The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers D Hu, X Gao, MA Morgan, HM Herz, ER Smith, A Shilatifard Molecular and cellular biology 33 (23), 4745-4754, 2013 | 454 | 2013 |
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas A Piunti, R Hashizume, MA Morgan, ET Bartom, CM Horbinski, ... Nature medicine 23 (4), 493-500, 2017 | 406 | 2017 |
Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation MAJ Morgan, A Shilatifard Nature genetics 52 (12), 1271-1281, 2020 | 304 | 2020 |
Chromatin signatures of cancer MA Morgan, A Shilatifard Genes & development 29 (3), 238-249, 2015 | 267 | 2015 |
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability R Rickels, HM Herz, CC Sze, K Cao, MA Morgan, CK Collings, M Gause, ... Nature genetics 49 (11), 1647-1653, 2017 | 224 | 2017 |
The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells D Hu, AS Garruss, X Gao, MA Morgan, M Cook, ER Smith, A Shilatifard Nature structural & molecular biology 20 (9), 1093-1097, 2013 | 214 | 2013 |
Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling HM Herz, M Morgan, X Gao, J Jackson, R Rickels, SK Swanson, L Florens, ... Science 345 (6200), 1065-1070, 2014 | 206 | 2014 |
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy L Wang, Z Zhao, PA Ozark, D Fantini, SA Marshall, EJ Rendleman, ... Nature medicine 24 (6), 758-769, 2018 | 166 | 2018 |
Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice EJ Robertson, I Charatsi, CJ Joyner, CH Koonce, M Morgan, A Islam, ... Oxford University Press for The Company of Biologists Limited 134 (24), 4335 …, 2007 | 151 | 2007 |
An expanding job description for Blimp-1/PRDM1 EK Bikoff, MA Morgan, EJ Robertson Current opinion in genetics & development 19 (4), 379-385, 2009 | 125 | 2009 |
TET2 coactivates gene expression through demethylation of enhancers LU Wang, PA Ozark, ER Smith, Z Zhao, SA Marshall, EJ Rendleman, ... Science advances 4 (11), eaau6986, 2018 | 118 | 2018 |
Not all H3K4 methylations are created equal: Mll2/COMPASS dependency in primordial germ cell specification D Hu, X Gao, K Cao, MA Morgan, G Mas, ER Smith, AG Volk, ET Bartom, ... Molecular cell 65 (3), 460-475. e6, 2017 | 103 | 2017 |
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism A Piunti, ER Smith, MAJ Morgan, M Ugarenko, N Khaltyan, KA Helmin, ... Science advances 5 (7), eaax2887, 2019 | 101 | 2019 |
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation D Douillet, CC Sze, C Ryan, A Piunti, AP Shah, M Ugarenko, SA Marshall, ... Nature genetics 52 (6), 615-625, 2020 | 98 | 2020 |
Histone H3K4 methylation-dependent and-independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation CC Sze, K Cao, CK Collings, SA Marshall, EJ Rendleman, PA Ozark, ... Genes & development 31 (17), 1732-1737, 2017 | 98 | 2017 |
Inactivation of Ezh2 upregulates Gfi1 and drives aggressive Myc-driven group 3 medulloblastoma BHT Vo, C Li, MA Morgan, I Theurillat, D Finkelstein, S Wright, J Hyle, ... Cell reports 18 (12), 2907-2917, 2017 | 83 | 2017 |
Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta A Mould, MAJ Morgan, L Li, EK Bikoff, EJ Robertson Genes & development 26 (18), 2063-2074, 2012 | 79 | 2012 |
An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells K Cao, CK Collings, MA Morgan, SA Marshall, EJ Rendleman, PA Ozark, ... Science advances 4 (1), eaap8747, 2018 | 76 | 2018 |
Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation MAJ Morgan, E Magnusdottir, TC Kuo, C Tunyaplin, J Harper, SJ Arnold, ... Molecular and cellular biology 29 (21), 5813-5827, 2009 | 72 | 2009 |
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation MAJ Morgan, RA Rickels, CK Collings, X He, K Cao, HM Herz, ... Genes & development 31 (19), 2003-2014, 2017 | 71 | 2017 |