Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases NN Rahbari, D Kedrin, J Incio, H Liu, WW Ho, HT Nia, CM Edrich, K Jung, ... Science translational medicine 8 (360), 360ra135-360ra135, 2016 | 241 | 2016 |
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium G Seano, HT Nia, KE Emblem, M Datta, J Ren, S Krishnan, J Kloepper, ... Nature biomedical engineering 3 (3), 230-245, 2019 | 192 | 2019 |
Roles of macrophages in tumor development: a spatiotemporal perspective M Bied, WW Ho, F Ginhoux, C Blériot Cellular & molecular immunology 20 (9), 983-992, 2023 | 129 | 2023 |
Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer K Jung, T Heishi, J Incio, Y Huang, EY Beech, M Pinter, WW Ho, ... Proceedings of the National Academy of Sciences 114 (39), 10455-10460, 2017 | 124 | 2017 |
Exercise Training Improves Tumor Control by Increasing CD8+ T-cell Infiltration via CXCR3 Signaling and Sensitizes Breast Cancer to Immune Checkpoint Blockade IL Gomes-Santos, Z Amoozgar, AS Kumar, WW Ho, K Roh, NP Talele, ... Cancer immunology research 9 (7), 765-778, 2021 | 102 | 2021 |
Use of angiotensin system inhibitors is associated with immune activation and longer survival in nonmetastatic pancreatic ductal adenocarcinoma H Liu, K Naxerova, M Pinter, J Incio, H Lee, K Shigeta, WW Ho, JA Crain, ... Clinical Cancer Research 23 (19), 5959-5969, 2017 | 95 | 2017 |
Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy DG Millar, RR Ramjiawan, K Kawaguchi, N Gupta, J Chen, S Zhang, ... Nature biotechnology 38 (4), 420-425, 2020 | 71 | 2020 |
Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy WW Ho, IL Gomes-Santos, S Aoki, M Datta, K Kawaguchi, NP Talele, ... Proceedings of the National Academy of Sciences 118 (45), e2105323118, 2021 | 66 | 2021 |
In vivo compression and imaging in mouse brain to measure the effects of solid stress HT Nia, M Datta, G Seano, S Zhang, WW Ho, S Roberge, P Huang, ... Nature protocols, 1-20, 2020 | 47 | 2020 |
Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models L Wu, S Vasilijic, Y Sun, J Chen, LD Landegger, Y Zhang, W Zhou, J Ren, ... Science translational medicine 13 (602), eabd4816, 2021 | 34 | 2021 |
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models M Datta, S Chatterjee, EM Perez, S Gritsch, S Roberge, M Duquette, ... Proceedings of the National Academy of Sciences 120 (6), e2219199120, 2023 | 30 | 2023 |
The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy WW Ho, MJ Pittet, D Fukumura, RK Jain Cancer Cell 40 (7), 701-702, 2022 | 28 | 2022 |
Cancer cell plasticity and MHC-II–mediated immune tolerance promote breast cancer metastasis to lymph nodes PJ Lei, ER Pereira, P Andersson, Z Amoozgar, JW Van Wijnbergen, ... Journal of Experimental Medicine 220 (9), e20221847, 2023 | 27 | 2023 |
Exercise training improves tumor control by increasing CD8 (+) t-cell infiltration via CXCR3 signaling and sensitizes breast cancer to immune checkpoint blockade. Cancer … IL Gomes-Santos, Z Amoozgar, AS Kumar, WW Ho, K Roh, NP Talele, ... CIR-20-0499.[DOI][PMC free article][PubMed][Academic Search], 0 | 10 | |
Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain Z Yin, L Wu, Y Zhang, Y Sun, JW Chen, S Subudhi, W Ho, GY Lee, ... bioRxiv, 2023.02. 06.527377, 2023 | 2 | 2023 |
1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer R Jain, N Talele, H Kumra, IG Dos Santos, S Roberge, W Ho, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts H Liu, WW Ho, K Naxerova, J Grahovac, H Nia, I Chen, JM Posada, ... Cancer Research 79 (24_Supplement), A18-A18, 2019 | 1 | 2019 |
Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma J Ren, Z Amoozgar, TP Uccello, PJ Lei, Y Zhao, WW Ho, P Huang, ... Proceedings of the National Academy of Sciences 122 (4), e2319474122, 2025 | | 2025 |
A Novel Polymersome Nanocarrier Promotes Anti‐Tumour Immunity by Improved Priming of CD8+ T Cells RJ Dress, WW Ho, V Ho, JH Lam, FM Décaillot, G Sinsinbar, J Soo, ... Immunology, 2025 | | 2025 |
1517 Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer DB Mahat, H Kumra, E Metcalf, S Castro, K Nguyen, WW Ho, I Chen, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |