Identification of hepatoprotective flavonolignans from silymarin SJ Polyak, C Morishima, V Lohmann, S Pal, DYW Lee, Y Liu, TN Graf, ... Proceedings of the national academy of sciences 107 (13), 5995-5999, 2010 | 409 | 2010 |
Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum) NC Kim, TN Graf, CM Sparacino, MC Wani, ME Wall Organic & biomolecular chemistry 1 (10), 1684-1689, 2003 | 372 | 2003 |
Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells PR Davis-Searles, Y Nakanishi, NC Kim, TN Graf, NH Oberlies, MC Wani, ... Cancer research 65 (10), 4448-4457, 2005 | 325 | 2005 |
Multiple effects of silymarin on the hepatitis C virus lifecycle J Wagoner, A Negash, OJ Kane, LE Martinez, Y Nahmias, N Bourne, ... Hepatology 51 (6), 1912-1921, 2010 | 307 | 2010 |
Synergy-Directed Fractionation of Botanical Medicines: A Case Study with Goldenseal (Hydrastis canadensis) HA Junio, AA Sy-Cordero, KA Ettefagh, JT Burns, KT Micko, TN Graf, ... Journal of natural products 74 (7), 1621-1629, 2011 | 198 | 2011 |
Silymarin inhibits in vitro T-cell proliferation and cytokine production in hepatitis C virus infection C Morishima, MC Shuhart, CC Wang, DM Paschal, MC Apodaca, Y Liu, ... Gastroenterology 138 (2), 671-681. e2, 2010 | 174 | 2010 |
Human sulfite oxidase R160Q: identification of the mutation in a sulfite oxidase-deficient patient and expression and characterization of the mutant enzyme RM Garrett, JL Johnson, TN Graf, A Feigenbaum, KV Rajagopalan Proceedings of the National Academy of Sciences 95 (11), 6394-6398, 1998 | 167 | 1998 |
Cytotoxic and Antimicrobial Constituents of the Bark of Diospyros maritima Collected in Two Geographical Locations in Indonesia JQ Gu, TN Graf, D Lee, HB Chai, Q Mi, LBS Kardono, FM Setyowati, ... Journal of Natural Products 67 (7), 1156-1161, 2004 | 130 | 2004 |
Optimization of expression of human sulfite oxidase and its molybdenum domain CA Temple, TN Graf, KV Rajagopalan Archives of Biochemistry and Biophysics 383 (2), 281-287, 2000 | 130 | 2000 |
HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case JG Napolitano, DC Lankin, TN Graf, JB Friesen, SN Chen, JB McAlpine, ... The Journal of organic chemistry 78 (7), 2827-2839, 2013 | 116 | 2013 |
Flavonolignans from Aspergillus iizukae, a Fungal Endophyte of Milk Thistle (Silybum marianum) T El-Elimat, HA Raja, TN Graf, SH Faeth, NB Cech, NH Oberlies Journal of natural products 77 (2), 193-199, 2014 | 114 | 2014 |
The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids L Flores-Bocanegra, HA Raja, TN Graf, M Augustinović, ED Wallace, ... Journal of natural products 83 (7), 2165-2177, 2020 | 112 | 2020 |
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions DA Todd, JJ Kellogg, ED Wallace, M Khin, L Flores-Bocanegra, RS Tanna, ... Scientific reports 10 (1), 19158, 2020 | 111 | 2020 |
Structural insights into sulfite oxidase deficiency E Karakas, HL Wilson, TN Graf, S Xiang, S Jaramillo-Busquets, ... Journal of Biological Chemistry 280 (39), 33506-33515, 2005 | 103 | 2005 |
Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation J Wagoner, C Morishima, TN Graf, NH Oberlies, E Teissier, EI Pécheur, ... PLoS One 6 (1), e16464, 2011 | 101 | 2011 |
Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention TN Graf, MC Wani, R Agarwal, DJ Kroll, NH Oberlies Planta medica 73 (14), 1495-1501, 2007 | 96 | 2007 |
A Hexacyclic ent-Trachylobane Diterpenoid Possessing an Oxetane Ring from Mitrephora glabra C Li, D Lee, TN Graf, SS Phifer, Y Nakanishi, JP Burgess, S Riswan, ... Organic letters 7 (25), 5709-5712, 2005 | 92 | 2005 |
Ethanolic Echinacea purpurea extracts contain a mixture of cytokine-suppressive and cytokine-inducing compounds, including some that originate from endophytic bacteria DA Todd, TV Gulledge, ER Britton, M Oberhofer, M Leyte-Lugo, ... PloS one 10 (5), e0124276, 2015 | 91 | 2015 |
Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure–activity relationships S Ayers, TN Graf, AF Adcock, DJ Kroll, S Matthew, EJ Carcache de Blanco, ... Journal of natural products 74 (5), 1126-1131, 2011 | 86 | 2011 |
Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris T El‐Elimat, M Figueroa, HA Raja, TN Graf, SM Swanson, JO Falkinham III, ... European journal of organic chemistry 2015 (1), 109-121, 2015 | 83 | 2015 |