Lewis Cantley

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John AsaraAssociate Professor Medicine, Harvard Medical School; Director, Beth Israel Deaconess Medical CenterVerifisert e-postadresse på bidmc.harvard.edu
Costas LyssiotisProfessor of Physiology, University of MichiganVerifisert e-postadresse på lyssiotis.com
Ji LuoNational Cancer InstituteVerifisert e-postadresse på nih.gov
David FrumanProfessor of Molecular Biology & Biochemistry, UC IrvineVerifisert e-postadresse på uci.edu
John BlenisProfessor of Pharmacology, Weill Cornell MedicineVerifisert e-postadresse på med.cornell.edu
Alex TokerVerifisert e-postadresse på bidmc.harvard.edu
Jason LocasaleDuke UniversityVerifisert e-postadresse på alum.mit.edu
Brendan D. ManningHarvard UniversityVerifisert e-postadresse på hsph.harvard.edu
Lucia Rameh PlantVanderbilt UniversityVerifisert e-postadresse på vanderbilt.edu
C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolVerifisert e-postadresse på joslin.harvard.edu
Reuben ShawThe Salk Institute of Biological StudiesVerifisert e-postadresse på salk.edu
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterVerifisert e-postadresse på bidmc.harvard.edu
David R. KaplanHospital for Sick ChildrenVerifisert e-postadresse på sickkids.ca
Ronald A. DePinhoMD AndersonVerifisert e-postadresse på mdanderson.org
Steven ShoelsonHarvard Medical SchoolVerifisert e-postadresse på joslin.harvard.edu
Gerburg WulfAssociate Professor in Medicine, Harvard Medical SchoolVerifisert e-postadresse på bidmc.harvard.edu
Kurt AugerGSKVerifisert e-postadresse på gsk.com
Marcus D GoncalvesWeill Cornell New York Presbyterian HospitalVerifisert e-postadresse på med.cornell.edu
Benjamin D. HopkinsWeill Cornell MedicineVerifisert e-postadresse på med.cornell.edu
Malcolm WhitmanHarvardVerifisert e-postadresse på hms.harvard.edu

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Lewis Cantley

Dana Farber Cancer Center and Harvard Medical School

Verifisert e-postadresse på med.cornell.edu

cancer metabolism signal transduction PI 3-Kinase Protein kinases


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Understanding the Warburg effect: the metabolic requirements of cell proliferation MG Vander Heiden, LC Cantley, CB Thompson science 324 (5930), 1029-1033, 2009	17551	2009
AKT/PKB signaling: navigating downstream BD Manning, LC Cantley Cell 129 (7), 1261-1274, 2007	7562	2007
The phosphoinositide 3-kinase pathway LC Cantley Science 296 (5573), 1655-1657, 2002	7429	2002
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ... science 316 (5827), 1039-1043, 2007	5511	2007
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ... Nature 462 (7274), 739-744, 2009	4857	2009
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism JA Engelman, J Luo, LC Cantley Nature Reviews Genetics 7 (8), 606-619, 2006	4053	2006
SH2 domains recognize specific phosphopeptide sequences S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ... Cell 72 (5), 767-778, 1993	3567	1993
Oncogenes and signal transduction LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ... Cell 64 (2), 281-302, 1991	3552	1991
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ... Nature 452 (7184), 230-233, 2008	3291	2008
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011	2959*	2011
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway LC Cantley, BG Neel Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999	2764	1999
Ras, PI (3) K and mTOR signalling controls tumour cell growth RJ Shaw, LC Cantley Nature 441 (7092), 424-430, 2006	2655	2006
The PI3K pathway in human disease DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham Cell 170 (4), 605-635, 2017	2461	2017
PI3K pathway alterations in cancer: variations on a theme TL Yuan, LC Cantley Oncogene 27 (41), 5497-5510, 2008	2451	2008
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ... Science 310 (5754), 1642-1646, 2005	2421	2005
PI3K: downstream AKTion blocks apoptosis TF Franke, DR Kaplan, LC Cantley Cell 88 (4), 435-437, 1997	2195	1997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ... Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004	2178	2004
Phosphoinositide kinases DA Fruman, RE Meyers, LC Cantley Annual review of biochemistry 67 (1), 481-507, 1998	2155	1998
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ... Cell 149 (3), 656-670, 2012	2137	2012
Bidirectional transport of amino acids regulates mTOR and autophagy P Nicklin, P Bergman, B Zhang, E Triantafellow, H Wang, B Nyfeler, ... Cell 136 (3), 521-534, 2009	2045	2009

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