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Jacob Aaron Blum
Jacob Aaron Blum
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Neurotoxic reactive astrocytes induce cell death via saturated lipids
KA Guttenplan, MK Weigel, P Prakash, PR Wijewardhane, P Hasel, ...
Nature 599 (7883), 102-107, 2021
4672021
Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons
JA Blum, S Klemm, JL Shadrach, KA Guttenplan, L Nakayama, A Kathiria, ...
Nature neuroscience 24 (4), 572-583, 2021
1572021
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly (PR)
M Maor-Nof, Z Shipony, R Lopez-Gonzalez, L Nakayama, YJ Zhang, ...
Cell 184 (3), 689-708. e20, 2021
1412021
Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
S Lu, J Hu, OA Arogundade, A Goginashvili, S Vazquez-Sanchez, ...
Nature cell biology 24 (9), 1378-1393, 2022
942022
Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease
S Boeynaems, XR Ma, V Yeong, GM Ginell, JH Chen, JA Blum, ...
BioRxiv, 2023
232023
The Hybrid Incompatibility Genes Lhr and Hmr Are Required for Sister Chromatid Detachment During Anaphase but Not for Centromere Function
JA Blum, S Bonaccorsi, M Marzullo, V Palumbo, YM Yamashita, ...
Genetics 207 (4), 1457-1472, 2017
232017
Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro
T Patel, J Hammelman, S Aziz, S Jang, M Closser, TL Michaels, JA Blum, ...
Nature communications 13 (1), 5427, 2022
222022
Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2
G Kim, L Nakayama, JA Blum, T Akiyama, S Boeynaems, M Chakraborty, ...
Cell reports 41 (4), 2022
202022
A molecular atlas of adult C. elegans motor neurons reveals ancient diversity delineated by conserved transcription factor codes
JJ Smith, SR Taylor, JA Blum, W Feng, R Collings, AD Gitler, DM Miller, ...
Cell reports 43 (3), 2024
172024
Singling out motor neurons in the age of single-cell transcriptomics
JA Blum, AD Gitler
Trends in Genetics 38 (9), 904-919, 2022
162022
High potency zinc modulation of human P2X2 receptors and low potency zinc modulation of rat P2X2 receptors share a common molecular mechanism
S Punthambaker, JA Blum, RI Hume
Journal of Biological Chemistry 287 (26), 22099-22111, 2012
162012
Diffusion basis spectrum imaging predicts long-term clinical outcomes following surgery in cervical spondylotic myelopathy
JK Zhang, D Jayasekera, S Javeed, JK Greenberg, J Blum, CF Dibble, ...
The Spine Journal 23 (4), 504-512, 2023
112023
Human motor neurons are rare and can be transcriptomically divided into known subtypes
O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ...
BioRxiv, 2023.04. 05.535689, 2023
82023
Challenges of profiling motor neuron transcriptomes from human spinal cord
O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ...
Neuron 111 (23), 3739-3741, 2023
52023
Single-cell transcriptomic analysis of the adult mouse spinal cord
JA Blum, S Klemm, L Nakayama, A Kathiria, KA Guttenplan, PT Hoang, ...
Biorxiv, 2020.03. 16.992958, 2020
52020
A role for microglia in retinal development
K Guttenplan, J Blum, M Bennett
The Journal of Neuroscience 38 (43), 9126, 2018
52018
Transvection between nonallelic genomic positions in Drosophila
JA Blum, M Wells, Z Huxley-Reicher, JE Johnson, JR Bateman
G3: Genes, Genomes, Genetics 14 (2), jkad255, 2024
32024
AlphaFold’s Predictive Revolution in Precision Oncology
X Zhao, VB Yang, AK Menta, J Blum, A Wahida, V Subbiah
AI in Precision Oncology 1 (3), 160-167, 2024
12024
Association of dysautonomia with refractory ventricular tachyarrhythmia in patients requiring thoracoscopic surgical cardiac sympathetic denervation
A Gurau, D Perdomo, H Khan, K Melinosky, A Chudnovets, J Blum, ...
JTCVS Open, 2024
2024
Maryland's Global Budget Revenue Program and Equitable Access to Esophagectomy for Esophageal Cancer
VB Yang, HJ Rando, AK Menta, X Zhao, J Blum, R Battafarano, ...
Journal of Surgical Research 302, 403-410, 2024
2024
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Artikler 1–20