| A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 1942 | 2016 |
| A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014 | 811 | 2014 |
| The IntAct molecular interaction database in 2010 B Aranda, P Achuthan, Y Alam-Faruque, I Armean, A Bridge, C Derow, ... Nucleic acids research 38 (suppl_1), D525-D531, 2010 | 800 | 2010 |
| Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ... PLoS one 8 (4), e61318, 2013 | 591 | 2013 |
| A community computational challenge to predict the activity of pairs of compounds M Bansal, J Yang, C Karan, MP Menden, JC Costello, H Tang, G Xiao, ... Nature biotechnology 32 (12), 1213-1222, 2014 | 342 | 2014 |
| Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ... Nature communications 10 (1), 2674, 2019 | 336 | 2019 |
| Pharmacogenomic agreement between two cancer cell line data sets Cancer Cell Line Encyclopedia Consortium, ... Nature 528 (7580), 84-87, 2015 | 301 | 2015 |
| Transcriptional data: a new gateway to drug repositioning? F Iorio, T Rittman, H Ge, M Menden, J Saez-Rodriguez Drug discovery today 18 (7-8), 350-357, 2013 | 288 | 2013 |
| Prediction of human population responses to toxic compounds by a collaborative competition F Eduati, LM Mangravite, T Wang, H Tang, JC Bare, R Huang, T Norman, ... Nature biotechnology 33 (9), 933-940, 2015 | 122 | 2015 |
| Artificial intelligence in early drug discovery enabling precision medicine F Boniolo, E Dorigatti, AJ Ohnmacht, D Saur, B Schubert, MP Menden Expert Opinion on Drug Discovery 16 (9), 991-1007, 2021 | 107 | 2021 |
| Applying synergy metrics to combination screening data: agreements, disagreements and pitfalls AHC Vlot, N Aniceto, MP Menden, G Ulrich-Merzenich, A Bender Drug discovery today 24 (12), 2286-2298, 2019 | 89 | 2019 |
| Adaptive informatics for multifactorial and high-content biological data BL Millard, M Niepel, MP Menden, JL Muhlich, PK Sorger Nature methods 8 (6), 487-492, 2011 | 81 | 2011 |
| Generative artificial intelligence empowers digital twins in drug discovery and clinical trials M Bordukova, N Makarov, R Rodriguez-Esteban, F Schmich, MP Menden Expert opinion on drug discovery 19 (1), 33-42, 2024 | 79 | 2024 |
| Quantitative proteome landscape of the NCI-60 cancer cell lines T Guo, A Luna, VN Rajapakse, CC Koh, Z Wu, W Liu, Y Sun, H Gao, ... Iscience 21, 664-680, 2019 | 63* | 2019 |
| GDSCTools for mining pharmacogenomic interactions in cancer T Cokelaer, E Chen, F Iorio, MP Menden, H Lightfoot, J Saez-Rodriguez, ... Bioinformatics 34 (7), 1226-1228, 2018 | 63 | 2018 |
| SLFN11 informs on standard of care and novel treatments in a wide range of cancer models C Winkler, J Armenia, GN Jones, L Tobalina, MJ Sale, T Petreus, T Baird, ... British journal of cancer 124 (5), 951-962, 2021 | 60 | 2021 |
| Machine learning and pharmacometrics for prediction of pharmacokinetic data: differences, similarities and challenges illustrated with rifampicin L Keutzer, H You, A Farnoud, J Nyberg, SG Wicha, G Maher-Edwards, ... Pharmaceutics 14 (8), 1530, 2022 | 55 | 2022 |
| Stratification and prediction of drug synergy based on target functional similarity M Yang, P Jaaks, J Dry, M Garnett, MP Menden, J Saez-Rodriguez NPJ systems biology and applications 6 (1), 16, 2020 | 50 | 2020 |
| The germline genetic component of drug sensitivity in cancer cell lines MP Menden, FP Casale, J Stephan, GR Bignell, F Iorio, U McDermott, ... Nature communications 9 (1), 3385, 2018 | 47 | 2018 |
| Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseases A Schäbitz, C Hillig, M Mubarak, M Jargosch, A Farnoud, E Scala, ... Nature Communications 13 (1), 7729, 2022 | 44 | 2022 |