A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin XX Yang, X Xu, MF Wang, HZ Xu, XC Peng, N Han, TT Yu, LG Li, QR Li, ... Journal of nanobiotechnology 20 (1), 230, 2022 | 53 | 2022 |
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer SJ Yuan, YH Xu, C Wang, HC An, HZ Xu, K Li, N Komatsu, L Zhao, ... Journal of Nanobiotechnology 17, 1-25, 2019 | 53 | 2019 |
Targeted photodynamic therapy of glioblastoma mediated by platelets with photo-controlled release property HZ Xu, TF Li, Y Ma, K Li, Q Zhang, YH Xu, YC Zhang, L Zhao, X Chen Biomaterials 290, 121833, 2022 | 44 | 2022 |
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy N Han, ZY Yang, ZX Xie, HZ Xu, TT Yu, QR Li, LG Li, XC Peng, XX Yang, ... Phytomedicine 112, 154682, 2023 | 43 | 2023 |
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancer through inhibiting GPX4 and enhancing ROS N Han, LG Li, XC Peng, QL Ma, ZY Yang, XY Wang, J Li, QR Li, TT Yu, ... European Journal of Pharmacology 919, 174797, 2022 | 43 | 2022 |
Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells HZ Xu, TF Li, C Wang, Y Ma, Y Liu, MY Zheng, ZJY Liu, JB Chen, K Li, ... Journal of Nanobiotechnology 19, 1-24, 2021 | 42 | 2021 |
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage LG Li, XC Peng, TT Yu, HZ Xu, N Han, XX Yang, QR Li, J Hu, B Liu, ... Frontiers in Pharmacology 13, 949835, 2022 | 38 | 2022 |
Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery QR Li, HZ Xu, RC Xiao, Y Liu, JM Tang, J Li, TT Yu, B Liu, LG Li, MF Wang, ... Drug Delivery 29 (1), 937-949, 2022 | 37 | 2022 |
Efficient delivery of chlorin e6 by polyglycerol-coated iron oxide nanoparticles with conjugated doxorubicin for enhanced photodynamic therapy of melanoma TF Li, HZ Xu, YH Xu, TT Yu, JM Tang, K Li, C Wang, XC Peng, QR Li, ... Molecular Pharmaceutics 18 (9), 3601-3615, 2021 | 35 | 2021 |
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes Z Chen, SJ Yuan, K Li, Q Zhang, TF Li, HC An, HZ Xu, Y Yue, M Han, ... Journal of Controlled Release 320, 469-483, 2020 | 28 | 2020 |
Surface-engineered carbon nanohorns as a theranostic nanodevice for photoacoustic imaging and effective radiochemotherapy of cancer D Li, Y Zhang, J Xu, F Yoshino, H Xu, X Chen, L Zhao Carbon 180, 185-196, 2021 | 27 | 2021 |
A dihydroartemisinin‐loaded nanoreactor motivates anti‐cancer immunotherapy by synergy‐induced ferroptosis to activate Cgas/STING for reprogramming of macrophage LG Li, XX Yang, HZ Xu, TT Yu, QR Li, J Hu, XC Peng, N Han, X Xu, ... Advanced Healthcare Materials 12 (28), 2301561, 2023 | 24 | 2023 |
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer TT Yu, XC Peng, MF Wang, N Han, HZ Xu, QR Li, LG Li, X Xu, QL Ma, ... Journal of Cancer Research and Clinical Oncology, 1-13, 2022 | 23 | 2022 |
Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells QL Ma, MO Shen, N Han, HZ Xu, XC Peng, QR Li, TT Yu, LG Li, X Xu, ... Photodiagnosis and Photodynamic Therapy 37, 102645, 2022 | 22 | 2022 |
Tumor Eradication by Boron Neutron Capture Therapy with 10B‐enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(Glycerol) Y Zhang, HG Kang, H Xu, H Luo, M Suzuki, Q Lan, X Chen, N Komatsu, ... Advanced Materials 35 (35), 2301479, 2023 | 21 | 2023 |
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates Z Chen, C Wang, TF Li, K Li, Y Yue, X Liu, HZ Xu, Y Wen, Q Zhang, M Han, ... Nanomedicine 14 (3), 335-351, 2019 | 18 | 2019 |
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin SJ Yuan, C Wang, HZ Xu, Y Liu, MY Zheng, K Li, SK Sun, N Komatsu, ... International Journal of Pharmaceutics 606, 120872, 2021 | 17 | 2021 |
Macrophages mediated delivery of chlorin e6 and treatment of lung cancer by photodynamic reprogramming TT Yu, XY Sang, N Han, XC Peng, QR Li, X Xu, RC Xiao, HZ Xu, X Chen, ... International Immunopharmacology 100, 108164, 2021 | 15 | 2021 |
Chlorin e6-induced photodynamic effect polarizes the macrophage into an M1 phenotype through oxidative DNA damage and activation of STING TT Yu, N Han, LG Li, XC Peng, QR Li, HZ Xu, XY Wang, ZY Yang, X Chen, ... Frontiers in Pharmacology 13, 837784, 2022 | 13 | 2022 |
A weakly supervised deep learning model and human–machine fusion for accurate grading of renal cell carcinoma from histopathology slides Q Zheng, R Yang, H Xu, J Fan, P Jiao, X Ni, J Yuan, L Wang, Z Chen, ... Cancers 15 (12), 3198, 2023 | 10 | 2023 |