Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network KM Holmes, M Annala, CYX Chua, SM Dunlap, Y Liu, N Hugen, ... Proceedings of the National Academy of Sciences 109 (9), 3475-3480, 2012 | 125 | 2012 |
IGFBP2 activates the NF-κB pathway to drive epithelial–mesenchymal transition and invasive character in pancreatic ductal adenocarcinoma S Gao, Y Sun, X Zhang, L Hu, Y Liu, CY Chua, LM Phillips, H Ren, ... Cancer research 76 (22), 6543-6554, 2016 | 106 | 2016 |
Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis CYX Chua, P Jain, A Ballerini, G Bruno, RL Hood, M Gupte, S Gao, ... Journal of controlled release 286, 315-325, 2018 | 86 | 2018 |
IGFBP2 potentiates nuclear EGFR–STAT3 signaling CY Chua, Y Liu, KJ Granberg, L Hu, H Haapasalo, MJ Annala, ... Oncogene 35 (6), 738-747, 2016 | 82 | 2016 |
Advanced strategies to thwart foreign body response to implantable devices S Capuani, G Malgir, CYX Chua, A Grattoni Bioengineering & Translational Medicine 7 (3), e10300, 2022 | 76 | 2022 |
Carbon fiber reinforced polymers for implantable medical devices CYX Chua, HC Liu, N Di Trani, A Susnjar, J Ho, G Scorrano, J Rhudy, ... Biomaterials 271, 120719, 2021 | 75 | 2021 |
Emerging technologies for local cancer treatment CYX Chua, J Ho, S Demaria, M Ferrari, A Grattoni Advanced therapeutics 3 (9), 2000027, 2020 | 67 | 2020 |
Nanofluidic drug-eluting seed for sustained intratumoral immunotherapy in triple negative breast cancer CYX Chua, P Jain, A Susnjar, J Rhudy, M Folci, A Ballerini, A Gilbert, ... Journal of Controlled Release 285, 23-34, 2018 | 60 | 2018 |
Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells M Farina, CYX Chua, A Ballerini, U Thekkedath, JF Alexander, JR Rhudy, ... Biomaterials 177, 125-138, 2018 | 60 | 2018 |
Potentiating antitumor efficacy through radiation and sustained intratumoral delivery of anti-CD40 and anti-PDL1 HC Liu, DI Viswanath, F Pesaresi, Y Xu, L Zhang, N Di Trani, ... International Journal of Radiation Oncology* Biology* Physics 110 (2), 492-506, 2021 | 59 | 2021 |
2-Hydroxypropyl-β-cyclodextrin-enhanced pharmacokinetics of cabotegravir from a nanofluidic implant for HIV pre-exposure prophylaxis FP Pons-Faudoa, A Sizovs, N Di Trani, J Paez-Mayorga, G Bruno, ... Journal of Controlled Release 306, 89-96, 2019 | 52 | 2019 |
Remotely controlled nanofluidic implantable platform for tunable drug delivery N Di Trani, A Silvestri, G Bruno, T Geninatti, CYX Chua, A Gilbert, G Rizzo, ... Lab on a Chip 19 (13), 2192-2204, 2019 | 52 | 2019 |
Emerging biomaterial-based strategies for personalized therapeutic in situ cancer vaccines DI Viswanath, HC Liu, DP Huston, CYX Chua, A Grattoni Biomaterials 280, 121297, 2022 | 51 | 2022 |
Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti‐IGFBP2 strategies LM Phillips, X Zhou, DE Cogdell, CY Chua, A Huisinga, K R Hess, ... The Journal of pathology 239 (3), 355-364, 2016 | 50 | 2016 |
Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV‐challenged nonhuman primates FP Pons‐Faudoa, A Sizovs, KA Shelton, Z Momin, JA Niles, LR Bushman, ... Advanced therapeutics 4 (3), 2000163, 2021 | 49 | 2021 |
Adipocytes impair efficacy of antiretroviral therapy J Couturier, LC Winchester, JW Suliburk, GK Wilkerson, AT Podany, ... Antiviral research 154, 140-148, 2018 | 49 | 2018 |
Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats J Paez-Mayorga, JN Campa-Carranza, S Capuani, N Hernandez, HC Liu, ... Nature communications 13 (1), 7951, 2022 | 41 | 2022 |
Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation J Paez-Mayorga, S Capuani, N Hernandez, M Farina, CYX Chua, ... Biomaterials 257, 120232, 2020 | 38 | 2020 |
Nanofluidic microsystem for sustained intraocular delivery of therapeutics N Di Trani, P Jain, CYX Chua, JS Ho, G Bruno, A Susnjar, ... Nanomedicine: Nanotechnology, Biology and Medicine 16, 1-9, 2019 | 35 | 2019 |
Enhanced in vivo vascularization of 3D‐printed cell encapsulation device using platelet‐rich plasma and mesenchymal stem cells J Paez‐Mayorga, S Capuani, M Farina, ML Lotito, JA Niles, HF Salazar, ... Advanced Healthcare Materials 9 (19), 2000670, 2020 | 30 | 2020 |