| Conformational transitions and allosteric modulation in a heteromeric glycine receptor E Gibbs, E Klemm, D Seiferth, A Kumar, SL Ilca, PC Biggin, S Chakrapani Nature communications 14 (1), 1363, 2023 | 24 | 2023 |
| Coarse graining of biochemical systems described by discrete stochastic dynamics D Seiferth, P Sollich, S Klumpp Physical Review E 102 (6), 062149, 2020 | 19 | 2020 |
| Atomistic mechanisms of human TRPA1 activation by electrophile irritants through molecular dynamics simulation and mutual information analysis M Habgood, D Seiferth, AM Zaki, I Alibay, PC Biggin Scientific Reports 12 (1), 4929, 2022 | 17 | 2022 |
| Learning transmission dynamics modelling of COVID-19 using comomodels SA van der Vegt, L Dai, I Bouros, HJ Farm, R Creswell, O Dimdore-Miles, ... Mathematical Biosciences 349, 108824, 2022 | 12 | 2022 |
| When is a hydrophobic gate not a hydrophobic gate? D Seiferth, PC Biggin, SJ Tucker Journal of General Physiology 154 (11), e202213210, 2022 | 5 | 2022 |
| Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment N Bharambe, Z Li, D Seiferth, AM Balakrishna, PC Biggin, S Basak Nature communications 15 (1), 2967, 2024 | 4 | 2024 |
| Exploring the influence of pore shape on conductance and permeation D Seiferth, PC Biggin Biophysical Journal 123 (18), 3107-3119, 2024 | 2 | 2024 |
| Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts D Seiferth, SJ Tucker, PC Biggin Physical Chemistry Chemical Physics 25 (26), 17596-17608, 2023 | 2 | 2023 |
| BPS2025-Mechanisms underlying modulation of human alpha3 glycine receptors by zinc and protons KJ Kindig, E Gibbs, D Seiferth, PC Biggin, S Chakrapani Biophysical Journal 124 (3), 283a, 2025 | | 2025 |
| BPS2025-Structural studies of heteromeric glycine receptor activation by orthosteric and allosteric agonists E Gibbs, S Chakrapani, E Klemm, PC Biggin, D Seiferth, B Feddersen Biophysical Journal 124 (3), 374a, 2025 | | 2025 |
| Mechanisms underlying modulation of human GlyRα3 by Zn2+ and pH K Kindig, E Gibbs, D Seiferth, PC Biggin, S Chakrapani Science Advances 10 (51), eadr5920, 2024 | | 2024 |
| Structural Dynamics of Heteromeric Glycine Receptor Complex E Gibbs, E Klemm, D Seiferth, A Kumar, SL Ilca, PC Biggin, S Chakrapani Microscopy and Microanalysis 30 (Supplement_1), ozae044. 357, 2024 | | 2024 |
| Conformational Transitions and Allosteric Modulation in a Heteromeric Glycine Receptor E Gibbs, E Klemm, D Seiferth, A Kumar, SL Ilca, PC Biggin, S Chakrapani Microscopy and Microanalysis 30 (Supplement_1), ozae044. 366, 2024 | | 2024 |
| Physiological and pharmacological modulation of alpha3 glycine receptors KJ Kindig, E Gibbs, S David, PC Biggin, S Chakrapani Biophysical Journal 123 (3), 396a, 2024 | | 2024 |
| Cryo-EM structures of nanodisc reconstituted ligand-gated ion channel GLIC in various conformations reveal state-dependent protein-lipid interactions and gating mechanism N Bharambe, Z Li, D Seiferth, AM Balakrishna, PC Biggin, S Basak Biophysical Journal 123 (3), 182a-183a, 2024 | | 2024 |
| Structural characterization of a full-length heteromeric glycine receptor in multiple functional states E Gibbs, E Krueger, A Kumar, S David, S Ilca, PC Biggin, S Chakrapani Biophysical Journal 122 (3), 249a, 2023 | | 2023 |
| Correction: Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts D Seiferth, SJ Tucker, PC Biggin Physical Chemistry Chemical Physics 25 (29), 20145-20145, 2023 | | 2023 |
Philip C. BigginProfessor of Computational Biochemistry, University of OxfordVerifisert e-postadresse på bioch.ox.ac.uk