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Alexander Guzzetta
Alexander Guzzetta
University of Chicago
Verifisert e-postadresse på uchicagomedicine.org
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Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation
L Zhou, J Liu, M Xiang, P Olson, A Guzzetta, K Zhang, IP Moskowitz, L Xie
Proceedings of the National Academy of Sciences 114 (8), E1422-E1431, 2017
812017
Hedgehog–FGF signaling axis patterns anterior mesoderm during gastrulation
A Guzzetta, M Koska, M Rowton, KR Sullivan, J Jacobs-Li, J Kweon, ...
Proceedings of the National Academy of Sciences 117 (27), 15712-15723, 2020
372020
Control of cardiomyocyte differentiation timing by intercellular signaling pathways
M Rowton, A Guzzetta, AB Rydeen, IP Moskowitz
Seminars in cell & developmental biology 118, 94-106, 2021
362021
Hedgehog signaling controls progenitor differentiation timing during heart development
M Rowton, AD Hoffmann, JD Steimle, XH Yang, A Guzzetta, S Lazarevic, ...
bioRxiv, 2018
7*2018
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
M Rowton, C Perez-Cervantes, S Hur, J Jacobs-Li, E Lu, N Deng, ...
Developmental cell 57 (18), 2181-2203. e9, 2022
62022
Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection
JH Chen, P Landback, D Arsala, A Guzzetta, S Xia, J Atlas, D Sosa, ...
Genome Research, gr. 279498.124, 2025
42025
The three-dimensional genome drives the evolution of asymmetric gene duplicates via enhancer capture-divergence
UJ Lee, D Arsala, S Xia, C Li, M Ali, N Svetec, CB Langer, DR Sobreira, ...
Science Advances 10 (51), eadn6625, 2024
12024
Century-scale Archival Sequencing of Colorectal Cancer Through a Shifting Disease Landscape
A Guzzetta, D Witonsky, S Ramachandran, C Weber, M Raghavan, ...
LABORATORY INVESTIGATION 104 (3), S1785-S1786, 2024
2024
A Hedgehog-signaling Dependent Gene Regulatory Network Directly Delays Second Heart Field Differentiation to Prevent Congenital Heart Disease
M Rowton, A Rydeen, PC Carlos, N Deng, E Lu, J Jacobs-Li, A Hoffmann, ...
Circulation Research 127 (Suppl_1), A541-A541, 2020
2020
A Hedgehog-Fgf Signaling Cascade Patterns the Anterior-Posterior Axis During Embryonic Development
A Guzzetta
The University of Chicago, 2019
2019
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Artikler 1–10