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Aymen Idris
Aymen Idris
Pharmacology Researcher, University of Sheffield.
Verifisert e-postadresse på sheffield.ac.uk - Startside
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Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
AI Idris, RJ van't Hof, IR Greig, SA Ridge, D Baker, RA Ross, SH Ralston
Nature medicine 11 (7), 774-779, 2005
4632005
Aminobisphosphonates cause osteoblast apoptosis and inhibit bone nodule formation in vitro
AI Idris, J Rojas, IR Greig, RJ van’t Hof, SH Ralston
Calcified tissue international 82, 191-201, 2008
2682008
Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells
AI Idris, A Sophocleous, E Landao-Bassonga, M Canals, G Milligan, ...
Cell Metabolism 10 (2), 139-147, 2009
2022009
Regulation of bone mass, osteoclast function, and ovariectomy-induced bone loss by the type 2 cannabinoid receptor
AI Idris, A Sophocleous, E Landao-Bassonga, RJ Van't Hof, SH Ralston
Endocrinology 149 (11), 5619-5626, 2008
1762008
The TRPV1 ion channel antagonist capsazepine inhibits osteoclast and osteoblast differentiation in vitro and ovariectomy induced bone loss in vivo
AI Idris, E Landao-Bassonga, SH Ralston
Bone 46 (4), 1089-1099, 2010
1342010
The type 2 cannabinoid receptor regulates bone mass and ovariectomy-induced bone loss by affecting osteoblast differentiation and bone formation
A Sophocleous, E Landao-Bassonga, RJ van ‘t Hof, AI Idris, SH Ralston
Endocrinology 152 (6), 2141-2149, 2011
1182011
Pharmacologic inhibitors of IκB kinase suppress growth and migration of mammary carcinosarcoma cells in vitro and prevent osteolytic bone metastasis in vivo
AI Idris, H Libouban, H Nyangoga, E Landao-Bassonga, D Chappard, ...
Molecular cancer therapeutics 8 (8), 2339-2347, 2009
1142009
β2-Adrenoreceptor ligands regulate osteoclast differentiation in vitro by direct and indirect mechanisms
SJ Aitken, E Landao-Bassonga, SH Ralston, AI Idris
Archives of biochemistry and biophysics 482 (1-2), 96-103, 2009
1122009
Rodent models of osteoporosis
A Sophocleous, AI Idris
BoneKEy reports 3, 614, 2014
1052014
Role of cannabinoids in the regulation of bone remodeling
AI Idris, SH Ralston
Frontiers in endocrinology 3, 136, 2012
1002012
Ovariectomy/orchidectomy in rodents
AI Idris
Bone research protocols, 545-551, 2012
1002012
Cannabinoids and bone: friend or foe?
AI Idris, SH Ralston
Calcified tissue international 87 (4), 285-297, 2010
902010
A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo
A Hughes, MJ Rogers, AI Idris, JC Crockett
Calcified tissue international 81, 403-413, 2007
842007
Small molecule inhibitors of IκB kinase signaling inhibit osteoclast formation in vitro and prevent ovariectomy‐induced bone loss in vivo
AI Idris, M Krishnan, P Simic, E Landao‐Bassonga, P Mollat, S Vukicevic, ...
The FASEB Journal 24 (11), 4545-4555, 2010
612010
Hydrogen sulphide‐releasing diclofenac derivatives inhibit breast cancer‐induced osteoclastogenesis in vitro and prevent osteolysis ex vivo
J Frantzias, JG Logan, P Mollat, A Sparatore, P Del Soldato, SH Ralston, ...
British journal of pharmacology 165 (6), 1914-1925, 2012
562012
Combined deficiency of the Cnr1 and Cnr2 receptors protects against age‐related bone loss by osteoclast inhibition
A Sophocleous, S Marino, D Kabir, SH Ralston, AI Idris
Aging Cell 16 (5), 1051-1061, 2017
482017
Cannabinoid receptors as target for treatment of osteoporosis: a tale of two therapies
A I Idris
Current neuropharmacology 8 (3), 243-253, 2010
462010
Emerging therapeutic targets in cancer induced bone disease: a focus on the peripheral type 2 cannabinoid receptor
S Marino, AI Idris
Pharmacological Research 119, 391-403, 2017
422017
Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice
S Marino, D de Ridder, RT Bishop, N Renema, M Ponzetti, ...
EBioMedicine 44, 452-466, 2019
362019
Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast cancer-induced osteolysis
A Sophocleous, S Marino, JG Logan, P Mollat, SH Ralston, AI Idris
Journal of Biological Chemistry 290 (36), 22049-22060, 2015
362015
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Artikler 1–20