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John Reyes Ussher
John Reyes Ussher
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta
Verifisert e-postadresse på ualberta.ca
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Myocardial fatty acid metabolism in health and disease
GD Lopaschuk, JR Ussher, CDL Folmes, JS Jaswal, WC Stanley
Physiological Reviews 90 (1), 207-258, 2010
25062010
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ...
Cell metabolism 7 (1), 45-56, 2008
22042008
Cardiovascular Biology of the Incretin System
JR Ussher, DJ Drucker
Endocrine Reviews, 2012
6762012
Targeting fatty acid and carbohydrate oxidation-A novel therapeutic intervention in the ischemic and failing heart
JS Jaswal, W Keung, W Wang, JR Ussher, GD Lopaschuk
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2011
4972011
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption
JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ...
Diabetes 59 (10), 2453-2464, 2010
4182010
Cardiovascular actions of incretin-based therapies
JR Ussher, DJ Drucker
Circulation research 114 (11), 1788-1803, 2014
4012014
The emerging role of metabolomics in the diagnosis and prognosis of cardiovascular disease
JR Ussher, S Elmariah, RE Gerszten, JRB Dyck
Journal of the American College of Cardiology 68 (25), 2850-2870, 2016
3522016
Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy
L Zhang, JS Jaswal, JR Ussher, S Sankaralingam, C Wagg, M Zaugg, ...
Circulation: Heart Failure 6 (5), 1039-1048, 2013
2962013
Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action
JR Ussher, DJ Drucker
Nature reviews cardiology 20 (7), 463-474, 2023
2322023
Gut microbiota metabolism of L-carnitine and cardiovascular risk
JR Ussher, GD Lopaschuk, A Arduini
Atherosclerosis 231 (2), 456-461, 2013
2232013
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury
JR Ussher, W Wang, M Gandhi, W Keung, V Samokhvalov, T Oka, ...
Cardiovascular research 94 (2), 359-369, 2012
2032012
Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
R Basu, GY Oudit, X Wang, L Zhang, JR Ussher, GD Lopaschuk, Z Kassiri
American Journal of Physiology-Heart and Circulatory Physiology 297 (6 …, 2009
1942009
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency
KL Ho, L Zhang, C Wagg, R Al Batran, K Gopal, J Levasseur, T Leone, ...
Cardiovascular research 115 (11), 1606-1616, 2019
1832019
Lipotoxicity in obesity and diabetes-related cardiac dysfunction
I Zlobine, K Gopal, JR Ussher
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016
1832016
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure
GM Uddin, L Zhang, S Shah, A Fukushima, CS Wagg, K Gopal, ...
Cardiovascular diabetology 18, 1-12, 2019
1572019
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
L Zhang, JR Ussher, T Oka, VJJ Cadete, C Wagg, GD Lopaschuk
Cardiovascular research 89 (1), 148-156, 2011
1552011
Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice
W Keung, JR Ussher, JS Jaswal, M Raubenheimer, VHM Lam, CS Wagg, ...
Diabetes 62 (3), 711-720, 2013
1492013
Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
JR Ussher, TR Koves, JS Jaswal, L Zhang, O Ilkayeva, JRB Dyck, ...
Diabetes 58 (8), 1766-1775, 2009
1462009
TCF1 links GIPR signaling to the control of beta cell function and survival
JE Campbell, JR Ussher, EE Mulvihill, J Kolic, LL Baggio, X Cao, Y Liu, ...
Nature medicine 22 (1), 84-90, 2016
1412016
Evolving concepts of myocardial energy metabolism: more than just fats and carbohydrates
GD Lopaschuk, JR Ussher
Circulation Research 119 (11), 1173-1176, 2016
1402016
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Artikler 1–20