| Cyclohexylcarbamic acid 3 ‘-or 4 ‘-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure− activity relationships, and … M Mor, S Rivara, A Lodola, PV Plazzi, G Tarzia, A Duranti, A Tontini, ... Journal of medicinal chemistry 47 (21), 4998-5008, 2004 | 340 | 2004 |
| Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation C Solorzano, C Zhu, N Battista, G Astarita, A Lodola, S Rivara, M Mor, ... Proceedings of the National Academy of Sciences 106 (49), 20966-20971, 2009 | 271 | 2009 |
| A catalytically silent FAAH-1 variant drives anandamide transport in neurons J Fu, G Bottegoni, O Sasso, R Bertorelli, W Rocchia, M Masetti, A Guijarro, ... Nature neuroscience 15 (1), 64-69, 2012 | 224 | 2012 |
| 5-Benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity C Carmi, A Cavazzoni, V Zuliani, A Lodola, F Bordi, PV Plazzi, RR Alfieri, ... Bioorganic & medicinal chemistry letters 16 (15), 4021-4025, 2006 | 136 | 2006 |
| Discovery of potent and reversible monoacylglycerol lipase inhibitors AR King, EY Dotsey, A Lodola, KM Jung, A Ghomian, Y Qiu, J Fu, M Mor, ... Chemistry & biology 16 (10), 1045-1052, 2009 | 129 | 2009 |
| Mechanism of inhibition of SARS-CoV-2 M pro by N3 peptidyl Michael acceptor explained by QM/MM simulations and design of new derivatives with tunable chemical reactivity K Arafet, N Serrano-Aparicio, A Lodola, AJ Mulholland, FV González, ... Chemical Science 12 (4), 1433-1444, 2021 | 123 | 2021 |
| Predicting the reactivity of nitrile-carrying compounds with cysteine: a combined computational and experimental study A Berteotti, F Vacondio, A Lodola, M Bassi, C Silva, M Mor, A Cavalli ACS medicinal chemistry letters 5 (5), 501-505, 2014 | 106 | 2014 |
| N-(Substituted-anilinoethyl)amides: Design, Synthesis, and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands S Rivara, A Lodola, M Mor, A Bedini, G Spadoni, V Lucini, M Pannacci, ... Journal of medicinal chemistry 50 (26), 6618-6626, 2007 | 105 | 2007 |
| A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone‐based enzyme inhibitors AR King, A Lodola, C Carmi, J Fu, M Mor, D Piomelli British journal of pharmacology 157 (6), 974-983, 2009 | 100 | 2009 |
| Targeting Eph/ephrin system in cancer therapy A Lodola, C Giorgio, M Incerti, I Zanotti, M Tognolini European journal of medicinal chemistry 142, 152-162, 2017 | 94 | 2017 |
| Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation C Giorgio, I Hassan Mohamed, L Flammini, E Barocelli, M Incerti, ... PloS one 6 (3), e18128, 2011 | 94 | 2011 |
| Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase A Lodola, M Mor, J Zurek, G Tarzia, D Piomelli, JN Harvey, AJ Mulholland Biophysical journal 92 (2), L20-L22, 2007 | 92 | 2007 |
| Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines A Cavazzoni, RR Alfieri, C Carmi, V Zuliani, M Galetti, C Fumarola, ... Molecular Cancer Therapeutics 7 (2), 361-370, 2008 | 90 | 2008 |
| Irreversible inhibition of epidermal growth factor receptor activity by 3-aminopropanamides C Carmi, E Galvani, F Vacondio, S Rivara, A Lodola, S Russo, S Aiello, ... Journal of medicinal chemistry 55 (5), 2251-2264, 2012 | 85 | 2012 |
| L718Q mutant EGFR escapes covalent inhibition by stabilizing a non-reactive conformation of the lung cancer drug osimertinib D Callegari, KE Ranaghan, CJ Woods, R Minari, M Tiseo, M Mor, ... Chemical Science 9 (10), 2740-2749, 2018 | 84 | 2018 |
| Novel irreversible epidermal growth factor receptor inhibitors by chemical modulation of the cysteine-trap portion C Carmi, A Cavazzoni, S Vezzosi, F Bordi, F Vacondio, C Silva, S Rivara, ... Journal of medicinal chemistry 53 (5), 2038-2050, 2010 | 81 | 2010 |
| Synthesis and quantitative structure− activity relationship of fatty acid amide hydrolase inhibitors: Modulation at the N-portion of biphenyl-3-yl alkylcarbamates M Mor, A Lodola, S Rivara, F Vacondio, A Duranti, A Tontini, S Sanchini, ... Journal of medicinal chemistry 51 (12), 3487-3498, 2008 | 78 | 2008 |
| A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations A Lodola, D Branduardi, M De Vivo, L Capoferri, M Mor, D Piomelli, ... PLoS One 7 (2), e32397, 2012 | 76 | 2012 |
| Synthesis and Structure−Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors C Solorzano, F Antonietti, A Duranti, A Tontini, S Rivara, A Lodola, ... Journal of medicinal chemistry 53 (15), 5770-5781, 2010 | 76 | 2010 |
| Synthesis and structure–activity relationships of FAAH inhibitors: cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring G Tarzia, A Duranti, G Gatti, G Piersanti, A Tontini, S Rivara, A Lodola, ... ChemMedChem: Chemistry Enabling Drug Discovery 1 (1), 130-139, 2006 | 76 | 2006 |
Marco MorUniversity of Parma, Università degli Studi di ParmaVerifisert e-postadresse på unipr.it
