New insights into TCR β-selection A Dutta, BinZhao, PE Love Trends in Immunology 42 (8), 735-750, 2021 | 78 | 2021 |
Genetic ablation of Pim1 or pharmacologic inhibition with TP-3654 ameliorates myelofibrosis in murine models A Dutta, D Nath, Y Yang, BT Le, MFU Rahman, P Faughnan, Z Wang, ... Leukemia 36 (3), 746-759, 2022 | 40 | 2022 |
Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm MFU Rahman, Y Yang, BT Le, A Dutta, J Posyniak, P Faughnan, ... Nature Communications 13 (1), 5347, 2022 | 38 | 2022 |
New Insights into Epigenetic Regulation of T Cell Differentiation A Dutta, H Venkataganesh, PE Love Cells 10 (12), 3459, 2021 | 35 | 2021 |
U2af1 is required for survival and function of hematopoietic stem/progenitor cells A Dutta, Y Yang, BT Le, Y Zhang, O Abdel-Wahab, C Zang, G Mohi Leukemia 35 (8), 2382-2398, 2021 | 31 | 2021 |
Hmga2 promotes the development of myelofibrosis in Jak2V617F knockin mice by enhancing TGF-β1 and Cxcl12 pathways A Dutta, RE Hutchison, G Mohi Blood, The Journal of the American Society of Hematology 130 (7), 920-932, 2017 | 26 | 2017 |
STAT3 mutations are not sufficient to induce large granular lymphocytic leukaemia in mice A Dutta, D Yan, RE Hutchison, G Mohi British journal of haematology 180 (6), 911, 2016 | 23 | 2016 |
The PIM kinase inhibitor TP-3654 in combination with ruxolitinib exhibits marked improvement of myelofibrosis in murine models D Nath, A Dutta, Y Yang, C Whatcott, SL Warner, G Mohi Blood 132, 54, 2018 | 16 | 2018 |
CDK6 is a therapeutic target in myelofibrosis A Dutta, D Nath, Y Yang, BT Le, G Mohi Cancer Research 81 (16), 4332-4345, 2021 | 12 | 2021 |
THEMIS increases TCR signaling in CD4+CD8+ thymocytes by inhibiting the activity of the tyrosine phosphatase SHP1 S Choi, J Lee, T Hatzihristidis, G Gaud, A Dutta, A Arya, LM Clubb, ... Science Signaling 16 (784), eade1274, 2023 | 8 | 2023 |
Epigenetic regulation of T cell development A Dutta, H Venkataganesh, PE Love International Reviews of Immunology 42 (1), 82-90, 2023 | 8 | 2023 |
GRB2 promotes thymocyte positive selection by facilitating THEMIS-mediated inactivation of SHP1 S Choi, T Hatzihristidis, G Gaud, A Dutta, J Lee, A Arya, LM Clubb, ... Journal of Experimental Medicine 220 (7), e20221649, 2023 | 5 | 2023 |
The NF-KB inhibitor DMAPT in combination with ruxolitinib displays efficacy in Jak2V617F knock-in mouse model of myeloproliferative neoplasms Y Yang, D Nath, A Dutta, PA Crooks, G Mohi Blood 132, 1783, 2018 | 3 | 2018 |
The PIM kinase inhibitor TP-3654 demonstrates efficacy in a murine model of myelofibrosis A Dutta, D Nath, Y Yang, G Mohi Cancer Research 78 (13_Supplement), 1874-1874, 2018 | 3 | 2018 |
The CDK6 Inhibitor Palbociclib in Combination with Ruxolitinib Remarkably Improves Myelofibrosis in Murine Models G Mohi, A Dutta, D Nath, Y Yang Blood 134, 4200, 2019 | 2 | 2019 |
Genetic Deletion or Pharmacologic Inhibition of PTPN11 Impedes the Development and Progression of Myeloproliferative Neoplasms Induced By JAK2V617F and MPLW515L Mutants G Mohi, Y Yang, MA Sayem, BT Le, F Ather, A Dutta, S Abbas Blood 142, 739, 2023 | 1 | 2023 |
SRSF2 mutation reduces polycythemia and impairs hematopoietic progenitor functions in JAK2V617F-driven myeloproliferative neoplasm Y Yang, S Abbas, MA Sayem, A Dutta, G Mohi Blood Cancer Journal 13 (1), 171, 2023 | 1 | 2023 |
IL-1 Signaling Promotes Clonal Expansion and Progression of Bone Marrow Fibrosis in JAK2V617F-Induced Myeloproliferative Neoplasm MFU Rahman, Y Yang, BT Le, A Dutta, P Faughnan, G Mohi Blood 138 (Supplement 1), 2540-2540, 2021 | 1 | 2021 |
The RNA Splicing Factor U2AF1 Controls Hematopoietic Stem Cell Survival and Function A Dutta, Y Yang, B Le, G Mohi Blood, 2020 | 1 | 2020 |
Inhibition of SHP2 Ameliorates JAK2V617F-Induced Myeloproliferative Neoplasms Y Yang, BT Le, A Dutta, G Mohi Blood 138 (Supplement 1), 1465-1465, 2021 | | 2021 |