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Gavin Oudit
Gavin Oudit
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Angiotensin-converting enzyme 2 is an essential regulator of heart function
MA Crackower, R Sarao, GY Oudit, C Yagil, I Kozieradzki, SE Scanga, ...
Nature 417 (6891), 822-828, 2002
23342002
Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2
M Gheblawi, K Wang, A Viveiros, Q Nguyen, JC Zhong, AJ Turner, ...
Circulation research 126 (10), 1456-1474, 2020
22412020
Cells of the adult human heart
M Litviňuková, C Talavera-López, H Maatz, D Reichart, CL Worth, ...
Nature 588 (7838), 466-472, 2020
13822020
SARS‐coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
GY Oudit, Z Kassiri, C Jiang, PP Liu, SM Poutanen, JM Penninger, ...
European journal of clinical investigation 39 (7), 618-625, 2009
11312009
Role of the ACE2/angiotensin 1–7 axis of the renin–angiotensin system in heart failure
VB Patel, JC Zhong, MB Grant, GY Oudit
Circulation research 118 (8), 1313-1326, 2016
9702016
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
MA Crackower, GY Oudit, I Kozieradzki, R Sarao, H Sun, T Sasaki, ...
Cell 110 (6), 737-749, 2002
8092002
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
GY Oudit, H Sun, BG Kerfant, MA Crackower, JM Penninger, PH Backx
Journal of molecular and cellular cardiology 37 (2), 449-471, 2004
6412004
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
GY Oudit, H Sun, MG Trivieri, SE Koch, F Dawood, C Ackerley, ...
Nature medicine 9 (9), 1187-1194, 2003
5692003
Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction
JC Zhong, R Basu, D Guo, FL Chow, S Byrns, M Schuster, H Loibner, ...
Circulation 122 (7), 717-728, 2010
5322010
Dendritic cell–induced autoimmune heart failure requires cooperation between adaptive and innate immunity
U Eriksson, R Ricci, L Hunziker, MO Kurrer, GY Oudit, TH Watts, ...
Nature medicine 9 (12), 1484-1490, 2003
5222003
Multidisciplinary approach to novel therapies in cardio-oncology research (MANTICORE 101–Breast): a randomized trial for the prevention of trastuzumab-associated cardiotoxicity
E Pituskin, JR Mackey, S Koshman, D Jassal, M Pitz, MJ Haykowsky, ...
Journal of clinical oncology 35 (8), 870-877, 2017
4202017
Empagliflozin increases cardiac energy production in diabetes: novel translational insights into the heart failure benefits of SGLT2 inhibitors
S Verma, S Rawat, KL Ho, CS Wagg, L Zhang, H Teoh, JE Dyck, ...
JACC: Basic to Translational Science 3 (5), 575-587, 2018
4072018
Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters
TA Martino, GY Oudit, AM Herzenberg, N Tata, MM Koletar, GM Kabir, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008
3762008
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis
F Lovren, Y Pan, A Quan, H Teoh, G Wang, PC Shukla, KS Levitt, ...
American Journal of Physiology-Heart and Circulatory Physiology 295 (4 …, 2008
3752008
The role of ACE2 in cardiovascular physiology
GY Oudit, MA Crackower, PH Backx, JM Penninger
Trends in cardiovascular medicine 13 (3), 93-101, 2003
3752003
Human recombinant ACE2 reduces the progression of diabetic nephropathy
GY Oudit, GC Liu, JC Zhong, R Basu, FL Chow, J Zhou, H Loibner, ...
Diabetes 59 (2), 529-538, 2010
3622010
Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS
VB Patel, N Clarke, Z Wang, D Fan, N Parajuli, R Basu, B Putko, Z Kassiri, ...
Journal of molecular and cellular cardiology 66, 167-176, 2014
3602014
The renin-angiotensin system: going beyond the classical paradigms
RAS Santos, GY Oudit, T Verano-Braga, G Canta, UM Steckelings, ...
American Journal of Physiology-Heart and Circulatory Physiology 316 (5 …, 2019
3392019
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
DW Wong, GY Oudit, H Reich, Z Kassiri, J Zhou, QC Liu, PH Backx, ...
The American journal of pathology 171 (2), 438-451, 2007
3342007
Iron-overload cardiomyopathy: pathophysiology, diagnosis, and treatment
CJ Murphy, GY Oudit
Journal of cardiac failure 16 (11), 888-900, 2010
3322010
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