| The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization MCL Wu, FH Brennan, JPL Lynch, S Mantovani, S Phipps, RA Wetsel, ... Proceedings of the National Academy of Sciences 110 (23), 9439-9444, 2013 | 171 | 2013 |
| Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells J Simpson, Z Loh, MA Ullah, JP Lynch, RB Werder, N Collinson, V Zhang, ... American journal of respiratory and critical care medicine 201 (11), 1358-1371, 2020 | 118 | 2020 |
| Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics JP Lynch, L Goers, CF Lesser Trends in Pharmacological Sciences 43 (9), 772-786, 2022 | 101 | 2022 |
| Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity JP Lynch, RB Werder, J Simpson, Z Loh, V Zhang, A Haque, K Spann, ... Journal of Allergy and Clinical Immunology 138 (5), 1326-1337, 2016 | 98 | 2016 |
| Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice GE Kaiko, Z Loh, K Spann, JP Lynch, A Lalwani, Z Zheng, S Davidson, ... Journal of allergy and clinical immunology 131 (5), 1331-1339. e10, 2013 | 86 | 2013 |
| Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a–mediated T reg expansion JP Lynch, RB Werder, Z Loh, MAA Sikder, B Curren, V Zhang, MJ Rogers, ... Journal of Experimental Medicine 215 (2), 537-557, 2018 | 85 | 2018 |
| Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity RB Werder, V Zhang, JP Lynch, N Snape, JW Upham, K Spann, S Phipps Journal of Allergy and Clinical Immunology 141 (5), 1607-1619. e9, 2018 | 77 | 2018 |
| The plasmacytoid dendritic cell: at the cross-roads in asthma JP Lynch, SB Mazzone, MJ Rogers, JJ Arikkatt, Z Loh, AL Pritchard, ... European Respiratory Journal 43 (1), 264-275, 2013 | 73 | 2013 |
| Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection MAA Sikder, RB Rashid, T Ahmed, I Sebina, DR Howard, MA Ullah, ... Immunity 56 (5), 1098-1114. e10, 2023 | 64 | 2023 |
| PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production RB Werder, JP Lynch, JC Simpson, V Zhang, NH Hodge, M Poh, ... Science translational medicine 10 (440), eaao0052, 2018 | 62 | 2018 |
| Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut JP Lynch, C González-Prieto, AZ Reeves, S Bae, U Powale, NP Godbole, ... Cell Host & Microbe 31 (4), 634-649. e8, 2023 | 56 | 2023 |
| Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma RB Werder, MA Ullah, MM Rahman, J Simpson, JP Lynch, N Collinson, ... American Journal of Respiratory and Critical Care Medicine 205 (3), 300-312, 2022 | 52 | 2022 |
| The influence of the microbiome on early-life severe viral lower respiratory infections and asthma—food for thought? JP Lynch, MAA Sikder, BF Curren, RB Werder, J Simpson, PÓ Cuív, ... Frontiers in immunology 8, 156, 2017 | 48 | 2017 |
| Regulatory T cells prevent inducible BALT formation by dampening neutrophilic inflammation SY Foo, V Zhang, A Lalwani, JP Lynch, A Zhuang, CE Lam, PS Foster, ... The Journal of Immunology 194 (9), 4567-4576, 2015 | 45 | 2015 |
| HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling Z Loh, J Simpson, A Ullah, V Zhang, WJ Gan, JP Lynch, RB Werder, ... PLoS pathogens 16 (7), e1008651, 2020 | 42 | 2020 |
| Immunomodulation of Airway Epithelium Cell Activation by Mesenchymal Stromal Cells Ameliorates House Dust Mite–Induced Airway Inflammation in Mice KM Duong, J Arikkatt, MA Ullah, JP Lynch, V Zhang, K Atkinson, PD Sly, ... American journal of respiratory cell and molecular biology 53 (5), 615-624, 2015 | 35 | 2015 |
| IRF-3, IRF-7, and IPS-1 promote host defense against acute human metapneumovirus infection in neonatal mice KM Spann, Z Loh, JP Lynch, A Ullah, V Zhang, E Baturcam, RB Werder, ... The American journal of pathology 184 (6), 1795-1806, 2014 | 28 | 2014 |
| Th2/Th17 reciprocal regulation: twists and turns in the complexity of asthma phenotypes JP Lynch, MA Ferreira, S Phipps Annals of translational medicine 4 (Suppl 1), S59, 2016 | 21 | 2016 |
| Long-lived regulatory T cells generated during severe bronchiolitis in infancy influence later progression to asthma JP Lynch, RB Werder, BF Curren, MAA Sikder, A Ullah, I Sebina, ... Mucosal Immunology 13 (4), 652-664, 2020 | 19 | 2020 |
| Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16 Y Xi, NM Troy, D Anderson, OM Pena, JP Lynch, S Phipps, A Bosco, ... Frontiers in Immunology 8, 1351, 2017 | 18 | 2017 |