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Marc Dämgen
Marc Dämgen
Stanford University
Verifisert e-postadresse på stanford.edu
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Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity
DJ Huggins, PC Biggin, MA Dämgen, JW Essex, SA Harris, ...
Wiley Interdisciplinary Reviews: Computational Molecular Science 9 (3), e1393, 2019
1712019
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD
C Cao, X Barros-Álvarez, S Zhang, K Kim, MA Dämgen, O Panova, ...
Neuron 110 (19), 3154-3167. e7, 2022
972022
Selective G protein signaling driven by substance P–neurokinin receptor dynamics
JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ...
Nature chemical biology 18 (1), 109-115, 2022
752022
A refined open state of the glycine receptor obtained via molecular dynamics simulations
MA Dämgen, PC Biggin
Structure 28 (1), 130-139. e2, 2020
452020
State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane
MA Dämgen, PC Biggin
PLoS computational biology 17 (2), e1007856, 2021
222021
Computational methods to examine conformational changes and ligand-binding properties: Examples in neurobiology
MA Dämgen, PC Biggin
Neuroscience Letters 700, 9-16, 2019
132019
The startle disease mutation E103K impairs activation of human homomeric α1 glycine receptors by disrupting an intersubunit salt bridge across the agonist binding site
F Safar, E Hurdiss, M Erotocritou, T Greiner, R Lape, MW Irvine, G Fang, ...
Journal of Biological Chemistry 292 (12), 5031-5042, 2017
102017
Comment on “On the Functional Annotation of open-channel structures in the glycine receptor”
MA Dämgen, AM Zaki, PC Biggin
Structure 28 (6), 601-603, 2020
22020
Selective G protein signaling driven by substance P-neurokinin receptor structural dynamics
JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ...
bioRxiv, 2021.05. 16.444192, 2021
12021
Signaling Snapshots of 5-HT 2BR Activated by the Prototypical Psychedelic LSD
C Cao, X Barros-Álvarez, S Zhang, K Kim, MA Dämgen, O Panova, ...
1
Heterocyclic compounds as 5ht2a biased agonists
J Manish, S SLOCUM, G SKINIOTIS, X BARROS, J Jin, HU KANISKAN, ...
2023
Investigating the function of a pentameric ligand-gated ion channel with molecular simulation
MA Daemgen
University of Oxford, 2019
2019
Alternative Binding Mode of Full and Partial Agonists in a Pentameric Ligand-Gated Ion Channel Stabilises Loop C in an Open Conformation
MA Dämgen, T Greiner, R Lape, LG Sivilotti, PC Biggin
Biophysical Journal 114 (3), 297a, 2018
2018
Binding Modes of Full and Partial Agonists in the Orthosteric Binding Site of the Glycine Receptor
MA Dämgen, T Greiner, R Lape, LG Sivilotti, PC Biggin
Biophysical Journal 112 (3), 556a, 2017
2017
Henchman, RH,... van der Kamp, MW (2018). Biomolecular simulations: from dynamics and mechanisms to computational assays of biological activity. Wiley Interdisciplinary Reviews …
DJ Huggins, PC Biggin, MA Dämgen, JW Essex, SA Harris
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Artikler 1–15