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Nicholas C Spies
Nicholas C Spies
University of Utah/ARUP Laboratories
Verifisert e-postadresse på aruplab.com
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DGIdb 3.0: a redesign and expansion of the drug–gene interaction database
KC Cotto, AH Wagner, YY Feng, S Kiwala, AC Coffman, G Spies, ...
Nucleic acids research 46 (D1), D1068-D1073, 2018
8422018
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer
M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ...
Nature genetics 49 (2), 170-174, 2017
6022017
DGIdb: mining the druggable genome
M Griffith, OL Griffith, AC Coffman, JV Weible, JF McMichael, NC Spies, ...
Nature methods 10 (12), 1209-1210, 2013
5392013
DGIdb 2.0: mining clinically relevant drug–gene interactions
AH Wagner, AC Coffman, BJ Ainscough, NC Spies, ZL Skidmore, ...
Nucleic acids research 44 (D1), D1036-D1044, 2016
4102016
NeoPalAna: neoadjuvant palbociclib, a cyclin-dependent kinase 4/6 inhibitor, and anastrozole for clinical stage 2 or 3 estrogen receptor–positive breast cancer
CX Ma, F Gao, J Luo, DW Northfelt, M Goetz, A Forero, J Hoog, ...
Clinical Cancer Research 23 (15), 4055-4065, 2017
3452017
Neoadjuvant and adjuvant pembrolizumab in resectable locally advanced, human papillomavirus–unrelated head and neck cancer: a multicenter, phase II trial
R Uppaluri, KM Campbell, AM Egloff, P Zolkind, ZL Skidmore, ...
Clinical Cancer Research 26 (19), 5140-5152, 2020
2832020
Informatics for RNA sequencing: a web resource for analysis on the cloud
M Griffith, JR Walker, NC Spies, BJ Ainscough, OL Griffith
PLoS computational biology 11 (8), e1004393, 2015
1622015
Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer
AH Wagner, S Devarakonda, ZL Skidmore, K Krysiak, A Ramu, L Trani, ...
Nature communications 9 (1), 3787, 2018
1432018
The prognostic effects of somatic mutations in ER-positive breast cancer
OL Griffith, NC Spies, M Anurag, M Griffith, J Luo, D Tu, B Yeo, J Kunisaki, ...
Nature communications 9 (1), 3476, 2018
1412018
A phase I trial of BKM120 (Buparlisib) in combination with fulvestrant in postmenopausal women with estrogen receptor–positive metastatic breast cancer
CX Ma, J Luo, M Naughton, F Ademuyiwa, R Suresh, M Griffith, OL Griffith, ...
Clinical cancer research 22 (7), 1583-1591, 2016
1012016
Standard operating procedure for somatic variant refinement of sequencing data with paired tumor and normal samples
EK Barnell, P Ronning, KM Campbell, K Krysiak, BJ Ainscough, LM Sheta, ...
Genetics in Medicine 21 (4), 972-981, 2019
922019
Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia
M Griffith, OL Griffith, K Krysiak, ZL Skidmore, MJ Christopher, JM Klco, ...
Experimental hematology 44 (7), 603-613, 2016
562016
Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element
W Leung, CD Shaffer, EJ Chen, TJ Quisenberry, K Ko, JM Braverman, ...
G3: Genes, Genomes, Genetics 7 (8), 2439-2460, 2017
272017
Organizational preparedness for the use of large language models in pathology informatics
SN Hart, NG Hoffman, P Gershkovich, C Christenson, DS McClintock, ...
Journal of Pathology Informatics 14, 100338, 2023
242023
Machine-learning algorithm incorporating capacitated sperm intracellular pH predicts conventional in vitro fertilization success in normospermic patients
SJ Gunderson, LCP Molina, N Spies, PA Balestrini, MG Buffone, ...
Fertility and sterility 115 (4), 930-939, 2021
242021
Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival
EN Kotnik, MM Mullen, NC Spies, T Li, M Inkman, J Zhang, ...
Communications biology 6 (1), 688, 2023
202023
CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase
K Krysiak, AM Danos, J Saliba, JF McMichael, AC Coffman, S Kiwala, ...
Nucleic acids research 51 (D1), D1230-D1241, 2023
192023
Standard operating procedure for curation and clinical interpretation of variants in cancer
AM Danos, K Krysiak, EK Barnell, AC Coffman, JF McMichael, S Kiwala, ...
Genome medicine 11, 1-12, 2019
182019
Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma
EK Barnell, ZL Skidmore, KF Newcomer, M Chavez, KM Campbell, ...
Blood Advances 7 (2), 236-245, 2023
122023
Automating the detection of IV fluid contamination using unsupervised machine learning
NC Spies, Z Hubler, V Azimi, R Zhang, R Jackups Jr, AM Gronowski, ...
Clinical chemistry 70 (2), 444-452, 2024
102024
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