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Samuel Collombet
Samuel Collombet
Eikon Therapeutics
Verifisert e-postadresse på eikontx.com
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Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming
R Stadhouders, E Vidal, F Serra, B Di Stefano, F Le Dily, J Quilez, ...
Nature genetics 50 (2), 238-249, 2018
3532018
C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells
B Di Stefano, JL Sardina, C van Oevelen, S Collombet, EM Kallin, ...
Nature 506 (7487), 235-239, 2014
2472014
Transcription factors drive Tet2-mediated enhancer demethylation to reprogram cell fate
JL Sardina, S Collombet, TV Tian, A Gómez, B Di Stefano, C Berenguer, ...
Cell stem cell 23 (5), 727-741. e9, 2018
2442018
RSAT 2018: regulatory sequence analysis tools 20th anniversary
NTT Nguyen, B Contreras-Moreira, JA Castro-Mondragon, ...
Nucleic acids research 46 (W1), W209-W214, 2018
2122018
SPEN integrates transcriptional and epigenetic control of X-inactivation
F Dossin, I Pinheiro, JJ Żylicz, J Roensch, S Collombet, A Le Saux, ...
Nature 578 (7795), 455-460, 2020
1882020
Gene regulation in time and space during X-chromosome inactivation
A Loda, S Collombet, E Heard
Nature Reviews Molecular Cell Biology 23 (4), 231-249, 2022
1812022
Parental-to-embryo switch of chromosome organization in early embryogenesis
S Collombet, N Ranisavljevic, T Nagano, C Varnai, T Shisode, W Leung, ...
Nature 580 (7801), 142-146, 2020
1492020
Logical modeling of lymphoid and myeloid cell specification and transdifferentiation
S Collombet, C Van Oevelen, JL Sardina Ortega, W Abou-Jaoudé, ...
Proceedings of the National Academy of Sciences 114 (23), 5792-5799, 2017
1412017
C/EBPα activates pre-existing and de novo macrophage enhancers during induced pre-B cell transdifferentiation and myelopoiesis
C van Oevelen, S Collombet, G Vicent, M Hoogenkamp, C Lepoivre, ...
Stem cell reports 5 (2), 232-247, 2015
1292015
C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4
B Di Stefano, S Collombet, JS Jakobsen, M Wierer, JL Sardina, A Lackner, ...
Nature cell biology 18 (4), 371-381, 2016
1232016
Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming
A Janiszewski, I Talon, J Chappell, S Collombet, J Song, N De Geest, ...
Genome research 29 (10), 1659-1672, 2019
472019
Constitutively active SMAD2/3 are broad-scope potentiators of transcription-factor-mediated cellular reprogramming
T Ruetz, U Pfisterer, B Di Stefano, J Ashmore, M Beniazza, TV Tian, ...
Cell stem cell 21 (6), 791-805. e9, 2017
452017
RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization
S Collombet, I Rall, C Dugast-Darzacq, A Heckert, A Halavatyi, A Le Saux, ...
Nature Structural & Molecular Biology 30 (8), 1216-1223, 2023
352023
ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα
D Gonzalez, A Luyten, B Bartholdy, Q Zhou, M Kardosova, A Ebralidze, ...
Journal of Biological Chemistry 292 (46), 18924-18936, 2017
242017
Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation
P Torbey, E Thierion, S Collombet, A de Cian, C Desmarquet-Trin-Dinh, ...
PLoS genetics 14 (8), e1007581, 2018
222018
Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements
E Thierion, J Le Men, S Collombet, C Hernandez, F Coulpier, P Torbey, ...
PLoS genetics 13 (7), e1006903, 2017
212017
A transcription factor pulse can prime chromatin for heritable transcriptional memory
A Iberg-Badeaux, S Collombet, B Laurent, C van Oevelen, KK Chin, ...
Molecular and cellular biology 37 (4), e00372-16, 2017
172017
Logical modeling of cell fate specification—Application to T cell commitment
E Cacace, S Collombet, D Thieffry
Current Topics in Developmental Biology 139, 205-238, 2020
122020
Time-resolved gene expression profiling during reprogramming of C/EBPα-pulsed B cells into iPS cells
B Di Stefano, S Collombet, T Graf
Scientific data 1 (1), 1-8, 2014
72014
Bioinformatic Analysis of Single-Cell Hi-C Data from Early Mouse Embryo
S Collombet, YA Pérez-Rico, K Ancelin, N Servant, E Heard
Epigenetic Reprogramming During Mouse Embryogenesis: Methods and Protocols …, 2021
12021
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