| Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis M Bambouskova, L Gorvel, V Lampropoulou, A Sergushichev, ... Nature 556 (7702), 501-504, 2018 | 602 | 2018 |
| Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages A Swain, M Bambouskova, H Kim, PS Andhey, D Duncan, K Auclair, ... Nature metabolism 2 (7), 594-602, 2020 | 243 | 2020 |
| Enzymatic depolymerization of highly crystalline polyethylene terephthalate enabled in moist-solid reaction mixtures S Kaabel, JPD Therien, CE Deschênes, D Duncan, T Friščić, K Auclair Proceedings of the National Academy of Sciences 118 (29), e2026452118, 2021 | 103 | 2021 |
| AI is a viable alternative to high throughput screening: a 318-target study Scientific reports 14 (1), 7526, 2024 | 34 | 2024 |
| Effect of pH on the antimicrobial activity of the macrophage metabolite itaconate D Duncan, A Lupien, MA Behr, K Auclair Microbiology 167 (5), 001050, 2021 | 22 | 2021 |
| Small Molecule Restores Itaconate Sensitivity in Salmonella enterica: A Potential New Approach to Treating Bacterial Infections F Hammerer, JH Chang, D Duncan, A Castañeda Ruiz, K Auclair Chembiochem 17 (16), 1513-1517, 2016 | 22 | 2016 |
| Exploring heteroaromatic rings as a replacement for the labile amide of antiplasmodial pantothenamides J Guan, C Spry, ET Tjhin, P Yang, T Kittikool, VM Howieson, H Ling, ... Journal of Medicinal Chemistry 64 (8), 4478-4497, 2021 | 17 | 2021 |
| Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity KR Iyer, SC Li, NM Revie, JW Lou, D Duncan, S Fallah, H Sanchez, ... Cell chemical biology 30 (7), 795-810. e8, 2023 | 14 | 2023 |
| Chemical-genetic identification of the biochemical targets of polyalkyl guanidinium biocides D Bowie, P Parvizi, D Duncan, CJ Nelson, TM Fyles Organic & Biomolecular Chemistry 11 (26), 4359-4366, 2013 | 10 | 2013 |
| Inhibiting C-4 Methyl Sterol Oxidase with Novel Diazaborines to Target Fungal Plant Pathogens SH Kim, L Steere, YK Zhang, C McGregor, C Hahne, Y Zhou, C Liu, Y Cai, ... ACS Chemical Biology 17 (6), 1343-1350, 2022 | 9 | 2022 |
| The coenzyme A biosynthetic pathway: A new tool for prodrug bioactivation D Duncan, K Auclair Archives of Biochemistry and Biophysics 672, 108069, 2019 | 8 | 2019 |
| Introduction to Ligand Design in Medicinal Inorganic Chemistry MR Jones, D Duncan, T Storr Ligand Design in Medicinal Inorganic Chemistry, 1-8, 2014 | 8 | 2014 |
| Reversible Covalent Inhibition─ Desired Covalent Adduct Formation by Mass Action D Patel, ZE Huma, D Duncan ACS Chemical Biology 19 (4), 824-838, 2024 | 7 | 2024 |
| The trisubstituted Isoxazole MMV688766 exerts broad-spectrum activity against drug-resistant fungal pathogens through inhibition of lipid homeostasis E Puumala, O Zaslaver, A Chen, D Duncan, M Fogal, RS Shapiro, ... MBio 13 (6), e02730-22, 2022 | 5 | 2022 |
| Clean enzymatic depolymerization of highly crystalline polyethylene terephthalate in moist-solid reaction mixtures S Kaabel, JPD Therien, CE Deschênes, D Duncan, T Friščić, K Auclair BioRxiv, 2020.07. 06.189720, 2020 | 5 | 2020 |
| Potent Antifungal Activity of Penta-O-galloyl-β-d-Glucose against Drug-Resistant Candida albicans, Candida auris, and Other Non-albicans Candida Species L Marquez, Y Lee, D Duncan, L Whitesell, LE Cowen, C Quave ACS Infectious Diseases 9 (9), 1685-1694, 2023 | 4 | 2023 |
| Itaconate: an antimicrobial metabolite of macrophages D Duncan, K Auclair Canadian Journal of Chemistry 100 (2), 104-113, 2022 | 4 | 2022 |
| A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans S Fallah, D Duncan, KD Reichl, MJ Smith, W Wang, JA Porco Jr, ... Microbiology Spectrum 12 (4), e04095-23, 2024 | 3 | 2024 |
| The antimicrobial activity of the macrophage metabolite itaconate is synergistic with acidity D Duncan, A Lupien, MA Behr, K Auclair bioRxiv, 2020.08. 05.238311, 2020 | 1 | 2020 |
| Small molecule restores itaconate sensitivity in Salmonella enterica: a potential new approach to treat bacterial infections F Hammerer, JH Chang, D Duncan, A Castañeda Ruiz, K Auclair | 1 | 2016 |