Characterization of the inflammatory response to severe COVID-19 illness OJ McElvaney, NL McEvoy, OF McElvaney, TP Carroll, MP Murphy, ... American journal of respiratory and critical care medicine 202 (6), 812-821, 2020 | 715 | 2020 |
Differentiation of human pluripotent stem cells into functional lung alveolar epithelial cells A Jacob, M Morley, F Hawkins, KB McCauley, JC Jean, H Heins, CL Na, ... Cell stem cell 21 (4), 472-488. e10, 2017 | 510 | 2017 |
Outcome of hospitalization for COVID-19 in patients with interstitial lung disease. An international multicenter study TM Drake, AB Docherty, EM Harrison, JK Quint, H Adamali, S Agnew, ... American journal of respiratory and critical care medicine 202 (12), 1656-1665, 2020 | 240 | 2020 |
The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity DA Bergin, EP Reeves, K Hurley, R Wolfe, R Jameel, S Fitzgerald, ... Science translational medicine 6 (217), 217ra1-217ra1, 2014 | 189 | 2014 |
Alpha-1 antitrypsin: a potent anti-inflammatory and potential novel therapeutic agent DA Bergin, K Hurley, NG McElvaney, EP Reeves Archivum immunologiae et therapiae experimentalis 60, 81-97, 2012 | 159 | 2012 |
Reconstructed single-cell fate trajectories define lineage plasticity windows during differentiation of human PSC-derived distal lung progenitors K Hurley, J Ding, C Villacorta-Martin, MJ Herriges, A Jacob, M Vedaie, ... Cell stem cell 26 (4), 593-608. e8, 2020 | 129 | 2020 |
Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis DA Bergin, K Hurley, A Mehta, S Cox, D Ryan, SJ O’Neill, EP Reeves, ... Journal of inflammation research, 1-11, 2013 | 94 | 2013 |
Identification of patient information corruption in the intensive care unit: using a scoring tool to direct quality improvements in handover BW Pickering, K Hurley, B Marsh Critical care medicine 37 (11), 2905-2912, 2009 | 94 | 2009 |
An integrated multidisciplinary model of COVID-19 recovery care H O’Brien, MJ Tracey, C Ottewill, ME O’Brien, RK Morgan, RW Costello, ... Irish Journal of Medical Science (1971-) 190, 461-468, 2021 | 79 | 2021 |
Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19) DJ Ryan, S Toomey, SF Madden, M Casey, OS Breathnach, PG Morris, ... Thorax 76 (1), 86-88, 2021 | 74 | 2021 |
Alpha-1 antitrypsin augmentation therapy corrects accelerated neutrophil apoptosis in deficient individuals K Hurley, N Lacey, CA O’Dwyer, DA Bergin, OJ McElvaney, ME O’Brien, ... The Journal of Immunology 193 (8), 3978-3991, 2014 | 74 | 2014 |
CoSpar identifies early cell fate biases from single-cell transcriptomic and lineage information SW Wang, MJ Herriges, K Hurley, DN Kotton, AM Klein Nature Biotechnology 40 (7), 1066-1074, 2022 | 70 | 2022 |
The BLT1 inhibitory function of α-1 antitrypsin augmentation therapy disrupts leukotriene B4 neutrophil signaling CA O’Dwyer, ME O’Brien, MR Wormald, MM White, N Banville, K Hurley, ... The Journal of Immunology 195 (8), 3628-3641, 2015 | 70 | 2015 |
Precise targeting of miRNA sites restores CFTR activity in CF bronchial epithelial cells C De Santi, EF Fernández, R Gaul, S Vencken, A Glasgow, IK Oglesby, ... Molecular Therapy 28 (4), 1190-1199, 2020 | 56 | 2020 |
Heterogeneity in human induced pluripotent stem cell–derived alveolar epithelial type II cells revealed with ABCA3/SFTPC reporters YL Sun, K Hurley, C Villacorta-Martin, J Huang, A Hinds, K Gopalan, ... American Journal of Respiratory Cell and Molecular Biology 65 (4), 442-460, 2021 | 29 | 2021 |
A multimodal iPSC platform for cystic fibrosis drug testing A Berical, RE Lee, J Lu, ML Beermann, JA Le Suer, A Mithal, D Thomas, ... Nature Communications 13 (1), 4270, 2022 | 26 | 2022 |
A highly phenotyped open access repository of alpha-1 antitrypsin deficiency pluripotent stem cells JE Kaserman, K Hurley, M Dodge, C Villacorta-Martin, M Vedaie, JC Jean, ... Stem Cell Reports 15 (1), 242-255, 2020 | 25 | 2020 |
Tumor necrosis factor-α driven inflammation in alpha-1 antitrypsin deficiency: A new model of pathogenesis and treatment K Hurley, EP Reeves, TP Carroll, NG McElvaney Expert review of respiratory medicine 10 (2), 207-222, 2016 | 19 | 2016 |
Modified Brixia chest X‐ray severity scoring system and correlation with intubation, non‐invasive ventilation and death in a hospitalised COVID‐19 cohort M Hanley, C Brosnan, D O’Neill, N Ni Mhuircheartaigh, M Logan, ... Journal of Medical Imaging and Radiation Oncology 66 (6), 761-767, 2022 | 12 | 2022 |
Lung organoids and other preclinical models of pulmonary fibrosis IK Oglesby, A Schweikert, B Fox, C Redmond, SC Donnelly, K Hurley QJM: An International Journal of Medicine 114 (3), 167-173, 2021 | 10 | 2021 |