J. Silvio Gutkind, Ph.D.

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Panomwat AmornphimolthamVerifisert e-postadresse på mahidol.ac.th
James RuslingPaul Krenicki Professor of Chemistry, Professor of SurgeryVerifisert e-postadresse på uconn.edu
Piero CrespoIBBTEC, CSICVerifisert e-postadresse på unican.es
Ramiro Iglesias-BartolomeNIHVerifisert e-postadresse på mail.nih.gov
Zhiyong WangVerifisert e-postadresse på d.mbox.nagoya-u.ac.jp
Lynn Vitale-CrossNational Institutes of healthVerifisert e-postadresse på mail.nih.gov
Silvia MontanerProfessorVerifisert e-postadresse på umaryland.edu
Joseph CalifanoProfessor, Department of Surgery, University of California, San DiegoVerifisert e-postadresse på ucsd.edu
Ashwinkumar BhirdeStaff Fellow, FDAVerifisert e-postadresse på fda.hhs.gov
Shigetomo Fukuhara日本医科大学先端医学研究所病態解析学部門Verifisert e-postadresse på nms.ac.jp
jose pedro vaqueUniversity of CantabriaVerifisert e-postadresse på unican.es
Julie GavardCNRSVerifisert e-postadresse på inserm.fr
Juan Luis Callejas-ValeraPrimity BioVerifisert e-postadresse på primitybio.com
Ezra CohenUniversity of California San DiegoVerifisert e-postadresse på health.ucsd.edu
Nadia ArangUniversity of California San FranciscoVerifisert e-postadresse på ucsf.edu
Rogerio M. CastilhoProfessor, University of Michigan, School of DentistryVerifisert e-postadresse på umich.edu
José Vázquez-PradoProfessor of Pharmacology, CinvestavVerifisert e-postadresse på cinvestav.mx
Constantinos MikelisDepartment of Pharmacy, University of PatrasVerifisert e-postadresse på upatras.gr
Roberto WeigertSenior Investigator, National Cancer Institute, National Institutes of HealthVerifisert e-postadresse på mail.nih.gov
Colleen L. DoçiMarian University IndianapolisVerifisert e-postadresse på marian.edu

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J. Silvio Gutkind, Ph.D.

Andre navnSilvio Gutkind, J. Sylvio Gutkind

UCSD, Distinguished Professor and Chair, Dept. Pharmacology, AD Basic Science Moores Cancer Center

Verifisert e-postadresse på ucsd.edu - Startside

cell signaling G proteins GPCRs cancer precision immunotherapy


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The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway OA Coso, M Chiariello, JC Yu, H Teramoto, P Crespo, N Xu, T Miki, ... Cell 81 (7), 1137-1146, 1995	2139	1995
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate O Cuvillier, G Pirianov, B Kleuser, PG Vanek, OA Coso, JS Gutkind, ... Nature 381 (6585), 800-803, 1996	1942	1996
G-protein-coupled receptors and cancer RT Dorsam, JS Gutkind Nature reviews cancer 7 (2), 79-94, 2007	1784	2007
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. S Miyamoto, H Teramoto, OA Coso, JS Gutkind, PD Burbelo, SK Akiyama, ... The Journal of cell biology 131 (3), 791-805, 1995	1534	1995
G-protein-coupled receptors and signaling networks: emerging paradigms MJ Marinissen, JS Gutkind Trends in pharmacological sciences 22 (7), 368-376, 2001	1484	2001
VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin J Gavard, JS Gutkind Nature cell biology 8 (11), 1223-1234, 2006	1270	2006
Prostaglandin E₂ Promotes Colon Cancer Cell Growth Through a G_s-Axin-β-Catenin Signaling Axis MD Castellone, H Teramoto, BO Williams, KM Druey, JS Gutkind Science 310 (5753), 1504-1510, 2005	1141	2005
Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits P Crespo, N Xu, WF Simonds, JS Gutkind Nature 369 (6479), 418-420, 1994	1083	1994
The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades JS Gutkind Journal of Biological Chemistry 273 (4), 1839-1842, 1998	1038	1998
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator C Bais, B Santomasso, O Coso, L Arvanitakis, EG Raaka, JS Gutkind, ... Nature 391 (6662), 86-89, 1998	1035	1998
Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery AA Bhirde, V Patel, J Gavard, G Zhang, AA Sousa, A Masedunskas, ... ACS nano 3 (2), 307-316, 2009	1029	2009
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. S Miyamoto, H Teramoto, JS Gutkind, KM Yamada The Journal of cell biology 135 (6), 1633-1642, 1996	984	1996
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product P Crespo, KE Schuebel, AA Ostrom, JS Gutkind, XR Bustelo Nature 385 (6612), 169-172, 1997	981	1997
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ M Lopez-Ilasaca, P Crespo, PG Pellici, JS Gutkind, R Wetzker Science 275 (5298), 394-397, 1997	885	1997
Augmented Wnt signaling in a mammalian model of accelerated aging H Liu, MM Fergusson, RM Castilho, J Liu, L Cao, J Chen, D Malide, ... Science 317 (5839), 803-806, 2007	884	2007
Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers X Yu, B Munge, V Patel, G Jensen, A Bhirde, JD Gong, SN Kim, ... Journal of the American Chemical Society 128 (34), 11199-11205, 2006	803	2006
G₁₂-G₁₃–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension A Wirth, Z Benyó, M Lukasova, B Leutgeb, N Wettschureck, S Gorbey, ... Nature medicine 14 (1), 64-68, 2008	767	2008
Cbl-b regulates the CD28 dependence of T-cell activation YJ Chiang, HK Kole, K Brown, M Naramura, S Fukuhara, RJ Hu, IK Jang, ... Nature 403 (6766), 216-220, 2000	736	2000
Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer JF Rusling, CV Kumar, JS Gutkind, V Patel Analyst 135 (10), 2496-2511, 2010	656	2010
Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry X Feng, MS Degese, R Iglesias-Bartolome, JP Vaque, AA Molinolo, ... Cancer cell 25 (6), 831-845, 2014	615	2014

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