Shih-Chin James Cheng

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Mihai NeteaVerifisert e-postadresse på lembatherapeutics.com
Leo JoostenRadboud UMC Nijmegen, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-NapocaVerifisert e-postadresse på radboudumc.nl
Sanne SmeekensClinical Laboratory GeneticistVerifisert e-postadresse på radboudumc.nl
Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theVerifisert e-postadresse på umcg.nl
Vinod Kumar Magadi GopalaiahAssociate Professor/Research Group Leader at RadboudUMC, department of Internal MedicineVerifisert e-postadresse på radboudumc.nl
Mark GresnigtJunior Research Group Adaptive Pathogenicity Strategies, Hans Knöll Institut, Leibniz Institute forVerifisert e-postadresse på leibniz-hki.de
Hsieh SLGenomics Research Center, Academia SinicaVerifisert e-postadresse på gate.sinica.edu.tw
Evangelos Giamarellos-BourboulisNational and Kapodistrian University of Athens, Medical SchoolVerifisert e-postadresse på med.uoa.gr
David L. WilliamsEast Tennessee State UniversityVerifisert e-postadresse på etsu.edu
Chi-Huey WongThe Scripps Research Institute; Academia SinicaVerifisert e-postadresse på gate.sinica.edu.tw
Duccio CavalieriProfessor of Microbiology University of FlorenceVerifisert e-postadresse på unifi.it
Thirumala-Devi KannegantiSt. Jude Children's Research HospitalVerifisert e-postadresse på stjude.org
Matthijs KoxAssistant Professor, department of Intensive Care Medicine, Radboud University Medical CentreVerifisert e-postadresse på radboudumc.nl
Ganesh R. ManjeriGlaxoSmithKline Asia Private LimitedVerifisert e-postadresse på gsk.com
Suzanne van SommerenPhD studentVerifisert e-postadresse på umcg.nl
Cleo van DiemenDept of Genetics, University Medical Center GroningenVerifisert e-postadresse på umcg.nl
I. JoostenRadboud University Medical Centre, Nijmegen, The NetherlandsVerifisert e-postadresse på radboudumc.nl
Hans JPM KoenenRadboud University Medical Center, Nijmegen, The NetherlandsVerifisert e-postadresse på radboudumc.nl
Bernhard HubeDepartment of Microbial Pathogenicity mechanisms - Hans Knöll InstituteVerifisert e-postadresse på hki-jena.de

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Shih-Chin James Cheng

Xiamen University, School of Life Science

Verifisert e-postadresse på xmu.edu.cn - Startside

Trained immunity Immunometabolism innate immune memory inflammation mediated diseases immunology


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mTOR-and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity SC Cheng, J Quintin, RA Cramer, KM Shepardson, S Saeed, V Kumar, ... science 345 (6204), 1250684, 2014	2038	2014
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity S Saeed, J Quintin, HHD Kerstens, NA Rao, A Aghajanirefah, F Matarese, ... science 345 (6204), 1251086, 2014	1654	2014
Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ... Cell metabolism 24 (6), 807-819, 2016	783	2016
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ... Nature immunology 17 (4), 406-413, 2016	569	2016
CLEC5A is critical for dengue-virus-induced lethal disease ST Chen, YL Lin, MT Huang, MF Wu, SC Cheng, HY Lei, CK Lee, ... Nature 453 (7195), 672-676, 2008	476	2008
The macrophage mannose receptor induces IL-17 in response to Candida albicans FL van de Veerdonk, RJ Marijnissen, BJ Kullberg, HJPM Koenen, ... Cell host & microbe 5 (4), 329-340, 2009	428	2009
Human TLR10 is an anti-inflammatory pattern-recognition receptor M Oosting, SC Cheng, JM Bolscher, R Vestering-Stenger, TS Plantinga, ... Proceedings of the National Academy of Sciences 111 (42), E4478-E4484, 2014	349	2014
Interplay between Candida albicans and the mammalian innate host defense SC Cheng, LAB Joosten, BJ Kullberg, MG Netea Infection and immunity 80 (4), 1304-1313, 2012	346	2012
Innate immune memory: towards a better understanding of host defense mechanisms J Quintin, SC Cheng, JWM van Der Meer, MG Netea Current opinion in immunology 29, 1-7, 2014	307	2014
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans SC Cheng, FL van de Veerdonk, M Lenardon, M Stoffels, T Plantinga, ... Journal of leukocyte biology 90 (2), 357-366, 2011	226	2011
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C Van Diemen, ... Nature communications 4 (1), 1342, 2013	209	2013
Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells IV Ene, SC Cheng, MG Netea, AJP Brown Infection and immunity 81 (1), 238-248, 2013	160	2013
Anti‐Aspergillus human host defence relies on type 1 T helper (Th1), rather than type 17 T helper (Th17), cellular immunity LYA Chai, F Van De Veerdonk, RJ Marijnissen, SC Cheng, AL Khoo, ... Immunology 130 (1), 46-54, 2010	156	2010
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells E Lachmandas, M Beigier‐Bompadre, SC Cheng, V Kumar, ... European journal of immunology 46 (11), 2574-2586, 2016	154	2016
Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast DW Lowman, RR Greene, DW Bearden, MD Kruppa, M Pottier, ... Journal of Biological Chemistry 289 (6), 3432-3443, 2014	154	2014
Ubiquitin ligase TRIM62 regulates CARD9-mediated anti-fungal immunity and intestinal inflammation Z Cao, KL Conway, RJ Heath, JS Rush, ES Leshchiner, ZG Ramirez-Ortiz, ... Immunity 43 (4), 715-726, 2015	133	2015
Fungal chitin induces trained immunity in human monocytes during cross-talk of the host with Saccharomyces cerevisiae L Rizzetto, DC Ifrim, S Moretti, N Tocci, SC Cheng, J Quintin, G Renga, ... Journal of Biological Chemistry 291 (15), 7961-7972, 2016	132	2016
The interplay between central metabolism and innate immune responses SC Cheng, LAB Joosten, MG Netea Cytokine & growth factor reviews 25 (6), 707-713, 2014	112	2014
Candida albicans dampens host defense by downregulating IL-17 production SC Cheng, F van de Veerdonk, S Smeekens, LAB Joosten, ... The Journal of Immunology 185 (4), 2450-2457, 2010	112	2010
Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors H Laayouni, M Oosting, P Luisi, M Ioana, S Alonso, I Ricaño-Ponce, ... Proceedings of the National Academy of Sciences 111 (7), 2668-2673, 2014	107	2014

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