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Killian Hurley
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Characterization of the inflammatory response to severe COVID-19 illness
OJ McElvaney, NL McEvoy, OF McElvaney, TP Carroll, MP Murphy, ...
American journal of respiratory and critical care medicine 202 (6), 812-821, 2020
7152020
Differentiation of human pluripotent stem cells into functional lung alveolar epithelial cells
A Jacob, M Morley, F Hawkins, KB McCauley, JC Jean, H Heins, CL Na, ...
Cell stem cell 21 (4), 472-488. e10, 2017
5102017
Outcome of hospitalization for COVID-19 in patients with interstitial lung disease. An international multicenter study
TM Drake, AB Docherty, EM Harrison, JK Quint, H Adamali, S Agnew, ...
American journal of respiratory and critical care medicine 202 (12), 1656-1665, 2020
2402020
The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity
DA Bergin, EP Reeves, K Hurley, R Wolfe, R Jameel, S Fitzgerald, ...
Science translational medicine 6 (217), 217ra1-217ra1, 2014
1892014
Alpha-1 antitrypsin: a potent anti-inflammatory and potential novel therapeutic agent
DA Bergin, K Hurley, NG McElvaney, EP Reeves
Archivum immunologiae et therapiae experimentalis 60, 81-97, 2012
1592012
Reconstructed single-cell fate trajectories define lineage plasticity windows during differentiation of human PSC-derived distal lung progenitors
K Hurley, J Ding, C Villacorta-Martin, MJ Herriges, A Jacob, M Vedaie, ...
Cell stem cell 26 (4), 593-608. e8, 2020
1292020
Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis
DA Bergin, K Hurley, A Mehta, S Cox, D Ryan, SJ O’Neill, EP Reeves, ...
Journal of inflammation research, 1-11, 2013
942013
Identification of patient information corruption in the intensive care unit: using a scoring tool to direct quality improvements in handover
BW Pickering, K Hurley, B Marsh
Critical care medicine 37 (11), 2905-2912, 2009
942009
An integrated multidisciplinary model of COVID-19 recovery care
H O’Brien, MJ Tracey, C Ottewill, ME O’Brien, RK Morgan, RW Costello, ...
Irish Journal of Medical Science (1971-) 190, 461-468, 2021
792021
Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19)
DJ Ryan, S Toomey, SF Madden, M Casey, OS Breathnach, PG Morris, ...
Thorax 76 (1), 86-88, 2021
742021
Alpha-1 antitrypsin augmentation therapy corrects accelerated neutrophil apoptosis in deficient individuals
K Hurley, N Lacey, CA O’Dwyer, DA Bergin, OJ McElvaney, ME O’Brien, ...
The Journal of Immunology 193 (8), 3978-3991, 2014
742014
CoSpar identifies early cell fate biases from single-cell transcriptomic and lineage information
SW Wang, MJ Herriges, K Hurley, DN Kotton, AM Klein
Nature Biotechnology 40 (7), 1066-1074, 2022
702022
The BLT1 inhibitory function of α-1 antitrypsin augmentation therapy disrupts leukotriene B4 neutrophil signaling
CA O’Dwyer, ME O’Brien, MR Wormald, MM White, N Banville, K Hurley, ...
The Journal of Immunology 195 (8), 3628-3641, 2015
702015
Precise targeting of miRNA sites restores CFTR activity in CF bronchial epithelial cells
C De Santi, EF Fernández, R Gaul, S Vencken, A Glasgow, IK Oglesby, ...
Molecular Therapy 28 (4), 1190-1199, 2020
562020
Heterogeneity in human induced pluripotent stem cell–derived alveolar epithelial type II cells revealed with ABCA3/SFTPC reporters
YL Sun, K Hurley, C Villacorta-Martin, J Huang, A Hinds, K Gopalan, ...
American Journal of Respiratory Cell and Molecular Biology 65 (4), 442-460, 2021
292021
A multimodal iPSC platform for cystic fibrosis drug testing
A Berical, RE Lee, J Lu, ML Beermann, JA Le Suer, A Mithal, D Thomas, ...
Nature Communications 13 (1), 4270, 2022
262022
A highly phenotyped open access repository of alpha-1 antitrypsin deficiency pluripotent stem cells
JE Kaserman, K Hurley, M Dodge, C Villacorta-Martin, M Vedaie, JC Jean, ...
Stem Cell Reports 15 (1), 242-255, 2020
252020
Tumor necrosis factor-α driven inflammation in alpha-1 antitrypsin deficiency: A new model of pathogenesis and treatment
K Hurley, EP Reeves, TP Carroll, NG McElvaney
Expert review of respiratory medicine 10 (2), 207-222, 2016
192016
Modified Brixia chest X‐ray severity scoring system and correlation with intubation, non‐invasive ventilation and death in a hospitalised COVID‐19 cohort
M Hanley, C Brosnan, D O’Neill, N Ni Mhuircheartaigh, M Logan, ...
Journal of Medical Imaging and Radiation Oncology 66 (6), 761-767, 2022
122022
Lung organoids and other preclinical models of pulmonary fibrosis
IK Oglesby, A Schweikert, B Fox, C Redmond, SC Donnelly, K Hurley
QJM: An International Journal of Medicine 114 (3), 167-173, 2021
102021
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Artikler 1–20