| Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease SP Yun, TI Kam, N Panicker, SM Kim, Y Oh, JS Park, SH Kwon, YJ Park, ... Nature medicine 24 (7), 931-938, 2018 | 1005 | 2018 |
| T cells from patients with Parkinson’s disease recognize α-synuclein peptides D Sulzer, RN Alcalay, F Garretti, L Cote, E Kanter, J Agin-Liebes, C Liong, ... Nature 546 (7660), 656-661, 2017 | 835 | 2017 |
| Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3 X Mao, MT Ou, SS Karuppagounder, TI Kam, X Yin, Y Xiong, P Ge, ... Science 353 (6307), aah3374, 2016 | 748 | 2016 |
| Poly (ADP-ribose) drives pathologic a-synuclein neurodegeneration in Parkinson’s disease TI Kam, X Mao, H Park, SC Chou, SS Karuppagounder, GE Umanah, ... Science 362, 2018 | 461 | 2018 |
| Visible light induced photocatalytic degradation of rhodamine B on one-dimensional iron oxide particles X Zhou, H Yang, C Wang, X Mao, Y Wang, Y Yang, G Liu The Journal of Physical Chemistry C 114 (40), 17051-17061, 2010 | 276 | 2010 |
| GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers S Kim, SP Yun, S Lee, GE Umanah, VVR Bandaru, X Yin, P Rhee, ... Proceedings of the National Academy of Sciences 115 (4), 798-803, 2018 | 199 | 2018 |
| Nanomaterials for reducing amyloid cytotoxicity M Zhang, X Mao, Y Yu, CX Wang, YL Yang, C Wang Advanced materials 25 (28), 3780-3801, 2013 | 194 | 2013 |
| Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration S Brahmachari, P Ge, SH Lee, D Kim, SS Karuppagounder, M Kumar, ... The Journal of clinical investigation 126 (8), 2970-2988, 2016 | 177 | 2016 |
| Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease N Panicker, TI Kam, H Wang, S Neifert, SC Chou, M Kumar, ... Neuron 110 (15), 2422-2437. e9, 2022 | 129 | 2022 |
| Nanozyme scavenging ROS for prevention of pathologic α-synuclein transmission in Parkinson’s disease YQ Liu, Y Mao, E Xu, H Jia, S Zhang, VL Dawson, TM Dawson, YM Li, ... Nano Today 36, 101027, 2021 | 116 | 2021 |
| Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease S Zhang, YQ Liu, C Jia, YJ Lim, G Feng, E Xu, H Long, Y Kimura, Y Tao, ... Proceedings of the National Academy of Sciences 118 (26), e2011196118, 2021 | 93 | 2021 |
| Chaperon-mediated single molecular approach toward modulating Aβ peptide aggregation L Liu, L Zhang, X Mao, L Niu, Y Yang, C Wang Nano letters 9 (12), 4066-4072, 2009 | 93 | 2009 |
| Robust kinase-and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice Y Xiong, S Neifert, SS Karuppagounder, Q Liu, JN Stankowski, BD Lee, ... Proceedings of the National Academy of Sciences 115 (7), 1635-1640, 2018 | 91 | 2018 |
| Pathological endogenous α-synuclein accumulation in oligodendrocyte precursor cells potentially induces inclusions in multiple system atrophy S Kaji, T Maki, H Kinoshita, N Uemura, T Ayaki, Y Kawamoto, T Furuta, ... Stem cell reports 10 (2), 356-365, 2018 | 85 | 2018 |
| Determinants of seeding and spreading of α-synuclein pathology in the brain MT Henrich, FF Geibl, H Lakshminarasimhan, A Stegmann, BI Giasson, ... Science Advances 6 (46), eabc2487, 2020 | 84 | 2020 |
| Incident dementia and long-term exposure to constituents of fine particle air pollution: A national cohort study in the United States L Shi, Q Zhu, Y Wang, H Hao, H Zhang, J Schwartz, H Amini, ... Proceedings of the National Academy of Sciences 120 (1), e2211282119, 2023 | 80 | 2023 |
| Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies XB Mao, CX Wang, XK Wu, XJ Ma, L Liu, L Zhang, L Niu, YY Guo, DH Li, ... Proceedings of the National Academy of Sciences 108 (49), 19605-19610, 2011 | 75 | 2011 |
| Amyloid β (1–42) folding multiplicity and single-molecule binding behavior studied with STM X Ma, L Liu, X Mao, L Niu, K Deng, W Wu, Y Li, Y Yang, C Wang Journal of molecular biology 388 (4), 894-901, 2009 | 70 | 2009 |
| Molecular-level evidence of the surface-induced transformation of peptide structures revealed by scanning tunneling microscopy X Mao, Y Wang, L Liu, L Niu, Y Yang, C Wang Langmuir 25 (16), 8849-8853, 2009 | 62 | 2009 |
| Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease S Brahmachari, S Lee, S Kim, C Yuan, SS Karuppagounder, P Ge, R Shi, ... Brain 142 (8), 2380-2401, 2019 | 61 | 2019 |
Ted M. DawsonDirector, Institute for Cell Engineering, Professor of Neurology and Neuroscience, JHUSoMVerifisert e-postadresse på jhmi.edu