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Vivien Low
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Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes
R Di Micco, B Fontanals-Cirera, V Low, P Ntziachristos, SK Yuen, ...
Cell reports 9 (1), 234-247, 2014
2502014
Age-induced accumulation of methylmalonic acid promotes tumour progression
AP Gomes, D Ilter, V Low, JE Endress, J Fernández-García, ...
Nature 585 (7824), 283-287, 2020
1942020
Unique metabolic adaptations dictate distal organ-specific metastatic colonization
T Schild, V Low, J Blenis, AP Gomes
Cancer cell 33 (3), 347-354, 2018
1812018
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization
AP Gomes, D Ilter, V Low, A Rosenzweig, ZJ Shen, T Schild, MA Rivas, ...
Cancer Cell 36 (4), 402-417. e13, 2019
882019
Altered propionate metabolism contributes to tumour progression and aggressiveness
AP Gomes, D Ilter, V Low, S Drapela, T Schild, E Mullarky, J Han, I Elia, ...
Nature metabolism 4 (4), 435-443, 2022
642022
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression
Z Li, V Low, V Luga, J Sun, E Earlie, B Parang, K Shobana Ganesh, ...
Nature Communications 13 (1), 6239, 2022
332022
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma
T Schild, MR McReynolds, C Shea, V Low, BE Schaffer, JM Asara, ...
Cell Reports 35 (11), 2021
302021
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment
V Low, Z Li, J Blenis
Science signaling 15 (759), eabj4220, 2022
292022
The Tc1/mariner transposable element family shapes genetic variation and gene expression in the protist Trichomonas vaginalis
M Bradic, SD Warring, V Low, JM Carlton
Mobile DNA 5, 1-11, 2014
282014
NADK-mediated de novo NADP (H) synthesis is a metabolic adaptation essential for breast cancer metastasis
D Ilter, S Drapela, T Schild, NP Ward, E Adhikari, V Low, J Asara, ...
Redox Biology 61, 102627, 2023
192023
Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet
K Xu, Y Guo, Y Wang, Y Ren, V Low, S Cho, L Ping, K Peng, X Li, Y Qiu, ...
Aging Cell 22 (2), e13760, 2023
162023
Targeting the premetastatic niche: epigenetic therapies in the spotlight
V Low, J Blenis, AP Gomes
Signal Transduction and Targeted Therapy 5 (1), 68, 2020
102020
Age-induced methylmalonic acid accumulation promotes tumor progression
AP Gomes, D Ilter, V Low, JE Endress, J Fernández-García, ...
Nature 585 (7824), 283, 2020
32020
NADK upregulation is an essential metabolic adaptation that enables breast cancer metastatic colonization
D Ilter, T Schild, NP Ward, S Drapela, E Adhikari, V Low, E Le-Lau, ...
bioRxiv, 2022.03. 25.485887, 2022
22022
Stromal KITL/SCF promotes pancreas tissue homeostasis and restrains tumor progression
MK Oñate, C Oon, S Bhattacharyya, V Low, C Chen, X Zhao, Z Yan, ...
bioRxiv, 2024
12024
Methylmalonic acid is elevated in non-small cell lung cancer and promotes drug resistance
B Parang, Z Li, V Low, J Endress, M Malbari, A Saxena, N Altorki, J Blenis
Cancer Research 82 (12_Supplement), 2378-2378, 2022
12022
Stromal KITL/SCF maintains pancreas tissue homeostasis and restrains tumor progression
MK Oñate, C Oon, S Bhattacharyya, V Low, C Chen, X Zhao, F Arnold, ...
Cancer Discovery, 2025
2025
The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer
M Shafer, V Low, Z Li, J Blenis
Cell Metabolism 37 (2), 316-329, 2025
2025
SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice
K Xu, Y Wang, F Wang, Y Guo, Y Ren, V Low, S Cho, Q Liu, Y Qiu, X Li, ...
Journal of Cachexia, Sarcopenia and Muscle 16 (1), e13734, 2025
2025
Methylmalonic acid in TME signaling
V Low, Z Li, A Laughney, W Jin, N Dephoure, V Luga, E Earlie, B Parang, ...
Cancer Research 82 (12_Supplement), 3175-3175, 2022
2022
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Artikler 1–20