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William W Ho
William W Ho
Research Scientist, Singapore Immunology Network
Verifisert e-postadresse på immunol.a-star.edu.sg
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Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases
NN Rahbari, D Kedrin, J Incio, H Liu, WW Ho, HT Nia, CM Edrich, K Jung, ...
Science translational medicine 8 (360), 360ra135-360ra135, 2016
2412016
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium
G Seano, HT Nia, KE Emblem, M Datta, J Ren, S Krishnan, J Kloepper, ...
Nature biomedical engineering 3 (3), 230-245, 2019
1922019
Roles of macrophages in tumor development: a spatiotemporal perspective
M Bied, WW Ho, F Ginhoux, C Blériot
Cellular & molecular immunology 20 (9), 983-992, 2023
1292023
Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer
K Jung, T Heishi, J Incio, Y Huang, EY Beech, M Pinter, WW Ho, ...
Proceedings of the National Academy of Sciences 114 (39), 10455-10460, 2017
1242017
Exercise Training Improves Tumor Control by Increasing CD8+ T-cell Infiltration via CXCR3 Signaling and Sensitizes Breast Cancer to Immune Checkpoint Blockade
IL Gomes-Santos, Z Amoozgar, AS Kumar, WW Ho, K Roh, NP Talele, ...
Cancer immunology research 9 (7), 765-778, 2021
1022021
Use of angiotensin system inhibitors is associated with immune activation and longer survival in nonmetastatic pancreatic ductal adenocarcinoma
H Liu, K Naxerova, M Pinter, J Incio, H Lee, K Shigeta, WW Ho, JA Crain, ...
Clinical Cancer Research 23 (19), 5959-5969, 2017
952017
Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy
DG Millar, RR Ramjiawan, K Kawaguchi, N Gupta, J Chen, S Zhang, ...
Nature biotechnology 38 (4), 420-425, 2020
712020
Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy
WW Ho, IL Gomes-Santos, S Aoki, M Datta, K Kawaguchi, NP Talele, ...
Proceedings of the National Academy of Sciences 118 (45), e2105323118, 2021
662021
In vivo compression and imaging in mouse brain to measure the effects of solid stress
HT Nia, M Datta, G Seano, S Zhang, WW Ho, S Roberge, P Huang, ...
Nature protocols, 1-20, 2020
472020
Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models
L Wu, S Vasilijic, Y Sun, J Chen, LD Landegger, Y Zhang, W Zhou, J Ren, ...
Science translational medicine 13 (602), eabd4816, 2021
342021
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models
M Datta, S Chatterjee, EM Perez, S Gritsch, S Roberge, M Duquette, ...
Proceedings of the National Academy of Sciences 120 (6), e2219199120, 2023
302023
The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy
WW Ho, MJ Pittet, D Fukumura, RK Jain
Cancer Cell 40 (7), 701-702, 2022
282022
Cancer cell plasticity and MHC-II–mediated immune tolerance promote breast cancer metastasis to lymph nodes
PJ Lei, ER Pereira, P Andersson, Z Amoozgar, JW Van Wijnbergen, ...
Journal of Experimental Medicine 220 (9), e20221847, 2023
272023
Exercise training improves tumor control by increasing CD8 (+) t-cell infiltration via CXCR3 signaling and sensitizes breast cancer to immune checkpoint blockade. Cancer …
IL Gomes-Santos, Z Amoozgar, AS Kumar, WW Ho, K Roh, NP Talele, ...
CIR-20-0499.[DOI][PMC free article][PubMed][Academic Search], 0
10
Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain
Z Yin, L Wu, Y Zhang, Y Sun, JW Chen, S Subudhi, W Ho, GY Lee, ...
bioRxiv, 2023.02. 06.527377, 2023
22023
1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer
R Jain, N Talele, H Kumra, IG Dos Santos, S Roberge, W Ho, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
12022
Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts
H Liu, WW Ho, K Naxerova, J Grahovac, H Nia, I Chen, JM Posada, ...
Cancer Research 79 (24_Supplement), A18-A18, 2019
12019
Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma
J Ren, Z Amoozgar, TP Uccello, PJ Lei, Y Zhao, WW Ho, P Huang, ...
Proceedings of the National Academy of Sciences 122 (4), e2319474122, 2025
2025
A Novel Polymersome Nanocarrier Promotes Anti‐Tumour Immunity by Improved Priming of CD8+ T Cells
RJ Dress, WW Ho, V Ho, JH Lam, FM Décaillot, G Sinsinbar, J Soo, ...
Immunology, 2025
2025
1517 Mutant-p53 amplifies Cxcl1 expression from distal enhancers blunting immune checkpoint inhibition efficacy in pancreatic cancer
DB Mahat, H Kumra, E Metcalf, S Castro, K Nguyen, WW Ho, I Chen, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023
2023
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Artikler 1–20