| PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation MZ Noman, G Desantis, B Janji, M Hasmim, S Karray, P Dessen, V Bronte, ... Journal of Experimental Medicine 211 (5), 781-790, 2014 | 2072 | 2014 |
| Hypoxia: a key player in antitumor immune response. A review in the theme: cellular responses to hypoxia MZ Noman, M Hasmim, Y Messai, S Terry, C Kieda, B Janji, S Chouaib American Journal of Physiology-Cell Physiology 309 (9), C569-C579, 2015 | 399 | 2015 |
| Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell–mediated lysis I Akalay, B Janji, M Hasmim, MZ Noman, F André, P De Cremoux, ... Cancer research 73 (8), 2418-2427, 2013 | 346 | 2013 |
| The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200 MZ Noman, B Janji, A Abdou, M Hasmim, S Terry, TZ Tan, ... Oncoimmunology 6 (1), e1263412, 2017 | 254 | 2017 |
| The cooperative induction of hypoxia-inducible factor-1α and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis MZ Noman, S Buart, J Van Pelt, C Richon, M Hasmim, N Leleu, ... The Journal of Immunology 182 (6), 3510-3521, 2009 | 227 | 2009 |
| Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy MZ Noman, S Parpal, K Van Moer, M Xiao, Y Yu, T Arakelian, J Viklund, ... Science advances 6 (18), eaax7881, 2020 | 213 | 2020 |
| Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase … M Bezzi, M Hasmim, G Bieler, O Dormond, C Rüegg Journal of Biological Chemistry 278 (44), 43603-43614, 2003 | 204 | 2003 |
| Hypoxia promotes tumor growth in linking angiogenesis to immune escape S Chouaib, Y Messai, S Couve, B Escudier, M Hasmim, MZ Noman Frontiers in immunology 3, 21, 2012 | 203 | 2012 |
| Improving cancer immunotherapy by targeting the hypoxic tumor microenvironment: new opportunities and challenges MZ Noman, M Hasmim, A Lequeux, M Xiao, C Duhem, S Chouaib, ... Cells 8 (9), 1083, 2019 | 187 | 2019 |
| ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy Y Messai, MZ Noman, M Hasmim, B Janji, A Tittarelli, M Boutet, V Baud, ... Cancer research 74 (23), 6820-6832, 2014 | 169 | 2014 |
| Renal cell carcinoma programmed death-ligand 1, a new direct target of hypoxia-inducible factor-2 alpha, is regulated by von Hippel–Lindau gene mutation status Y Messai, S Gad, MZ Noman, G Le Teuff, S Couve, B Janji, SF Kammerer, ... European urology 70 (4), 623-632, 2016 | 150 | 2016 |
| Critical role of tumor microenvironment in shaping NK cell functions: implication of hypoxic stress M Hasmim, Y Messai, L Ziani, J Thiery, JH Bouhris, MZ Noman, ... Frontiers in immunology 6, 482, 2015 | 149 | 2015 |
| Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response MZ Noman, Y Messai, T Carre, I Akalay, M Meron, B Janji, M Hasmim, ... Critical Reviews™ in Immunology 31 (5), 2011 | 126 | 2011 |
| Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1 M Hasmim, MZ Noman, Y Messai, D Bordereaux, G Gros, V Baud, ... The Journal of Immunology 191 (12), 5802-5806, 2013 | 119 | 2013 |
| Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation‐dependent signaling pathways M Hasmim, G Bieler, C Rüegg Journal of thrombosis and haemostasis 5 (1), 166-173, 2007 | 118 | 2007 |
| Antiangiogenic peptides and proteins: from experimental tools to clinical drugs C Rüegg, M Hasmim, FJ Lejeune, GC Alghisi Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1765 (2), 155-177, 2006 | 118 | 2006 |
| Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy A Lequeux, MZ Noman, M Xiao, K Van Moer, M Hasmim, A Benoit, ... Oncogene 40 (28), 4725-4735, 2021 | 101 | 2021 |
| Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints A Lequeux, MZ Noman, M Xiao, D Sauvage, K Van Moer, E Viry, I Bocci, ... Cancer Letters 458, 13-20, 2019 | 101 | 2019 |
| Immune surveillance of human cancer: if the cytotoxic T‐lymphocytes play the music, does the tumoral system call the tune? A Hamai, H Benlalam, F Meslin, M Hasmim, T Carre, I Akalay, B Janji, ... Tissue antigens 75 (1), 1-8, 2010 | 96 | 2010 |
| The multifaceted role of autophagy in tumor evasion from immune surveillance B Janji, E Viry, E Moussay, J Paggetti, T Arakelian, T Mgrditchian, ... Oncotarget 7 (14), 17591, 2016 | 76 | 2016 |
