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Huazhen Xu
Huazhen Xu
Johns Hopkins University
Verifisert e-postadresse på jh.edu
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A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin
XX Yang, X Xu, MF Wang, HZ Xu, XC Peng, N Han, TT Yu, LG Li, QR Li, ...
Journal of nanobiotechnology 20 (1), 230, 2022
532022
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer
SJ Yuan, YH Xu, C Wang, HC An, HZ Xu, K Li, N Komatsu, L Zhao, ...
Journal of Nanobiotechnology 17, 1-25, 2019
532019
Targeted photodynamic therapy of glioblastoma mediated by platelets with photo-controlled release property
HZ Xu, TF Li, Y Ma, K Li, Q Zhang, YH Xu, YC Zhang, L Zhao, X Chen
Biomaterials 290, 121833, 2022
442022
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy
N Han, ZY Yang, ZX Xie, HZ Xu, TT Yu, QR Li, LG Li, XC Peng, XX Yang, ...
Phytomedicine 112, 154682, 2023
432023
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancer through inhibiting GPX4 and enhancing ROS
N Han, LG Li, XC Peng, QL Ma, ZY Yang, XY Wang, J Li, QR Li, TT Yu, ...
European Journal of Pharmacology 919, 174797, 2022
432022
Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells
HZ Xu, TF Li, C Wang, Y Ma, Y Liu, MY Zheng, ZJY Liu, JB Chen, K Li, ...
Journal of Nanobiotechnology 19, 1-24, 2021
422021
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage
LG Li, XC Peng, TT Yu, HZ Xu, N Han, XX Yang, QR Li, J Hu, B Liu, ...
Frontiers in Pharmacology 13, 949835, 2022
382022
Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery
QR Li, HZ Xu, RC Xiao, Y Liu, JM Tang, J Li, TT Yu, B Liu, LG Li, MF Wang, ...
Drug Delivery 29 (1), 937-949, 2022
372022
Efficient delivery of chlorin e6 by polyglycerol-coated iron oxide nanoparticles with conjugated doxorubicin for enhanced photodynamic therapy of melanoma
TF Li, HZ Xu, YH Xu, TT Yu, JM Tang, K Li, C Wang, XC Peng, QR Li, ...
Molecular Pharmaceutics 18 (9), 3601-3615, 2021
352021
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes
Z Chen, SJ Yuan, K Li, Q Zhang, TF Li, HC An, HZ Xu, Y Yue, M Han, ...
Journal of Controlled Release 320, 469-483, 2020
282020
Surface-engineered carbon nanohorns as a theranostic nanodevice for photoacoustic imaging and effective radiochemotherapy of cancer
D Li, Y Zhang, J Xu, F Yoshino, H Xu, X Chen, L Zhao
Carbon 180, 185-196, 2021
272021
A dihydroartemisinin‐loaded nanoreactor motivates anti‐cancer immunotherapy by synergy‐induced ferroptosis to activate Cgas/STING for reprogramming of macrophage
LG Li, XX Yang, HZ Xu, TT Yu, QR Li, J Hu, XC Peng, N Han, X Xu, ...
Advanced Healthcare Materials 12 (28), 2301561, 2023
242023
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer
TT Yu, XC Peng, MF Wang, N Han, HZ Xu, QR Li, LG Li, X Xu, QL Ma, ...
Journal of Cancer Research and Clinical Oncology, 1-13, 2022
232022
Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells
QL Ma, MO Shen, N Han, HZ Xu, XC Peng, QR Li, TT Yu, LG Li, X Xu, ...
Photodiagnosis and Photodynamic Therapy 37, 102645, 2022
222022
Tumor Eradication by Boron Neutron Capture Therapy with 10B‐enriched Hexagonal Boron Nitride Nanoparticles Grafted with Poly(Glycerol)
Y Zhang, HG Kang, H Xu, H Luo, M Suzuki, Q Lan, X Chen, N Komatsu, ...
Advanced Materials 35 (35), 2301479, 2023
212023
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates
Z Chen, C Wang, TF Li, K Li, Y Yue, X Liu, HZ Xu, Y Wen, Q Zhang, M Han, ...
Nanomedicine 14 (3), 335-351, 2019
182019
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin
SJ Yuan, C Wang, HZ Xu, Y Liu, MY Zheng, K Li, SK Sun, N Komatsu, ...
International Journal of Pharmaceutics 606, 120872, 2021
172021
Macrophages mediated delivery of chlorin e6 and treatment of lung cancer by photodynamic reprogramming
TT Yu, XY Sang, N Han, XC Peng, QR Li, X Xu, RC Xiao, HZ Xu, X Chen, ...
International Immunopharmacology 100, 108164, 2021
152021
Chlorin e6-induced photodynamic effect polarizes the macrophage into an M1 phenotype through oxidative DNA damage and activation of STING
TT Yu, N Han, LG Li, XC Peng, QR Li, HZ Xu, XY Wang, ZY Yang, X Chen, ...
Frontiers in Pharmacology 13, 837784, 2022
132022
A weakly supervised deep learning model and human–machine fusion for accurate grading of renal cell carcinoma from histopathology slides
Q Zheng, R Yang, H Xu, J Fan, P Jiao, X Ni, J Yuan, L Wang, Z Chen, ...
Cancers 15 (12), 3198, 2023
102023
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