| Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis N Kosaka, H Iguchi, K Hagiwara, Y Yoshioka, F Takeshita, T Ochiya Journal of Biological Chemistry 288 (15), 10849-10859, 2013 | 869 | 2013 |
| Competitive interactions of cancer cells and normal cells via secretory microRNAs N Kosaka, H Iguchi, Y Yoshioka, K Hagiwara, F Takeshita, T Ochiya Journal of Biological Chemistry 287 (2), 1397-1405, 2012 | 339 | 2012 |
| Conversion of terminally committed hepatocytes to culturable bipotent progenitor cells with regenerative capacity T Katsuda, M Kawamata, K Hagiwara, R Takahashi, Y Yamamoto, ... Cell stem cell 20 (1), 41-55, 2017 | 262 | 2017 |
| The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer Y Fujita, S Yagishita, K Hagiwara, Y Yoshioka, N Kosaka, F Takeshita, ... Molecular therapy 23 (4), 717-727, 2015 | 260 | 2015 |
| Olive polyphenol hydroxytyrosol prevents bone loss K Hagiwara, T Goto, M Araki, H Miyazaki, H Hagiwara European journal of pharmacology 662 (1-3), 78-84, 2011 | 191 | 2011 |
| Trash or Treasure: extracellular microRNAs and cell-to-cell communication N Kosaka, Y Yoshioka, K Hagiwara, N Tominaga, T Katsuda, T Ochiya Frontiers in genetics 4, 173, 2013 | 187 | 2013 |
| Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity K Hagiwara, N Kosaka, Y Yoshioka, R Takahashi, F Takeshita, T Ochiya Scientific reports 2 (1), 314, 2012 | 165 | 2012 |
| miR‐148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells L Gailhouste, L Gomez‐Santos, K Hagiwara, I Hatada, N Kitagawa, ... Hepatology 58 (3), 1153-1165, 2013 | 150 | 2013 |
| RPN2-mediated glycosylation of tetraspanin CD63 regulates breast cancer cell malignancy N Tominaga, K Hagiwara, N Kosaka, K Honma, H Nakagama, T Ochiya Molecular cancer 13, 1-11, 2014 | 132 | 2014 |
| Stem cells for hepatic regeneration: the role of adipose tissue derived mesenchymal stem cells T Ishikawa, A Banas, K Hagiwara, H Iwaguro, T Ochiya Current Stem Cell Research & Therapy 5 (2), 182-189, 2010 | 114 | 2010 |
| Commitment of Annexin A2 in recruitment of microRNAs into extracellular vesicles K Hagiwara, T Katsuda, L Gailhouste, N Kosaka, T Ochiya FEBS letters 589 (24), 4071-4078, 2015 | 111 | 2015 |
| Exosomal tumor-suppressive microRNAs as novel cancer therapy:“exocure” is another choice for cancer treatment N Kosaka, F Takeshita, Y Yoshioka, K Hagiwara, T Katsuda, M Ono, ... Advanced drug delivery reviews 65 (3), 376-382, 2013 | 93 | 2013 |
| Apigenin inhibits osteoblastogenesis and osteoclastogenesis and prevents bone loss in ovariectomized mice T Goto, K Hagiwara, N Shirai, K Yoshida, H Hagiwara Cytotechnology 67, 357-365, 2015 | 91 | 2015 |
| Clinical relevance and therapeutic significance of microRNA-133a expression profiles and functions in malignant osteosarcoma-initiating cells T Fujiwara, T Katsuda, K Hagiwara, N Kosaka, Y Yoshioka, RU Takahashi, ... Stem cells 32 (4), 959-973, 2014 | 86 | 2014 |
| Dark side of the exosome: the role of the exosome in cancer metastasis and targeting the exosome as a strategy for cancer therapy N Kosaka, Y Yoshioka, N Tominaga, K Hagiwara, T Katsuda, T Ochiya Future Oncology 10 (4), 671-681, 2014 | 68 | 2014 |
| miR-135b, a key regulator of malignancy, is linked to poor prognosis in human myxoid liposarcoma Y Nezu, K Hagiwara, Y Yamamoto, T Fujiwara, K Matsuo, A Yoshida, ... Oncogene 35 (48), 6177-6188, 2016 | 57 | 2016 |
| A paradigm shift for extracellular vesicles as small RNA carriers: from cellular waste elimination to therapeutic applications K Hagiwara, T Ochiya, N Kosaka Drug delivery and translational research 4, 31-37, 2014 | 52 | 2014 |
| Functional analysis of exosomal microRNA in cell–cell communication research N Kosaka, Y Yoshioka, K Hagiwara, N Tominaga, T Ochiya Circulating MicroRNAs: Methods and Protocols, 1-10, 2013 | 43 | 2013 |
| miR-34a-5p might have an important role for inducing apoptosis by down-regulation of SNAI1 in apigenin-treated lung cancer cells R Aida, K Hagiwara, K Okano, K Nakata, Y Obata, T Yamashita, ... Molecular Biology Reports 48, 2291-2297, 2021 | 33 | 2021 |
| MicroRNA‐493‐5p‐mediated repression of the MYCN oncogene inhibits hepatic cancer cell growth and invasion K Yasukawa, LC Liew, K Hagiwara, A Hironaka‐Mitsuhashi, XY Qin, ... Cancer science 111 (3), 869-880, 2020 | 31 | 2020 |
