases 8 (4), 841-854, 2022
122022
Liquid crystal nanoparticle platform for increased efficacy of cationic antimicrobials against biofilm infections
CR Thorn, Z Kopecki, A Wignall, A Kral, CA Prestidge, N Thomas
Nanomedicine: Nanotechnology, Biology and Medicine 42, 102536, 2022
102022
A Custom-Made Device for Reproducibly Depositing Pre-metered Doses of Nebulized Drugs on Pulmonary Cells.
JC Horstmann, CR Thorn, P Carius, F Graef, X Murgia, ...
Frontiers, 2021
12021
Antimicrobial compositions and methods of use
C Thorn, N Thomas, C Prestidge
US Patent App. 18/031,762, 2023
2023
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Artikelen 1–17