The renaissance and bright future of synthetic aryne chemistry S Yoshida, T Hosoya Chemistry Letters 44 (11), 1450-1460, 2015 | 224 | 2015 |
Synthesis of 3-Trifluoromethylbenzo[b]furans from Phenols via Direct Ortho Functionalization by Extended Pummerer Reaction T Kobatake, D Fujino, S Yoshida, H Yorimitsu, K Oshima Journal of the American Chemical Society 132 (34), 11838-11840, 2010 | 155 | 2010 |
Single C−F Bond Cleavage of Trifluoromethylarenes with an ortho‐Silyl Group S Yoshida, K Shimomori, Y Kim, T Hosoya Angewandte Chemie 128 (35), 10562-10565, 2016 | 138 | 2016 |
Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia M Yoshida, N Kataoka, K Miyauchi, K Ohe, K Iida, S Yoshida, T Nojima, ... Proceedings of the National Academy of Sciences 112 (9), 2764-2769, 2015 | 132 | 2015 |
Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N-Arylation S Yoshida, T Yano, Y Misawa, Y Sugimura, K Igawa, S Shimizu, ... Journal of the American Chemical Society 137 (44), 14071-14074, 2015 | 131 | 2015 |
Strain-promoted double-click reaction for chemical modification of azido-biomolecules I Kii, A Shiraishi, T Hiramatsu, T Matsushita, H Uekusa, S Yoshida, ... Organic & Biomolecular Chemistry 8 (18), 4051-4055, 2010 | 122 | 2010 |
Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface Y Toyoda, K Morimoto, R Suno, S Horita, K Yamashita, K Hirata, ... Nature chemical biology 15 (1), 18-26, 2019 | 112 | 2019 |
A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates S Yoshida, Y Sugimura, Y Hazama, Y Nishiyama, T Yano, S Shimizu, ... Chemical Communications 51 (93), 16613-16616, 2015 | 104 | 2015 |
Reaction of 2‐(2, 2, 2‐Trifluoroethylidene)‐1, 3‐dithiane 1‐Oxide with Ketones under Pummerer Conditions and Its Application to the Synthesis of 3‐Trifluoromethyl‐Substituted … T Kobatake, S Yoshida, H Yorimitsu, K Oshima Angewandte Chemie 122 (13), 2390-2393, 2010 | 98 | 2010 |
Selective inhibition of the kinase DYRK1A by targeting its folding process I Kii, Y Sumida, T Goto, R Sonamoto, Y Okuno, S Yoshida, T Kato-Sumida, ... Nature communications 7 (1), 11391, 2016 | 95 | 2016 |
2-(2, 2, 2-Trifluoroethylidene)-1, 3-dithiane monoxide as a trifluoromethylketene equivalent S Yoshida, H Yorimitsu, K Oshima Organic Letters 11 (10), 2185-2188, 2009 | 94 | 2009 |
Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice A Nakano-Kobayashi, T Awaya, I Kii, Y Sumida, Y Okuno, S Yoshida, ... Proceedings of the National Academy of Sciences 114 (38), 10268-10273, 2017 | 91 | 2017 |
Enhanced clickability of doubly sterically-hindered aryl azides S Yoshida, A Shiraishi, K Kanno, T Matsushita, K Johmoto, H Uekusa, ... Scientific reports 1 (1), 1-4, 2011 | 90 | 2011 |
Synthesis of Benzo[b]thiophenes by Cyclization of Arylketene Dithioacetal Monoxides under Pummerer-like Conditions S Yoshida, H Yorimitsu, K Oshima Organic Letters 9 (26), 5573-5576, 2007 | 88 | 2007 |
Palladium-catalyzed regio-and stereoselective hydrosilylation of electron-deficient alkynes Y Sumida, T Kato, S Yoshida, T Hosoya Organic letters 14 (6), 1552-1555, 2012 | 86 | 2012 |
An efficient generation method and remarkable reactivities of 3-triflyloxybenzyne S Yoshida, K Uchida, K Igawa, K Tomooka, T Hosoya Chemical Communications 50 (95), 15059-15062, 2014 | 84 | 2014 |
Recent advances in reactions between arynes and organosulfur compounds T Matsuzawa, S Yoshida, T Hosoya Tetrahedron Letters 59 (48), 4197-4208, 2018 | 83 | 2018 |
CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses M Yamamoto, H Onogi, I Kii, S Yoshida, K Iida, H Sakai, M Abe, T Tsubota, ... The Journal of clinical investigation 124 (8), 3479-3488, 2014 | 81 | 2014 |
C6-deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase S Inouye, J Sato, Y Sahara-Miura, S Yoshida, H Kurakata, T Hosoya Biochemical and biophysical research communications 437 (1), 23-28, 2013 | 74 | 2013 |
Synthesis of diverse aromatic oxophosphorus compounds by the Michaelis–Arbuzov-type reaction of arynes S Yoshida, T Hosoya Chemistry Letters 42 (6), 583-585, 2013 | 74 | 2013 |