| High-precision isothermal titration calorimetry with automated peak-shape analysis S Keller, C Vargas, H Zhao, G Piszczek, CA Brautigam, P Schuck Analytical chemistry 84 (11), 5066-5073, 2012 | 591 | 2012 |
| Calculations and publication-quality illustrations for analytical ultracentrifugation data CA Brautigam Methods in enzymology 562, 109-133, 2015 | 561 | 2015 |
| Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes CA Brautigam, TA Steitz Current opinion in structural biology 8 (1), 54-63, 1998 | 512 | 1998 |
| The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop X Zhang, J Wu, F Du, H Xu, L Sun, Z Chen, CA Brautigam, X Zhang, ... Cell reports 6 (3), 421-430, 2014 | 493 | 2014 |
| Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response X Jiang, LN Kinch, CA Brautigam, X Chen, F Du, NV Grishin, ZJ Chen Immunity 36 (6), 959-973, 2012 | 448 | 2012 |
| Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana CA Brautigam, BS Smith, Z Ma, M Palnitkar, DR Tomchick, M Machius, ... Proceedings of the National Academy of Sciences 101 (33), 12142-12147, 2004 | 369 | 2004 |
| Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions CA Brautigam, H Zhao, C Vargas, S Keller, P Schuck Nature protocols 11 (5), 882, 2016 | 304 | 2016 |
| Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences JL Mendoza, A Schmidt, Q Li, E Nuvaga, T Barrett, RJ Bridges, ... Cell 148 (1-2), 164-174, 2012 | 296 | 2012 |
| A TOG: αβ-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase P Ayaz, X Ye, P Huddleston, CA Brautigam, LM Rice Science 337 (6096), 857-860, 2012 | 274 | 2012 |
| Arp2/3 complex is bound and activated by two WASP proteins SB Padrick, LK Doolittle, CA Brautigam, DS King, MK Rosen Proceedings of the National Academy of Sciences 108 (33), E472-E479, 2011 | 268 | 2011 |
| Hierarchical regulation of WASP/WAVE proteins SB Padrick, HC Cheng, AM Ismail, SC Panchal, LK Doolittle, S Kim, ... Molecular cell 32 (3), 426-438, 2008 | 255 | 2008 |
| Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates CA Brautigam, TA Steitz Journal of molecular biology 277 (2), 363-377, 1998 | 254 | 1998 |
| Overview of current methods in sedimentation velocity and sedimentation equilibrium analytical ultracentrifugation H Zhao, CA Brautigam, R Ghirlando, P Schuck Current protocols in protein science 71 (1), 20.12. 1-20.12. 49, 2013 | 239 | 2013 |
| Side chain and backbone contributions of Phe508 to CFTR folding PH Thibodeau, CA Brautigam, M Machius, PJ Thomas Nature structural & molecular biology 12 (1), 10, 2005 | 225 | 2005 |
| Structural basis of histone demethylation by LSD1 revealed by suicide inactivation M Yang, JC Culhane, LM Szewczuk, CB Gocke, CA Brautigam, ... Nature structural & molecular biology 14 (6), 535, 2007 | 222 | 2007 |
| High-precision, automated integration of multiple isothermal titration calorimetric thermograms: new features of NITPIC TH Scheuermann, CA Brautigam Methods 76, 87-98, 2015 | 218 | 2015 |
| Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites B Chen, HT Chou, CA Brautigam, W Xing, S Yang, L Henry, LK Doolittle, ... Elife 6, e29795, 2017 | 189 | 2017 |
| On the acquisition and analysis of microscale thermophoresis data TH Scheuermann, SB Padrick, KH Gardner, CA Brautigam Analytical biochemistry 496, 79-93, 2016 | 179 | 2016 |
| Crystal structure of human dihydrolipoamide dehydrogenase: NAD+/NADH binding and the structural basis of disease-causing mutations CA Brautigam, JL Chuang, DR Tomchick, M Machius, DT Chuang Journal of molecular biology 350 (3), 543-552, 2005 | 160 | 2005 |
| Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature structural & molecular biology 23 (4), 293, 2016 | 155 | 2016 |