Immunomodulation by ionizing radiation—impact for design of radio‐immunotherapies and for treatment of inflammatory diseases B Frey, M Rückert, L Deloch, PF Rühle, A Derer, R Fietkau, US Gaipl Immunological reviews 280 (1), 231-248, 2017 | 192 | 2017 |
Modern radiotherapy concepts and the impact of radiation on immune activation L Deloch, A Derer, J Hartmann, B Frey, R Fietkau, US Gaipl Frontiers in oncology 6, 141, 2016 | 175 | 2016 |
Immune modulatory effects of radiotherapy as basis for well-reasoned radioimmunotherapies M Rückert, L Deloch, R Fietkau, B Frey, M Hecht, US Gaipl Strahlentherapie und Onkologie 194 (6), 509-519, 2018 | 118 | 2018 |
Radio-immunotherapy-induced immunogenic cancer cells as basis for induction of systemic anti-tumor immune responses–pre-clinical evidence and ongoing clinical applications A Derer, L Deloch, Y Rubner, R Fietkau, B Frey, US Gaipl Frontiers in immunology 6, 505, 2015 | 114 | 2015 |
Clinically relevant radiation exposure differentially impacts forms of cell death in human cells of the innate and adaptive immune system SE Falcke, PF Rühle, L Deloch, R Fietkau, B Frey, US Gaipl International journal of molecular sciences 19 (11), 3574, 2018 | 102 | 2018 |
Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling A Distler, L Deloch, J Huang, C Dees, NY Lin, K Palumbo-Zerr, C Beyer, ... Annals of the rheumatic diseases 72 (9), 1575-1580, 2013 | 96 | 2013 |
Norm-and hypo-fractionated radiotherapy is capable of activating human dendritic cells L Kulzer, Y Rubner, L Deloch, A Allgäuer, B Frey, R Fietkau, J Dörrie, ... Journal of immunotoxicology 11 (4), 328-336, 2014 | 83 | 2014 |
Modulation of the peripheral immune system after low-dose radon spa therapy: Detailed longitudinal immune monitoring of patients within the RAD-ON01 study PF Rühle, R Wunderlich, L Deloch, C Fournier, A Maier, G Klein, ... Autoimmunity 50 (2), 133-140, 2017 | 68 | 2017 |
The influence of radiation on bone and bone cells—differential effects on osteoclasts and osteoblasts AJ Donaubauer, L Deloch, I Becker, R Fietkau, B Frey, US Gaipl International journal of molecular sciences 21 (17), 6377, 2020 | 67 | 2020 |
Low-dose radiotherapy ameliorates advanced arthritis in hTNF-α tg mice by particularly positively impacting on bone metabolism L Deloch, A Derer, AJ Hueber, M Herrmann, GA Schett, J Wölfelschneider, ... Frontiers in immunology 9, 1834, 2018 | 51 | 2018 |
Low‐dose irradiation differentially impacts macrophage phenotype in dependence of fibroblast‐like synoviocytes and radiation dose L Deloch, J Fuchs, M Rückert, R Fietkau, B Frey, US Gaipl Journal of immunology research 2019 (1), 3161750, 2019 | 44 | 2019 |
Deep learning for automatic head and neck lymph node level delineation provides expert-level accuracy T Weissmann, Y Huang, S Fischer, J Roesch, S Mansoorian, ... Frontiers in Oncology 13, 1115258, 2023 | 35 | 2023 |
Interconnection between DNA damage, senescence, inflammation, and cancer R Wunderlich, PF Ruehle, L Deloch, K Unger, J Hess, H Zitzelsberger, ... Front Biosci 22, 348-369, 2017 | 33 | 2017 |
Combinations of radiotherapy with vaccination and immune checkpoint inhibition differently affect primary and abscopal tumor growth and the tumor microenvironment M Rückert, L Deloch, B Frey, E Schlücker, R Fietkau, US Gaipl Cancers 13 (4), 714, 2021 | 32 | 2021 |
Low-dose radiotherapy has no harmful effects on key cells of healthy non-inflamed joints L Deloch, M Rückert, R Fietkau, B Frey, US Gaipl International Journal of Molecular Sciences 19 (10), 3197, 2018 | 30 | 2018 |
Low-dose radiotherapy leads to a systemic anti-inflammatory shift in the pre-clinical K/BxN serum transfer model and reduces osteoarthritic pain in patients T Weissmann, M Rückert, JG Zhou, M Seeling, S Lettmaier, ... Frontiers in Immunology 12, 777792, 2022 | 22 | 2022 |
Tumor cell-based vaccine generated with high hydrostatic pressure synergizes with radiotherapy by generating a favorable anti-tumor immune microenvironment C Seitz, M Rückert, L Deloch, EM Weiss, S Utz, M Izydor, N Ebel, ... Frontiers in Oncology 9, 805, 2019 | 20 | 2019 |
Hypofractionated radiotherapy upregulates several immune checkpoint molecules in head and neck squamous cell carcinoma cells independently of the HPV status while ICOS-L is … S Wimmer, L Deloch, M Hader, A Derer, F Grottker, T Weissmann, ... International Journal of Molecular Sciences 22 (17), 9114, 2021 | 18 | 2021 |
Tumor-specific radiosensitizing effect of the ATM inhibitor AZD0156 in melanoma cells with low toxicity to healthy fibroblasts J Scheper, LS Hildebrand, EM Faulhaber, L Deloch, US Gaipl, J Symank, ... Strahlentherapie und Onkologie 199 (12), 1128-1139, 2023 | 15 | 2023 |
Ionizing radiation reduces the capacity of activated macrophages to induce T-cell proliferation, but does not trigger dendritic cell-mediated non-targeted effects R Wunderlich, PF Rühle, L Deloch, F Rödel, R Fietkau, US Gaipl, B Frey International journal of radiation biology 95 (1), 33-43, 2019 | 14 | 2019 |