Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ... Molecular cell 57 (5), 860-872, 2015 | 455 | 2015 |
Deregulated MYC expression induces dependence upon AMPK-related kinase 5 L Liu, J Ulbrich, J Müller, T Wüstefeld, L Aeberhard, TR Kress, ... Nature 483 (7391), 608-612, 2012 | 323 | 2012 |
Developmental regulation of mitochondrial apoptosis by c-Myc governs age-and tissue-specific sensitivity to cancer therapeutics KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer, ... Cancer cell 31 (1), 142-156, 2017 | 257 | 2017 |
Glutamine anabolism plays a critical role in pancreatic cancer by coupling carbon and nitrogen metabolism AJ Bott, J Shen, C Tonelli, L Zhan, N Sivaram, YP Jiang, X Yu, V Bhatt, ... Cell reports 29 (5), 1287-1298. e6, 2019 | 155 | 2019 |
Repression of the type I interferon pathway underlies MYC-and KRAS-dependent evasion of NK and B cells in pancreatic ductal adenocarcinoma N Muthalagu, T Monteverde, X Raffo-Iraolagoitia, R Wiesheu, D Whyte, ... Cancer discovery 10 (6), 872-887, 2020 | 147 | 2020 |
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance AS Farrell, MM Joly, BL Allen-Petersen, PJ Worth, C Lanciault, D Sauer, ... Nature communications 8 (1), 1728, 2017 | 112 | 2017 |
Evidence of cancer‐promoting roles for AMPK and related kinases T Monteverde, N Muthalagu, J Port, DJ Murphy The FEBS journal 282 (24), 4658-4671, 2015 | 101 | 2015 |
BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues N Muthalagu, MR Junttila, KE Wiese, E Wolf, J Morton, B Bauer, GI Evan, ... Cell reports 8 (5), 1347-1353, 2014 | 89 | 2014 |
Colorectal tumors require NUAK1 for protection from oxidative stress J Port, N Muthalagu, M Raja, F Ceteci, T Monteverde, B Kruspig, A Hedley, ... Cancer Discovery 8 (5), 632-647, 2018 | 81 | 2018 |
Repression of the type I interferon pathway underlies MYC-and KRAS-dependent evasion of NK and B cells in pancreatic ductal adenocarcinoma. Cancer Discov. 2020; 10: 872–887 … N Muthalagu, T Monteverde, X Raffo-Iraolagoitia, R Wiesheu, D Whyte, ... CD-19-0620.[Europe PMC free article][Abstract][CrossRef][Academic Search], 0 | 18 | |
NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β‐dependent regulation of PLK4 D Whyte, G Skalka, P Walsh, A Wilczynska, NR Paul, C Mitchell, C Nixon, ... Molecular Oncology 17 (7), 1212-1227, 2023 | 8 | 2023 |
Is oxidative stress MYC’s Achilles heel? N Muthalagu, DJ Murphy Cell Death and Differentiation 25 (7), 1189, 2018 | 5 | 2018 |
BIM's up first DJ Murphy, N Muthalagu Molecular & Cellular Oncology 2 (2), e975083, 2015 | 1 | 2015 |
RNA-SEQ analysis of human U2OS cells with/without depletion of NUAK1 by shRNA N Muthalagu, G Kalna, A Hedley, D Murphy ArrayExpress, 2018 | | 2018 |
The AMPK-related kinase NUAK1 is a target for treatment of colorectal cancer J Port, N Muthalagu, M Raja, T Monteverde, M Mezna, F Ceteci, G Murray, ... European Journal of Cancer 61, S68, 2016 | | 2016 |
Stabilization of Wild-Type MLL Displaces Oncogenic MLL Fusion Proteins KA Sarosiek, C Fraser, N Muthalagu, PD Bhola, W Chang, SK McBrayer | | |