Discovery of 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in … P Jones, S Altamura, J Boueres, F Ferrigno, M Fonsi, C Giomini, ... Journal of medicinal chemistry 52 (22), 7170-7185, 2009 | 364 | 2009 |
Mismatch repair deficiency associated with overexpression of the MSH3 gene G Marra, I Iaccarino, T Lettieri, G Roscilli, P Delmastro, J Jiricny Proceedings of the National Academy of Sciences 95 (15), 8568-8573, 1998 | 265 | 1998 |
SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines G Salvatori, L Luberto, M Maffei, L Aurisicchio, G Roscilli, F Palombo, ... Journal of translational medicine 18 (1), 222, 2020 | 212 | 2020 |
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ A Noto, C De Vitis, ME Pisanu, G Roscilli, G Ricci, A Catizone, ... Oncogene 36 (32), 4573-4584, 2017 | 184 | 2017 |
Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells A Noto, S Raffa, C De Vitis, G Roscilli, D Malpicci, P Coluccia, A Di Napoli, ... Cell death & disease 4 (12), e947-e947, 2013 | 168 | 2013 |
Stringent Control of Gene Expression In Vivo by Using Novel Doxycycline-Dependent Trans-Activators S Lamartina, G Roscilli, CD Rinaudo, E Sporeno, L Silvi, W Hillen, ... Human gene therapy 13 (2), 199-210, 2002 | 122 | 2002 |
Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections S Terreri, EP Mortari, MR Vinci, C Russo, C Alteri, C Albano, F Colavita, ... Cell host & microbe 30 (3), 400-408. e4, 2022 | 107 | 2022 |
Construction of an rtTA2s-M2/tTSkid-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and … S Lamartina, L Silvi, G Roscilli, D Casimiro, AJ Simon, ME Davies, ... Molecular Therapy 7 (2), 271-280, 2003 | 103 | 2003 |
The promise of anti-ErbB3 monoclonals as new cancer therapeutics L Aurisicchio, E Marra, G Roscilli, R Mancini, G Ciliberto Oncotarget 3 (8), 744, 2012 | 91 | 2012 |
Epigenetic silencing of miR-145-5p contributes to brain metastasis S Donzelli, F Mori, T Bellissimo, A Sacconi, B Casini, T Frixa, G Roscilli, ... Oncotarget 6 (34), 35183, 2015 | 83 | 2015 |
Highly specific memory B cells generation after the 2nd dose of BNT162b2 vaccine compensate for the decline of serum antibodies and absence of mucosal IgA E Piano Mortari, C Russo, MR Vinci, S Terreri, A Fernandez Salinas, ... Cells 10 (10), 2541, 2021 | 82 | 2021 |
Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase D Pala, S Rivara, M Mor, FM Milazzo, G Roscilli, E Pavoni, G Giannini Glycobiology 26 (6), 640-654, 2016 | 78 | 2016 |
Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment R Mancini, E Giarnieri, C De Vitis, D Malanga, G Roscilli, A Noto, E Marra, ... PloS one 6 (7), e21320, 2011 | 78 | 2011 |
Helper‐dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy S Lamartina, M Cimino, G Roscilli, E Dammassa, D Lazzaro, R Rota, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007 | 72 | 2007 |
Lipofection of purified adeno-associated virus Rep68 protein: toward a chromosome-targeting nonviral particle S Lamartina, G Roscilli, D Rinaudo, P Delmastro, C Toniatti Journal of virology 72 (9), 7653-7658, 1998 | 72 | 1998 |
Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor F Kinose, G Roscilli, S Lamartina, KD Anderson, F Bonelli, SG Spence, ... Mol Vis 11, 366-373, 2005 | 69 | 2005 |
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models A Conforti, E Marra, F Palombo, G Roscilli, M Ravà, V Fumagalli, A Muzi, ... Molecular Therapy 30 (1), 311-326, 2022 | 66 | 2022 |
Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphoma A Gavazza, G Lubas, A Fridman, D Peruzzi, JA Impellizeri, L Luberto, ... Human gene therapy 24 (8), 728-738, 2013 | 64 | 2013 |
Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity G Roscilli, C De Vitis, FF Ferrara, A Noto, E Cherubini, A Ricci, S Mariotta, ... Journal of translational medicine 14, 1-14, 2016 | 63 | 2016 |
MicroRNA-128-3p-mediated depletion of Drosha promotes lung cancer cell migration T Frixa, A Sacconi, M Cioce, G Roscilli, FF Ferrara, L Aurisicchio, C Pulito, ... Carcinogenesis 39 (2), 293-304, 2018 | 44 | 2018 |