Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes R Di Micco, B Fontanals-Cirera, V Low, P Ntziachristos, SK Yuen, ... Cell reports 9 (1), 234-247, 2014 | 250 | 2014 |
Age-induced accumulation of methylmalonic acid promotes tumour progression AP Gomes, D Ilter, V Low, JE Endress, J Fernández-García, ... Nature 585 (7824), 283-287, 2020 | 194 | 2020 |
Unique metabolic adaptations dictate distal organ-specific metastatic colonization T Schild, V Low, J Blenis, AP Gomes Cancer cell 33 (3), 347-354, 2018 | 181 | 2018 |
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization AP Gomes, D Ilter, V Low, A Rosenzweig, ZJ Shen, T Schild, MA Rivas, ... Cancer Cell 36 (4), 402-417. e13, 2019 | 88 | 2019 |
Altered propionate metabolism contributes to tumour progression and aggressiveness AP Gomes, D Ilter, V Low, S Drapela, T Schild, E Mullarky, J Han, I Elia, ... Nature metabolism 4 (4), 435-443, 2022 | 64 | 2022 |
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Z Li, V Low, V Luga, J Sun, E Earlie, B Parang, K Shobana Ganesh, ... Nature Communications 13 (1), 6239, 2022 | 33 | 2022 |
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma T Schild, MR McReynolds, C Shea, V Low, BE Schaffer, JM Asara, ... Cell Reports 35 (11), 2021 | 30 | 2021 |
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment V Low, Z Li, J Blenis Science signaling 15 (759), eabj4220, 2022 | 29 | 2022 |
The Tc1/mariner transposable element family shapes genetic variation and gene expression in the protist Trichomonas vaginalis M Bradic, SD Warring, V Low, JM Carlton Mobile DNA 5, 1-11, 2014 | 28 | 2014 |
NADK-mediated de novo NADP (H) synthesis is a metabolic adaptation essential for breast cancer metastasis D Ilter, S Drapela, T Schild, NP Ward, E Adhikari, V Low, J Asara, ... Redox Biology 61, 102627, 2023 | 19 | 2023 |
Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat diet K Xu, Y Guo, Y Wang, Y Ren, V Low, S Cho, L Ping, K Peng, X Li, Y Qiu, ... Aging Cell 22 (2), e13760, 2023 | 16 | 2023 |
Targeting the premetastatic niche: epigenetic therapies in the spotlight V Low, J Blenis, AP Gomes Signal Transduction and Targeted Therapy 5 (1), 68, 2020 | 10 | 2020 |
Age-induced methylmalonic acid accumulation promotes tumor progression AP Gomes, D Ilter, V Low, JE Endress, J Fernández-García, ... Nature 585 (7824), 283, 2020 | 3 | 2020 |
NADK upregulation is an essential metabolic adaptation that enables breast cancer metastatic colonization D Ilter, T Schild, NP Ward, S Drapela, E Adhikari, V Low, E Le-Lau, ... bioRxiv, 2022.03. 25.485887, 2022 | 2 | 2022 |
Stromal KITL/SCF promotes pancreas tissue homeostasis and restrains tumor progression MK Oñate, C Oon, S Bhattacharyya, V Low, C Chen, X Zhao, Z Yan, ... bioRxiv, 2024 | 1 | 2024 |
Methylmalonic acid is elevated in non-small cell lung cancer and promotes drug resistance B Parang, Z Li, V Low, J Endress, M Malbari, A Saxena, N Altorki, J Blenis Cancer Research 82 (12_Supplement), 2378-2378, 2022 | 1 | 2022 |
Stromal KITL/SCF maintains pancreas tissue homeostasis and restrains tumor progression MK Oñate, C Oon, S Bhattacharyya, V Low, C Chen, X Zhao, F Arnold, ... Cancer Discovery, 2025 | | 2025 |
The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer M Shafer, V Low, Z Li, J Blenis Cell Metabolism 37 (2), 316-329, 2025 | | 2025 |
SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice K Xu, Y Wang, F Wang, Y Guo, Y Ren, V Low, S Cho, Q Liu, Y Qiu, X Li, ... Journal of Cachexia, Sarcopenia and Muscle 16 (1), e13734, 2025 | | 2025 |
Methylmalonic acid in TME signaling V Low, Z Li, A Laughney, W Jin, N Dephoure, V Luga, E Earlie, B Parang, ... Cancer Research 82 (12_Supplement), 3175-3175, 2022 | | 2022 |